An interventional study of Couples Health Project in Substance Use and HIV Infections, sponsored by Hunter College of City University of New York. Recruiting at 3 sites in United States. Open to male participants aged 18 Years to 55 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-09-17.
Sponsored by Hunter College of City University of New York · Not applicable, Interventional, and Health services research
This study utilizes a randomized controlled trial design to evaluate the efficacy of couples motivational interviewing (MI) to reduce the frequency and severity of illicit drug use and frequency of HIV transmission risk behavior (TRB). Participants are randomized to one of two conditions: couples MI or standard couples HIV testing and counseling (CHTC).
2,238 studies on the registry are indexed under Substance-Related Disorders; 409 are open to participants now.
This study's planned enrollment of 360 is above the median of 108 across 1,840 interventional studies indexed under Substance-Related Disorders.
Browse Substance-Related Disorders studies →Hunter College of City University of New York is the lead sponsor of 36 studies on the registry; 9 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The human immunodeficiency virus, which weakens the immune system.
Many studies now accept people whose HIV is controlled on treatment, judged by the viral load and the CD4 count. Check the limits this study sets.
HIV
The human immunodeficiency virus, which weakens the immune system.
Many studies now accept people whose HIV is controlled on treatment, judged by the viral load and the CD4 count. Check the limits this study sets.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Participants complete the standard Couples HIV Testing and Counseling session (CHTC).
A three-session intervention for couples addressing couples communication skills, substance use, sexual agreements. The intervention also includes couples HIV testing and counseling in the final session.
Behavioral: Couples Health Project
A 3-session, couples motivational Interviewing drug use and HIV risk reduction intervention
Also known as: CHP
Drug use Frequency
Number of reported days of illicit drug use (amphetamines, cocaine/crack, GHB, ketamine or ecstasy) reported on quarterly timeline follow-back assessments
Time frame: 9 Months
Urine assay for drug use
Positive urine screen for drug use assessed bi-annually
Time frame: 9 Months
CAS with casual partners
Number of total anal sex acts (insertive and receptive) with casual partners reported on quarterly timeline follow-back assessments in the absence of adequate PrEP coverage
Time frame: 9 Months
Bacterial sexually transmitted infections
Any chlamydia or gonorrhea diagnosis
Time frame: 9 Months
Binge Drinking
Number of days on which 5 or more drinks containing alcohol were reported on the quarterly timeline follow-back interview
Time frame: 9 Months
PrEP Uptake
self-reported receipt of a PrEP-prescription
Time frame: 9 months
Not enrolling at this site.
Not enrolling at this site.
Plan to share: No
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Hunter College of City University of New York