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CompletedNCT05146323OSPECTUpdated Dec 6, 2021

Optimization of 99mTc-Sestamibi Activities in SPECT/CT Myocardial Perfusion Imaging

An observational study in Coronary Heart Disease, sponsored by Centre Hospitalier Régional Metz-Thionville. Completed at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2021-12-06.

Sponsored by Centre Hospitalier Régional Metz-Thionville · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
294
Ages
18 Years and older
Sex
All
01

Study summary

This work suggests a methodology to adapt the injected radionuclide activity to the level of attenuation of each patient. The investigators propose a dose reduction adapted to the patient's weight, with no significant degradation of the image quality, in order to improve patients and staff radioprotection, standardize the image quality for easier clinical interpretation, and lead to radiopharmaceutical saving in the context of myocardial perfusion Imaging.

02

Conditions studied

  • Coronary Heart Disease

Keywords

  • Myocardial SPECT
  • Sestamibi
  • SmartZoom
  • Cardiofocal collimator
  • Dose optimization
03

In context

Heart Diseases

3,639 studies on the registry are indexed under Heart Diseases; 461 are open to participants now.

This study's enrollment of 294 is close to the median of 294 across 1,241 observational studies indexed under Heart Diseases.

Browse Heart Diseases studies →

Lead sponsor

Centre Hospitalier Régional Metz-Thionville is the lead sponsor of 118 studies on the registry; 20 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patient with myocardial perfusion Imaging in the context of coronary heart disease

Inclusion criteria

  • Patient underwent stress-test 99 mTc-Sestamibi SPECT/CT myocardial perfusion Imaging on a Siemens Intevo Bold Anger camera with the cardiofocal SmartZoom® collimator

Exclusion criteria

Exclusion Criteria:

  • None
05

Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
294 participants (actual)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Number of counts

    Number of counts in the myocardial region of interest

    Time frame: Day 1

Secondary outcomes

  1. Clinical evaluation

    Medical evaluation of image quality, in order to establish a correlation between the myocardial signal level and the clinical image quality

    Time frame: Day 1

07

Study locations

1 site
  • CHR Metz Thionville
    Metz, Moselle 57085, France
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 6, 2021, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT05146323
Lead sponsor
Centre Hospitalier Régional Metz-Thionville
Responsible party
Sponsor
First posted
Dec 6, 2021
Start date
Feb 11, 2021
Primary completion
Jun 30, 2021
Completion
Sep 24, 2021
Last update
Dec 6, 2021

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Nov 2021. You cannot join it, but the record below documents what was studied.

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