An observational study in Osteoarthritis of the Shoulder, Avascular Necrosis and Traumatic Arthritis, sponsored by Stryker Trauma and Extremities. Active, not recruiting at 8 sites in United States. Open to participants aged 22 Years and older. Per ClinicalTrials.gov, last updated 2026-09-01.
Sponsored by Stryker Trauma and Extremities (part of Stryker) · Observational
Among 105 studies in Osteonecrosis with a site in United States — 17 open to participants now, 33 under way, 1 of them phase 3. Osteonecrosis · United States.
Among the 105 studies in Osteonecrosis with a site in United States, this one is the 34th largest by enrollment of the 51 observational ones that give a count, is one of 3 that started in 2021, is one of 51 observational ones, reaches primary completion later than 9 of the 32 other live ones, and was the 84th registered.
286 studies on the registry are indexed under Osteonecrosis; 45 are open to participants now.
Browse Osteonecrosis studies →17 of the 105 studies in Osteonecrosis with a site in United States are open now. Recruiting first, the newest first:
University of California, Davis · Sites in United States
Ages 18–80
Johns Hopkins University · Sites in United States
Ages 18–90
Ohio State University · Sites in United States
Ages 18–50
Paragon 28 · Sites in United States
Ages 21+
Stryker Trauma and Extremities · Sites in United States, Canada, France and 2 more countries
Ages 18+
A study can be open while its sites in United States have not opened yet or have stopped. Only those recruiting at a site in United States →
Of the 23 Osteonecrosis studies recruiting now, 14 (61%) set no upper age limit and 4 (17%) stop at 75 or younger; 2 take children under 18; 2 take healthy volunteers.
This study: 22 Years and older · all sexes · no healthy volunteers.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
105 studies; the count open now beside each. This study's row is marked.
A study in two phases is counted once above. Listed by phase, each with its combined phases: Phase 1 5 · Phase 2 6 · Phase 3 3 · Phase 4 5
First in 1999; this study’s year is marked. 3 started in 2021.
By drug class, each counting the studies that test any of its medicines:
This study's enrollment of 76 is below the median of 121 across 127 observational studies indexed under Osteonecrosis.
Median enrollment 116 across the 54 interventional studies, 131 across the 51 observational. Of the 68 that completed or were terminated, 24 (35%) have results posted.
This tab as a report to print or save as PDF → With an account.
68 of 105 have an industry lead sponsor. The 10 most frequent:
This study is registered under Stryker Trauma and Extremities, one of the names counted as Stryker. Under that name alone:
Stryker Trauma and Extremities is the lead sponsor of 43 studies on the registry; 5 are open to participants now.
Stryker has 8 studies filed under Osteonecrosis — fewer than ten, so there is no comparison to draw.
6 of the studies in Osteonecrosis with a site in United States that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT03409718Zimmer BiometDatabase Retrieval for the Comprehensive Shoulder | 2026-12 |
| NCT01480440Zimmer BiometOutcomes Study of the Trabecular Metal (TM) Reverse Shoulder System | 2026-12 |
| NCT05706909The Cleveland ClinicThe Use of Genex in the Management of Early-Stage Osteonecrosis of the Femoral Head | 2026-12 |
| NCT03107520Children's Hospital of PhiladelphiaIntraoperative Contrast-Enhanced Ultrasound Evaluation of Blood Flow at the Time of Surgical Hip Reduction for DDH | 2027-04 |
| NCT05049993Stryker Trauma and ExtremitiesPyrocarbon Clinical Follow-up Study | 2027-05-31 |
Add all 6 to your calendar (.ics) → With an account.
Among the 105 studies in Osteonecrosis with a site in United States, from their registry updates:
This tab as a report to print or save as PDF → With an account.
The objective of this multi-center study is to collect medium and long-term data on the related clinical complications and functional outcomes of the Pyrocarbon Humeral Head to demonstrate safety and performance, in subjects from the Pyrocarbon IDE Study cohort.
Data collected from this study will support post-market surveillance and MDR requirements as well provide the basis for peer-reviewed publications on mid- and long-term product performance and safety (five to ten years post-op).
Long-term follow-up of Pyrocarbon IDE patients.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Hemi Shoulder Arthroplasty using the Aequalis Pyrocarbon Humeral Head
Change from Baseline to last follow-up visit in ASES scores
ASES Score = American Shoulder and Elbow Surgeons Score, 11 items with total score reported out of 100 measuring pain and activity of patient's evaluated shoulder where lower scores indicate more pain and less function
Time frame: Follow-up visits through 10 years Post-Op
Change from Baseline to last follow-up visit in Constant Murley scores
Combination of physician-completed and patient-reported portions to assess functional state of shoulder including range of motion; total score reported out of 100 measuring where lower scores indicate less function of the evaluated shoulder
Time frame: Follow-up visits through 10 years Post-Op
Change from Baseline to last follow-up visit in SANE scores
SANE = Single Assessment Numeric Evaluation; 1 item assessment of shoulder rating 0% to 100%
Time frame: Follow-up visits through 10 years Post-Op
Change from Baseline to last follow-up visit in Subject Satisfaction scores
Single, subjective question measuring patient satisfaction; assessed by improved, worsened, or no change in satisfaction
Time frame: Follow-up visits through 10 years Post-Op
Change from Baseline to last follow-up visit in EQ-5D scores
The EuroQol Five Dimensions Questionnaire (EQ-5D) questionnaire is a standardized instrument for use as a measure of quality of life. It is cognitively simple, takes only a few minutes to complete, and provides a simple descriptive profile as well as a single index value for quality of life that can be used in the clinical and economic evaluation of health care. The EQ-5D consists of a descriptive system which comprises 5 dimensions (mobility, self care, usual activities, pain/discomfort, anxiety/depression), and a visual analog scale which measures the respondent's self-rated health on a 0-100 scale.
Time frame: Follow-up visits through 10 years Post-Op
Number of device associated and procedure associated adverse events.
Time frame: Follow-up visits through 10 years Post-Op
Evaluation of operated shoulder range of motion
Time frame: Follow-up visits through 10 years Post-Op
Rates of revision surgeries.
Time frame: Follow-up visits through 10 years Post-Op
Plan to share: No
No publications or documents are linked to this record.
Started Oct 2021 (actual). Primary completion is estimated for May 2027, 67 months after the start.
Of 59 observational studies under Osteonecrosis, half reached primary completion within 141 months of starting (the median), counting those still running; a quarter within 93 and three quarters within 184. This study's planned 67 months is below that.
How these figures are worked out, and which studies are left out of them.
This study is active, not recruiting, as verified in Feb 2026. You cannot join it, but the record below documents what was studied.
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Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
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