An interventional study of Short duration and Long duration in Diabetes, sponsored by Hacettepe University. Completed at 1 site in Turkey. Open to participants aged 18 Years to 64 Years. Per ClinicalTrials.gov, last updated 2020-04-09.
Sponsored by Hacettepe University · Not applicable, Interventional, and Treatment
Aim: To assess whether there are different training effects on glucose concentration and cardiorespiratory parameters of different high-intensity training protocols in patients with type 2 diabetes.
Type 2 diabetes is a highly prevalent disease associated with cardiovascular disease leading to high levels of mortality, morbidity and health expenditure, characterized by impaired glucose control during activities and reduced aerobic exercise capacity .
Exercise training is the most effective way to improve compliance, reduce blood glucose concentration and increase insulin sensitivity. Training increases muscle capacity, oxidative capacity and glucose transport, peripheral insulin sensitivity is improved.
Exercise training with high-intensity interval (resting and exercise period) High Intensity Interval Training (HIIT) is a form of exercise training that has recently been widely used in the management of type 2 diabetes, including short duration high intensity exercise periods and lower severity or passive rest periods. There are different HIIT exercise training programs according to physiological responses in the literature. However, long-term and short-term HIIT training training programs were not compared in terms of their effect on glucose concentration and cardiorespiratory fitness. The aim of this study was to compare the effects of different HIIT exercise training programs so that exercise programs for patients with type 2 diabetes could be planned more effectively.
This study will be participated patients with Type 2 diabetes. Patients' laboratory values, pulmonary function test, respiratory muscle strength, exercise capacity, physical activity level, quality of life will be evaluated.
Pulmonary function test will be assesed with spirometer, respiratory muscle strength will be evaluated with mouth pressure. Exercise capacity will be evaluated using six minute walking test, incremental shuttle walk test, cycle ergometer. Muscle oxigeneration will be asssed with wearable lactate threshold predicting device. Physical activity level will be evaluated trial accelerometer.
Then, patients will be randomly divided two high intensity interval exercise training groups.
First group: short duration high intensity exercise training (Exercise load phase : 30sn %100 Patients performance, rest phase: 120sn %25 patients performance) Second group: Long duration high intensity interval exercise training (Exercise load phase : 4 dk %100 Patients performance, rest phase: 120sn %25 patients performance) All patients will participate three times a week during eight weeks. The muscle oxigeneration, blood glucose consantration, blood pressure, heart rate will be recorded before and after each exercise session. After 8 week, all test will be done again.
Exclusion Criteria:
Individuals have known lung disease,have undergone any cardiac event or surgery within the past six months, have uncontrolled hypertension, and have diabetic complications such as nephropathy, retinopathy and severe neuropathy.
30sn %100 Wmax 120sn %25 Wmax 3 sessions/week total 8 weeks
Other: Short duration
4dk %85 Wmax 120sn %25 Wmax 3 sessions/week total 8 weeks
Other: Long duration
exercise Short duration high intensity training
Also known as: training
exercise Long duration high intensity training
Also known as: training
muscle oxigeneration
It is evaluate with wearable lactate threshold device on gastrocinemius
Time frame: Change from baseline muscle oxigeneration at 8 weeks
The blood glucose consentration
It is evaluate with sample from blood
Time frame: before and after 8 weeks
Functional Exercise capacity
İt is evaluated with six minute walk test
Time frame: before and after 8 weeks
Maximal exercise capacity
İt is evaluated using with incremental shuttle test
Time frame: before and after 8 weeks
Symptom limited maximal exercise capacity
İt is evaluated with cycle ergometer test
Time frame: before and after 8 weeks
Lipit profile-High density lipoprotein cholesterol
High density lipoprotein cholesterol wiil be assesed
Time frame: before and after 8 weeks
Lipit profile- low density lipoprotein cholesterol
low density lipoprotein cholesterol wiil be assesed
Time frame: before and after 8 weeks
Lipit profile- trigliseride
trigliseride wiil be assesed
Time frame: before and after 8 weeks
pulmonary parameter-Forced vital capacity
Forced vital capacity will be evaluated
Time frame: before and after 8 weeks
pulmonary parameter-Forced vital capacity in the first second
Forced vital capacity in the first second will be evaluated
Time frame: before and after 8 weeks
pulmonary parameter-Mid expiratory flow rate
Mid expiratory flow rate will be evaluated
Time frame: before and after 8 weeks
pulmonary parameter-Peak expiratory flow
Peak expiratory flow will be evaluated
Time frame: before and after 8 weeks
Respiratory muscle strength
It is evaluated with mouth pressure
Time frame: before and after 8 weeks
Physical activity level
ıt is assessed using accelerometer
Time frame: before and after 8 weeks
This study is completed, as verified in Apr 2020. You cannot join it, but the record below documents what was studied.
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Hacettepe University