An observational study in Gastrointestinal Cancer, Colorectal Cancer and Gastric Cancer, sponsored by Paul G. Kemps, MD. Status unknown at 2 sites in Netherlands. Open to participants aged 0 Years to 24 Years. Per ClinicalTrials.gov, last updated 2023-01-23.
Sponsored by Paul G. Kemps, MD · Observational
The goal of this observational population-based cohort study is to investigate the clinical characteristics and outcomes of children and adolescents with primary gastrointestinal malignancies registered in the publicly available Surveillance, Epidemiology, and End Results (SEER) 17 database during 2000-2019.
The investigators aim to describe the patient and tumor characteristics, treatments, and outcomes of children and adolescents diagnosed with primary gastrointestinal malignancies, and to analyze these data for trends over time. In addition, the investigators want to explore independent prognostic factors for overall survival. Finally, the investigators want to describe subsequent primary malignancies diagnosed among patients from the study cohort, as well as to calculate their risk of developing a second primary cancer relative to the general population. Data on children (aged 0-17 years at diagnosis) and young people aged 18-24 years at diagnosis are analyzed separately. Special focus is laid on patients with primary carcinomas of the gastrointestinal tract; particularly colorectal carcinoma.
392 studies on the registry are indexed under Burkitt Lymphoma; 114 are open to participants now.
This study's planned enrollment of 2,500 is above the median of 300 across 25 observational studies indexed under Burkitt Lymphoma.
Browse Burkitt Lymphoma studies →This is the only study on the registry with Paul G. Kemps, MD as lead sponsor.
Counted across the registry records on this site, refreshed daily.
All patients aged 0-24 years with a diagnosis of a primary gastrointestinal malignancy as their first primary malignancy in the SEER 17 database from 2000 until (and including) 2019.
Exclusion Criteria:
Patients aged 0-17 years at primary gastrointestinal cancer diagnosis
Patients aged 18-24 years at primary gastrointestinal cancer diagnosis
Overall survival
Defined as the time between the date of diagnosis and the date of death from any cause (event) or date of last follow-up.
Time frame: 2000-2019
Standardized incidence of second primary malignancies
Standardized incidence of second primary malignancies in patients who survived (i) two or more months, or (ii) five or more years after initial gastrointestinal cancer diagnosis, relative to the general population.
Time frame: 2000-2019
Documents are hosted by the registry — open the source record to download them.
Plan to share: Yes — Data are publicly available through SEER under the SEER Research Data Use Agreement.
Supporting information: Study protocol, Sap, Analytic code
This study is status unknown, as verified in Jan 2023. You cannot join it, but the record below documents what was studied.
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