An interventional study of Binaural Beats Embedded in Old Songs and Old Songs in Mild Cognitive Impairment and Cognitive Function, sponsored by China Medical University, China. Recruiting at 3 sites in China. Open to participants aged 60 Years and older. Per ClinicalTrials.gov, last updated 2026-07-30.
Sponsored by China Medical University, China · Not applicable, Interventional, and Treatment
This study will evaluate whether binaural beats can improve cognitive function in older adults with mild cognitive impairment living in nursing homes. Participants will listen to 10-Hz alpha-frequency binaural beats through headphones once daily for 30 minutes for 14 consecutive days. Cognitive function, sleep quality, anxiety, and depressive symptoms will be assessed before the intervention, after the intervention, and at a 2-week follow-up after the intervention. The study aims to determine whether binaural beats are a safe, simple, and non-drug approach to support cognitive health in older adults with mild cognitive impairment.
3,872 studies on the registry are indexed under Cognitive Dysfunction; 1,119 are open to participants now.
This study's planned enrollment of 60 is close to the median of 64 across 2,794 interventional studies indexed under Cognitive Dysfunction.
Browse Cognitive Dysfunction studies →China Medical University, China is the lead sponsor of 94 studies on the registry; 34 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Withdrawal Criteria:
Removal Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Short tests of memory and thinking, each scored out of 30. Lower scores suggest more difficulty; criteria give a range, either to include people with memory problems or to leave them out.
MMSE and MoCA
Short tests of memory and thinking, each scored out of 30. Lower scores suggest more difficulty; criteria give a range, either to include people with memory problems or to leave them out.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Participants will listen to old songs embedded with 10-Hz alpha-frequency binaural beats through headphones once daily for 30 minutes for 14 consecutive days.
Behavioral: Binaural Beats Embedded in Old Songs
Participants will listen to the same type of old songs without binaural beats through headphones once daily for 30 minutes for 14 consecutive days.
Behavioral: Old Songs
Participants in the intervention group will listen to old songs embedded with 10-Hz alpha-frequency binaural beats through headphones once daily for 30 minutes for 14 consecutive days. The old songs will be selected according to older adults' music preferences.
Participants in the control group will listen to old songs without binaural beats through headphones once daily for 30 minutes for 14 consecutive days. The old songs will be selected according to older adults' music preferences.
Change in Montreal Cognitive Assessment Score
Cognitive function will be assessed using the Montreal Cognitive Assessment. The total score ranges from 0 to 30, with higher scores indicating better cognitive function.
Time frame: Baseline, immediately after the 14-day intervention, and 2 weeks after the intervention
Change in Digit Span Test Score
Time frame: Baseline, immediately after the 14-day intervention, and 2 weeks after the intervention
Change in Stroop Color-Word Test Score
Time frame: Baseline, immediately after the 14-day intervention, and 2 weeks after the intervention
Change in Trail Making Test Score
Time frame: Baseline, immediately after the 14-day intervention, and 2 weeks after the intervention
Change in Pittsburgh Sleep Quality Index Score
Time frame: Baseline, immediately after the 14-day intervention, and 2 weeks after the intervention
Change in Geriatric Anxiety Scale Score
Time frame: Baseline, immediately after the 14-day intervention, and 2 weeks after the intervention
Change in Geriatric Depression Scale-15 Score
Time frame: Baseline, immediately after the 14-day intervention, and 2 weeks after the intervention
Plan to share: Undecided
No publications or documents are linked to this record.
Started Jun 2026 (actual). Primary completion is estimated for Sep 2026, 2 months after the start.
Of 1,442 non-industry interventional studies with no phase under Cognitive Dysfunction, half reached primary completion within 27 months of starting (the median), counting those still running; a quarter within 13 and three quarters within 51. This study's planned 2 months is below that.
Counting every sponsor, half of 1,511 studies reached it within 27 months; a quarter within 12 and three quarters within 50.
How these figures are worked out, and which studies are left out of them.
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China Medical University, China