An interventional study of High Intensity Interval Gait training and Moderate Intensity Interval gait training in Multiple Sclerosis, sponsored by Hunter College of City University of New York. Status unknown at 1 site in United States. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2022-10-06.
Sponsored by Hunter College of City University of New York · Not applicable, Interventional, and Treatment
Over 90% of persons with MS (pwMS) complain of difficulty with walking. High intensity interval gait training (HIIGT), where persons alternate brief periods of walking at high speeds with periods of rest has been found to improve walking in other neurologic diagnoses. However its impact on pwMS is not known. Most gait training in MS is done continuously at a slower pace. The purpose of this study is to compare the effects of HIIGT to traditional Moderate Intensity Continuous Gait Training (MICGT) in pwMS.
Purpose: To determine whether pwMS will have greater improvements in gait with HIIGT as compared to MICGT.
Primary Question: Does HIIGT results in greater improvements in gait parameters in pwMS than MICGT? Secondary question: Will HIIGT result in greater improvements in balance, lower extremity strength, lower extremity range of motion and HR when compared to MICGT in pwMS?
Hypothesis: HIIGT will result in greater improvements in gait parameters in pwMS than MICGT.
Justification: Previous research has shown that MICGT, moderate intensity interval training and high intensity non-gait interval training is effective in pwMS. HIIGT has been shown to be effective in persons with stroke but the effects of HIIGT on pwMS are not known.
Outcomes and dissemination of information: We will present our findings at national conferences and submit manuscripts of our findings to the appropriate peer reviewed journal.
3,460 studies on the registry are indexed under Multiple Sclerosis; 661 are open to participants now.
This study's planned enrollment of 30 is below the median of 50 across 2,342 interventional studies indexed under Multiple Sclerosis.
Browse Multiple Sclerosis studies →Hunter College of City University of New York is the lead sponsor of 36 studies on the registry; 9 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
subjects will receive 3x/week high intensity interval training for 20 minutes over a 4 week period
Behavioral: High Intensity Interval Gait training
subjects will receive 3x/week moderate intensity continuous gait training for 20 minutes over a 4 week period
Behavioral: Moderate Intensity Interval gait training
Subjects will walk as fast as they can for 30 seconds, followed by a 60 second seated recovery. They will be guarded by a physical therapist at all times.
subjects will walk for 20 minutes at theri best comfortable pace
Change in Six minute walk test time from before to after the intervention
Subjects will walk for six minutes at their best comfortable pace. They will be guarded by physical therapist for the entire walk. Total distance, distance per minute, and heart rate will be measured.
Time frame: The test will be administered to all subjects one week before and one week after the intervention.The test will be administered to all subjects one week before and one week after the intervention.
Change in Functional gait assessment score from before to after the intervention
Used to assess balance during different walking conditions
Time frame: Will be done in the week before and the week after the intervention.Will be done in the week before and the week after the intervention.
Change in Hand held dynamometry values from before to after the intervention
Use of the strain gauge to determine lower extremity muscle strength
Time frame: Will be done the week before and the week after the intervention.
Change in Multiple sclerosis impact scale 29 from before to afterthe intervention
Quality of life measure where are the subject subjectively rates the impact of multiple sclerosis on their life
Time frame: Performed in the week before and the week after the intervention.
Plan to share: No
No publications or documents are linked to this record.
This study is status unknown, as verified in Sep 2022. You cannot join it, but the record below documents what was studied.
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Hunter College of City University of New York