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Status unknownNCT03474601SNU-PITUpdated Mar 18, 2020

Seoul National University Pituitary Disease Cohort Study

An observational study in Pituitary Disease, Pituitary Incidentaloma and Acromegaly, sponsored by Seoul National University Hospital. Status unknown at 1 site in Korea, Republic of. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2020-03-18.

Sponsored by Seoul National University Hospital · Observational

The sponsor has not verified this record recently (last verified Mar 2019), so the status shown — last known as Recruiting — may be out of date.
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
1,600
Ages
18 Years and older
Sex
All
01

Study summary

The purpose of this study is to investigate the treatment and natural history of pituitary disease. We have a longstanding interest in pituitary disease including acromegaly, central diabetes insipidus, and nonfunctioning pituitary adenoma. We will continue to follow patients and recruit new patients for treatment and follow-up. Blood and pituitary tumor tissue (when available through clinical care) will be saved for future analyses related to pituitary disease.

Read the detailed description

Subjects for this study will be recruited if they are:

  1. Adults, male or female aged 18 years or older
  2. Have been diagnosed with pituitary diseases
02

Conditions studied

  • Pituitary Disease
  • Pituitary Incidentaloma
  • Acromegaly
  • Central Diabetes Insipidus
  • Pituitary Stalk Compression Hyperprolactinaemia
  • Cushing's Disease
  • Pituitary Tumor
  • Prolactinoma

Keywords

  • Pituitary Diseases
  • Pituitary incidentaloma
  • Central Diabetes Insipidus
  • Pituitary Neoplasms
03

In context

Pituitary Diseases

74 studies on the registry are indexed under Pituitary Diseases; 15 are open to participants now.

This study's planned enrollment of 1,600 is above the median of 292 across 31 observational studies indexed under Pituitary Diseases.

Browse Pituitary Diseases studies →

Lead sponsor

Seoul National University Hospital is the lead sponsor of 1,900 studies on the registry; 274 are open to participants now.

Of its 12 completed or terminated interventional studies of FDA-regulated products, 2 (17%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients diagnosed with pituitary disease at Seoul National University Hospital

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Subjects for this study will be recruited if they are:

    1. Adults, male or female aged 18 years or older
    2. diagnosed with pituitary diseases such as acromegaly, Cushing's disease, hyperprolactinemia, nonfunctioning pituitary adenoma, pituitary stalk lesions, central diabetes insipidus, and craniopharyngiomas

Exclusion criteria

Exclusion Criteria:

  • Patients who do not agree with the study
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
1,600 participants (estimated)
Patient registry
No
Biospecimen retention
Samples without dna

Groups and cohorts

  • Acromegaly

    Patients diagnosed with acromegaly

    Other: Dynamic hormone study and Magnetic resonance imaging

  • Cushing's disease

    Patients diagnosed with Cushing's disease

    Other: Dynamic hormone study and Magnetic resonance imaging

  • Hyperprolactinemia/prolactinomas

    Patients diagnosed with hyperprolactinemia/prolactinoma

    Other: Dynamic hormone study and Magnetic resonance imaging

  • Pituitary stalk lesions

    Patients diagnosed with pituitary stalk lesions

    Other: Dynamic hormone study and Magnetic resonance imaging

  • Nonfunctioning pituitary adenomas

    Patients diagnosed with nonfunctioning pituitary adenomas

    Other: Dynamic hormone study and Magnetic resonance imaging

  • Central diabetes insipidus

    Patients diagnosed with central diabetes insipidus

    Other: Dynamic hormone study and Magnetic resonance imaging

  • Craniopharyngioma

    Patients diagnosed with craniopharyngiomas

    Other: Dynamic hormone study and Magnetic resonance imaging

  • Others

    Patients diagnosed with other suprasellar/parasellar lesions

    Other: Dynamic hormone study and Magnetic resonance imaging

Interventions

  • OtherDynamic hormone study and Magnetic resonance imaging

    1. Medical history 2. Imaging examination including brain magnetic resonance imaging 3. Blood (Basal hormone study and follow-up study) and pituitary tumor tissue

06

What researchers measure

Primary outcomes

  1. Treatment outcome of pituitary diseases

    Remission rate

    Time frame: Up to 10 years

Secondary outcomes

  1. Complications of pituitary disease

    Visual field defect or hypopituitarism, hormone hyperfunction-related complications

    Time frame: Up to 10 years

07

Study locations

1 of 1 sites recruiting
  • Seoul National University Hospital
    Seoul, 03080, Korea, Republic of
    Recruiting
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 18, 2020, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT03474601
Responsible party
Jung Hee Kim (Principal Investigator, Seoul National University Hospital) — Principal investigator
First posted
Mar 22, 2018
Start date
Mar 15, 2015
Primary completion
Feb 14, 2025 (estimated)
Completion
Feb 14, 2025 (estimated)
Last update
Mar 18, 2020

Study contacts

Jung Hee Kim, M.D
Contact
jhkxingfu@gmail.com
82-2-2072-4073
Jung Hee Kim, M.D
principal investigator · Seoul National University Hospital

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Mar 2019. You cannot join it, but the record below documents what was studied.

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