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Status unknownNCT05645848Updated Dec 12, 2022

The Rate and Predictors of Vaginal Bleeding Among Women With Placenta Previa

An observational study in Placenta Previa, Vaginal Bleeding and Antepartum Hemorrhage, sponsored by Assiut University. Status unknown. Open to female participants. Per ClinicalTrials.gov, last updated 2022-12-12.

Sponsored by Assiut University · Observational

The sponsor has not verified this record recently (last verified Dec 2022), so the status shown — last known as Not yet recruiting — may be out of date.
Study type
Observational
Model
Other
Time perspective
Cross-sectional
Enrollment
250
Sex
Female
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Study summary

Placenta previa is usually diagnosed when the placenta implanted in the lower uterine segment, thus partially or totally overlying the internal os . It occurs with an incidence of 0.3-0.5%. It is associated mainly with prior caesarean delivery . The condition is frequently complicated by invasion of placental villi beyond the decidua basalis causing placenta accreta . Placenta previa is a major cause of massive haemorrhage during pregnancy and after delivery . The antepartum bleeding from placenta previa- can be life-threatening, thus, the prediction of this bleeding is of great importance . It is important to distinguish between women at high and low risk for antepartum haemorrhage with placenta previa especially at late pregnancy . However, the potential risk factors for antepartum haemorrhage in women with placenta previa have not been thoroughly examined.

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Conditions studied

  • Placenta Previa
  • Vaginal Bleeding
  • Antepartum Hemorrhage
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In context

Placenta Previa

80 studies on the registry are indexed under Placenta Previa; 17 are open to participants now.

This study's planned enrollment of 250 is above the median of 100 across 32 observational studies indexed under Placenta Previa.

Browse Placenta Previa studies →

Lead sponsor

Assiut University is the lead sponsor of 5,078 studies on the registry; 2,178 are open to participants now.

Of its 14 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
Female
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

pregnant women with placenta previa

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Pregnant women ≥ 28 weeks.
  • Diagnosed to have placenta previa by ultrasound

Exclusion criteria

Exclusion Criteria:

  • Women with complicated pregnancies (e.g. preeclampsia, diabetes mellitus and cardiac, renal, antiphospholipid syndrome).
  • Women with premature rupture of membrane.
  • Women who will refuse to participate.
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Study design

Observational model
Other
Time perspective
Cross-sectional
Enrollment
250 participants (estimated)
Patient registry
No

Interventions

  • DeviceUltrasonography

    Abdominal ultrasound in pregnant women with placenta previa

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What researchers measure

Primary outcomes

  1. The rate of vaginal bleeding in women presented by placenta previa at third trimester of pregnancy.

    The rate of vaginal bleeding in women presented by placenta previa at third trimester of pregnancy.

    Time frame: Through study completion, an average of 1 and half year

Secondary outcomes

  1. Identification of the potential clinical and ultrasonographic predictors of antepartum hemorrhage in women with placenta previa at third trimester of pregnancy

    The result that the investigators will get from the study will help identify predictors of antepartum hemorrhage in pregnant women with placenta previa and hence preventing it, antepartum hemorrhage is a major life threatening complication of the disease wether to the baby or the mother

    Time frame: through study completion, an average of 1 and half year

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Study locations

No study locations are listed for this record.

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References and documents

Publications

  • Wu S, Kocherginsky M, Hibbard JU. Abnormal placentation: twenty-year analysis. Am J Obstet Gynecol. 2005 May;192(5):1458-61. doi: 10.1016/j.ajog.2004.12.074. PubMed 15902137 ↗
  • Shaamash AH, Ali MK, Attyia KM. Intramuscular 17alpha-hydroxyprogesterone caproate to decrease preterm delivery in women with placenta praevia: a randomised controlled trial. J Obstet Gynaecol. 2020 Jul;40(5):633-638. doi: 10.1080/01443615.2019.1645099. Epub 2019 Oct 31. PubMed 31670998 ↗
  • Shazly SA, Badee AY, Ali MK. The use of multiple 8 compression suturing as a novel procedure to preserve fertility in patients with placenta accreta: case series. Aust N Z J Obstet Gynaecol. 2012 Aug;52(4):395-9. doi: 10.1111/j.1479-828X.2012.01449.x. Epub 2012 Jun 9. PubMed 22681562 ↗
  • Nagase Y, Matsuzaki S, Endo M, Hara T, Okada A, Mimura K, Hiramatsu K, Kakigano A, Nakatsuka E, Miyake T, Takiuchi T, Ueda Y, Tomimatsu T, Kimura T. Placenta previa with posterior extrauterine adhesion: clinical features and management practice. BMC Surg. 2021 Jan 6;21(1):10. doi: 10.1186/s12893-020-01027-9. PubMed 33407322 ↗
  • Dashe JS. Toward consistent terminology of placental location. Semin Perinatol. 2013 Oct;37(5):375-9. doi: 10.1053/j.semperi.2013.06.017. PubMed 24176163 ↗
  • Love CD, Fernando KJ, Sargent L, Hughes RG. Major placenta praevia should not preclude out-patient management. Eur J Obstet Gynecol Reprod Biol. 2004 Nov 10;117(1):24-9. doi: 10.1016/j.ejogrb.2003.10.039. PubMed 15474239 ↗
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Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Start is estimated for Dec 2022; primary completion for Dec 2024, 24 months later.

How these figures are worked out, and which studies are left out of them.

Registered
Nov 4, 2022
First posted
Dec 12, 2022
StartEst.
Dec 2022
Primary completionEst.
Dec 2024
CompletionEst.
Jan 2025
Last update
Dec 12, 2022
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Dec 12, 2022, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT05645848
Lead sponsor
Assiut University
Responsible party
Ismail Omar Mohammed Ali (principal investigator, Assiut University) — Principal investigator
First posted
Dec 12, 2022
Start date
Dec 2022 (estimated)
Primary completion
Dec 2024 (estimated)
Completion
Jan 2025 (estimated)
Last update
Dec 12, 2022

Study contacts

Ismael O Ali, resident
Contact
Ismael_alyy@yahoo.com
+201033039300
Kamal M Zahran, professor
study chair · department of obstetrics and gynecology, faculty of medicine, Assuit University, Egypt
Mohamed K Ali, doctor
study director · department of obstetrics and gynecology, faculty of medicine, Assuit University, Egypt
Mohamed M Abd-allah, doctor
study director · department of obstetrics and gynecology, faculty of medicine, Assuit University, Egypt
Ismael O Ali, resident
principal investigator · department of obstetrics and gynecology, faculty of medicine, Assuit University, Egypt

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Dec 2022. You cannot join it, but the record below documents what was studied.

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