An observational study in Postoperative Delirium and Gut Microbiota, sponsored by China Medical University, China. Status unknown at 1 site in China. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2022-10-25.
Sponsored by China Medical University, China · Observational
The study is a case-controlled observational trial. Sixty patients will be divided into 2 groups depending on whether postoperative delirium or not. This study aims to characterise the gut microbiota in patients undergoing gastrointestinal surgery with postoperative delirium. The CAM-ICU (Confusion Assessment Method for Intensive Care Unit) was used for delirium assessment.
The study is a case-controlled observational trial. Sixty patients will be divided into 2 groups depending on whether postoperative delirium or not. This study aims to characterise the gut microbiota in patients undergoing gastrointestinal surgery with postoperative delirium. The CAM-ICU (Confusion Assessment Method for Intensive Care Unit) was used for delirium assessment.
General anesthesia was induced as follows: 0.3 mg kg-1 intravenous (IV) etomidate, 2 mg IV midazolam, 0.4 μg kg-1 IV sufentanil, and 0.2 mg kg-1 IV cisatracurium. Anesthesia was maintained with an end-tidal concentration of 2-3 vol% sevoflurane and 0.2-0.3 μg kg-1h-1 sufentanil to maintain the bispectral index between 40 and 60.
1,057 studies on the registry are indexed under Delirium; 238 are open to participants now.
This study's planned enrollment of 30 is below the median of 200 across 418 observational studies indexed under Delirium.
Browse Delirium studies →China Medical University, China is the lead sponsor of 93 studies on the registry; 34 are open to participants now.
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Patients Undergoing Gastrointestinal Surgery
Exclusion Criteria:
The CAM-ICU (Confusion Assessment Method for Intensive Care Unit) was used for delirium assessment.
Drug: General anesthetic
The CAM-ICU (Confusion Assessment Method for Intensive Care Unit) was used for delirium assessment.
Drug: General anesthetic
General anesthesia was induced as follows: 0.3 mg kg-1 intravenous (IV) etomidate, 2 mg IV midazolam, 0.4 μg kg-1 IV sufentanil, and 0.2 mg kg-1 IV cisatracurium. Anesthesia was maintained with an end-tidal concentration of 2-3 vol% sevoflurane and 0.2-0.3 μg kg-1h-1 sufentanil to maintain the bispectral index between 40 and 60.
Characterisation of Gut Microbiota
this study will characterise gut microbiota in 2 groups of 30 patients
Time frame: from baseline to postoperative 72 hours
This study is status unknown, as verified in Oct 2022. You cannot join it, but the record below documents what was studied.
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China Medical University, China