ClinicalTrials.gg
RecruitingNCT04933370Updated Aug 7, 2024

Neuromodulation Parameter Efficacy

An interventional study of Stimulation parameters in Chronic Pain, sponsored by Alberta Health Services, Calgary. Recruiting at 1 site in Canada. Open to participants aged 18 Years to 100 Years. Per ClinicalTrials.gov, last updated 2024-08-07.

Sponsored by Alberta Health Services, Calgary · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Primary completion was expected by Jul 2026, 4 months ago, but the record still lists the study as recruiting.
  • Started Feb 2022; still recruiting 4 years 9 months later.
Phase
Not applicable
Study type
Interventional
Enrollment
20
Allocation
Randomized
Ages
18 Years to 100 Years
Sex
All
01

Where this study stands

Counted across the records on this site · 2026-11-12

Among 202 studies in Chronic Pain with a site in Canada — 52 open to participants now, 63 under way, 3 of them phase 3. Chronic Pain · Canada.

Planned enrollment
130th of 162
20 · median 49
Started
2022
with 17 others
No phase
116 of 202
31 open now
Primary completion
2026-07
later than 31 of 62 live
Registered
123rd of 202
by date

Among the 202 studies in Chronic Pain with a site in Canada, this one is the 130th largest by planned enrollment of the 162 interventional ones that give a count, is one of 18 that started in 2022, is one of 116 with no phase, reaches primary completion later than 31 of the 62 other live ones, and was the 123rd registered.

Chronic Pain

3,227 studies on the registry are indexed under Chronic Pain; 729 are open to participants now.

Browse Chronic Pain studies →

Open to participants now

52 of the 202 studies in Chronic Pain with a site in Canada are open now. Recruiting first, the newest first:

47 more — sign in →

All 52 open studies →

A study can be open while its sites in Canada have not opened yet or have stopped. Only those recruiting at a site in Canada →

Who these studies take

Of the 486 Chronic Pain studies recruiting now, 239 (49%) set no upper age limit and 173 (36%) stop at 75 or younger; 43 take children under 18; 64 take healthy volunteers.

This study: 18 Years to 100 Years · all sexes · no healthy volunteers.

The full table on the hub →

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02

Study summary

The objective of this study is to determine the efficacy of neuromodulation using various stimulation paradigms in the treatment of several disorders including chronic pain.

Read the detailed description

Different stimulation parameters will be tried in a blinded fashion to compare efficacy.

03

Conditions studied

  • Chronic Pain

Browse trials for

04

Who can participate

Ages eligible
18 Years to 100 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Patients who are candidates for, and have been consented for, implantation of a neuromodulation device.

Exclusion criteria

Exclusion Criteria:

  • Non-English speaking
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Crossover assignment
Masking
Quadruple (Participant, Care provider, Investigator, Outcomes assessor)
Enrollment
20 participants (estimated)

Study arms

  • Active comparator
    Industry standard stimulation

    Industry standard stimulation settings

    Other: Stimulation parameters

  • Sham comparator
    Experimental stimulation

    Experimental stimulation settings

    Other: Stimulation parameters

Interventions

  • OtherStimulation parameters

    Different device stimulation parameters

06

What researchers measure

Primary outcomes

  1. Change in baseline pain measures

    Pain outcomes measured using visual analogue scale

    Time frame: 6 months

Secondary outcomes

  1. Effect of stimulation on quality of life

    As measured using EQ-5D-3L

    Time frame: 6 months

07

Study locations

1 of 1 sites recruiting
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Started Feb 2022 (actual). Primary completion is estimated for Jul 2026, 53 months after the start.

Of 1,295 non-industry interventional studies with no phase under Chronic Pain, half reached primary completion within 20 months of starting (the median), counting those still running; a quarter within 9 and three quarters within 39. This study's planned 53 months is above that.

Counting every sponsor, half of 1,378 studies reached it within 20 months; a quarter within 9 and three quarters within 38.

How these figures are worked out, and which studies are left out of them.

Registered
May 28, 2021
First posted
Jun 21, 2021
StartActual
Feb 1, 2022
Primary completionEst.
Jul 1, 2026
CompletionEst.
Jul 1, 2026
Last update
Aug 7, 2024
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Aug 7, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT04933370
Lead sponsor
Alberta Health Services, Calgary
Responsible party
Fady Girgis (Physician, Alberta Health Services, Calgary) — Principal investigator
First posted
Jun 21, 2021
Start date
Feb 1, 2022
Primary completion
Jul 1, 2026 (estimated)
Completion
Jul 1, 2026 (estimated)
Last update
Aug 7, 2024

Study contacts

Fady Girgis, MD
Contact
fmgirgis@ucalgary.ca
4039446497

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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