An observational study in Multiple Sclerosis, sponsored by Hacettepe University. Recruiting at 1 site in Turkey (Türkiye). Open to participants aged 10 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-09-17.
Sponsored by Hacettepe University · Observational
Among 23 studies in Multiple Sclerosis by Hacettepe University — 6 open to participants now, 6 under way, none of them phase 3. Multiple Sclerosis · Hacettepe University.
Among the 23 studies in Multiple Sclerosis by Hacettepe University, this one is one of 3 that started in 2025, is one of 8 observational ones, and was the 15th registered.
3,264 studies on the registry are indexed under Multiple Sclerosis; 659 are open to participants now.
This study's planned enrollment of 50 is below the median of 100 across 970 observational studies indexed under Multiple Sclerosis.
Browse Multiple Sclerosis studies →6 of the 23 studies in Multiple Sclerosis by Hacettepe University are open now, in 1 country. Each count lists the studies.
Of the 430 Multiple Sclerosis studies recruiting now, 163 (38%) set no upper age limit and 211 (49%) stop at 75 or younger; 40 take children under 18; 96 take healthy volunteers.
This study: 10 Years and older · all sexes · healthy volunteers too.
The full table on the hub →23 studies; the count open now beside each. This study's row is marked.
First in 2015; this study’s year is marked. 3 started in 2025.
Median enrollment 34 across the 15 interventional studies, 56 across the 8 observational. Of the 13 that completed or were terminated, 0 (0%) have results posted.
Hacettepe University is the lead sponsor of 1,007 studies on the registry; 214 are open to participants now.
4 of the studies in Multiple Sclerosis by Hacettepe University that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07137624Hacettepe UniversityMotor Imagery and Action Observation for Gait Function in MS | 2026-11 |
| NCT07151534Hacettepe UniversityBody Awareness, Trunk Stability, and Arm Function in MS | 2026-12-31 |
| NCT07786987Hacettepe UniversityCone Evasion Walk Test in Multiple Sclerosis | 2027-06-30 |
| NCT07899411Hacettepe UniversityEvaluation of the Effect of Mental Imagery Training Combined With Modified Constraint-Induced Movement Therapy in Individuals With Multiple Sclerosis | 2027-10 |
Among the 23 studies in Multiple Sclerosis by Hacettepe University, from their registry updates:
The aim of this study is to investigate the relationship between body awareness, trunk stabilization, and upper extremity functionality in patients with Multiple Sclerosis (MS).
Hypotheses of the study:
H1: There is a significant relationship between body awareness and upper extremity functionality in patients with MS.
H2: There is a significant relationship between body awareness and trunk stabilization in patients with MS.
H3: Body awareness is reduced in patients with MS compared to healthy individuals.
H4: Trunk stabilization is reduced in patients with MS compared to healthy individuals.
H5: Upper extremity functionality is reduced in patients with MS compared to healthy individuals.
Patients' demographic and disease-specific information will be recorded. Subsequently, body awareness, upper extremity functionality, and trunk stabilization will be assessed.
MS patients and healthy subjects with inclusion criteria
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
(MMSE) score ≥ 24
Exclusion Criteria:
Refusing to participate or not providing written
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Short tests of memory and thinking, each scored out of 30. Lower scores suggest more difficulty; criteria give a range, either to include people with memory problems or to leave them out.
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
MMSE and MoCA
Short tests of memory and thinking, each scored out of 30. Lower scores suggest more difficulty; criteria give a range, either to include people with memory problems or to leave them out.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Corticosteroids (steroids)
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Diagnosed with Multiple Sclerosis (MS) by a neurologist according to the McDonald criteria, aged 18 years or older, Expanded Disability Status Scale (EDSS) score of ≤ 5, Mini-Mental State Examination score of 24 or higher will be included in the study.
A control group consisting of healthy individuals matched with MS patients by age and sex will be included in the study.
Body Awareness Questionnaire
To assess body awareness, the Body Awareness Questionnaire will be used.This questionnaire consists of 18 items, each scored on a scale from 1 to 7, and evaluates body awareness. Higher scores indicate better body awareness. The Turkish version has been validated and found to be reliable.
Time frame: up to 6 months
Body Awareness Rating Questionnaire
To assess body awareness,the Body Awareness Rating Questionnaire will be used. Body Awareness Rating Questionnaire:This questionnaire includes 24 items across 4 domains: function, mood, feeling/sensation, and awareness. Higher scores indicate better body awareness. The Turkish version has been validated and shown to be reliable.
Time frame: up to 6 months
Upper Extremity Functionality-Grip strength
Grip strength will be measured with a Jamar dynamometer. It will be performed three times bilaterally, and average values (kg) will be recorded.
Time frame: up to 6 months
Upper Extremity Functionality-Pinch strength
Pinch strengths will be assessed using a Baseline pinch gauge. It will be performed three times bilaterally, and average values (kg) will be recorded.
Time frame: up to 6 months
Upper Extremity Functionality-Nine Hole Peg Test (9HPT)
The 9HPT will evaluate hand dexterity by timing how quickly participants place and remove nine pegs. Each hand will be tested three times. It will be recorded in seconds. An average time ≥33.3 seconds will indicate dysfunction in MS patients.
Time frame: up to 6 months
Trunk Stabilization- Trunk Impairment Scale (TIS),
Trunk stabilization will be evaluated using the TIS.TIS: Assesses static/dynamic balance and trunk coordination (17 items, 0-23 points).
Time frame: up to 6 months
Trunk Stabilization-plank endurance test
Trunk stabilization will be evaluated using the plank endurance test. The test measures core endurance. Plank test: Time held in forearm plank recorded. It will be recorded in seconds.
Time frame: up to 6 months
Trunk Stabilization-side bridge test
Trunk stabilization will be evaluated using the side bridge test. The test measures core endurance Time held in side plank on both sides recorded.It will be recorded in seconds.
Time frame: up to 6 months
Trunk Stabilization-Modified Biering-Sorensen
Trunk stabilization will be evaluated using the Modified Biering-Sorensen test. The test measures core endurance. Time holding trunk in horizontal position prone over table edge. It will be recorded in seconds.
Time frame: up to 6 months
Trunk Stabilization-Trunk flexor test
Trunk stabilization will be evaluated using the Trunk flexor test test.The test measures core endurance. Time maintaining 60° trunk flexion with knees/hips at 90°. It will be recorded in seconds.
Time frame: up to 6 months
Trunk Stabilization-Sit up test
The 30-second Sit-up Test measures core strength. The person lies on their back with knees bent and feet on the floor. They do as many sit-ups as possible in 30 seconds, keeping proper form. The score is the number of correct sit-ups completed.
Time frame: up to 6 months
Trunk Stabilization-Modifiye push up test
The 30-second Modified Push-up Test measures core strength. The person starts in a push-up position but with knees on the floor. They perform as many push-ups as possible in 30 seconds, keeping the body straight and lowering the chest close to the ground. The score is the number of correct push-ups completed.
Time frame: up to 6 months
Plan to share: No
No publications or documents are linked to this record.
Started Aug 2025 (actual). Primary completion is estimated for Dec 2026, 16 months after the start.
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