An interventional study of GPR Intervention Research group in Alzheimer's Type Dementia, Cognitive Decline and Postural; Strain, sponsored by Universidad Católica San Antonio de Murcia. Completed. Open to participants aged 40 Years to 95 Years. Per ClinicalTrials.gov, last updated 2019-11-19.
Sponsored by Universidad Católica San Antonio de Murcia · Not applicable, Interventional, and Treatment
This research study is developed on an experimental design with randomized controlled intervention were participated 135 subjects with AD including 45 of the control group. It lasted 6 months with pre-post tests (T0-T1) executed before and after six months of treatment. By having in focus the evaluation of GPR therapy effects on cognitive, proprioceptive, depressive, autonomy, gait and life quality of the above mentioned subjects.
In order to assess the cognitive abilities of the patients a cognitive test was administered which acts through a scale concerning depression and mood evaluation as well as a questionnaire was developed aiming to evaluate the examined subjects' functional abilities: Mini Mental State Examination (MMSE), Quality of Life in Alzheimer Disease (QoL-AD), geriatric Depression Scale (GDS), Barthel Index (BI), Neuropsychiatric Inventory (NPI), Tinetti Scale (TS).
3,930 studies on the registry are indexed under Cognitive Dysfunction; 1,114 are open to participants now.
This study's enrollment of 135 is above the median of 64 across 2,855 interventional studies indexed under Cognitive Dysfunction.
Browse Cognitive Dysfunction studies →Universidad Católica San Antonio de Murcia is the lead sponsor of 138 studies on the registry; 19 are open to participants now.
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Exclusion Criteria:
A total of 135 subjects with AD in the mild or moderate phase participated in the study from which 90 pertain to research group.The intervention implemented to the patients with AD was the Global Postural therapy which lasted about 30-40 min in repeated sessions of 2 meetings per week by making 48 sessions in total during a six month period.
Other: GPR Intervention Research group
45 subjects of the study belongs to the control group which has not received the same treatment .
The research intervention consisted in the reappointment of three GPR therapeutic postures.
Cognitive Abilities Measurement
The therapeutist provides the Mini Mental State Examination (MMSE) scale records. The evaluation consits in a 0-30 points-scale. Lower scores imply the severity of dementia.
Time frame: Change from baseline cognitive evaluation at 6'th month
Quality of Life in Alzheimer's disease (QoL-AD) Questionnaire
The therapeutist measures in the begining and in the end of the study the quality of life in patients with Alzheimer's disease (QoL-AD). This questionnaire consists in 13 elements referring to the perception that patients have concerning various aspects of their life: mood, health, cognition, environment and functional capacity. The range of scores is 13-52, were higher scores indicate a better life quality.
Time frame: Change from baseline cognitive evaluation at 6'th month
Geriatric Depression Scale (GDS) Questionnaire
The version of 15 articles was used, which given its length can be validly and reliably resolved by patients themselves in the quality of a self-report questionnaire aiming to investigate the possible presence of depressive symptoms.
Time frame: Change from baseline cognitive evaluation at 6'th month
Barthel Index (BI)
This scale is used by therapist to measure the performance in the basic activities of daily life of AD patients. The maximum score used is 100 points and refers to the patient's independence in all basic daily living activities.
Time frame: Change from baseline cognitive evaluation at 6'th month
Neuropsychiatric Inventory (NPI)
This test includes 12 symptoms scored according to the phenomenon severity and frequency. It is a helpful instrument for the therapist because of specifically designed for the assessment of psycho-behavioral disorders in individuals with cognitive impairment.
Time frame: Change from baseline cognitive evaluation at 6'th month
Tinetti Scale (TS)
The therapist used the equilibrium sub-scale, which consists in 7 elements and has a score between 0 and 13. Highest scores indicate a better balance.
Time frame: Change from baseline cognitive evaluation at 6'th month
No study locations are listed for this record.
Plan to share: No — All participants signed the informed consent and their family members were also informed concerning the purpose of the study. Correspondingly the data were provided by the physiotherapists who performed the above mentioned technique. Thereafter the study was validated and approved by the Ethics Committee of Catholic University of Murcia.
This study is completed, as verified in Nov 2019. You cannot join it, but the record below documents what was studied.
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