An interventional study of Dynamic light and Standard in Depression, Light; Therapy, Complications and Sleep Disorders, Circadian Rhythm, sponsored by University Hospital Bispebjerg and Frederiksberg. Completed at 1 site in Denmark. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-02-25.
Sponsored by University Hospital Bispebjerg and Frederiksberg · Not applicable, Interventional, and Treatment
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Among 124 studies in Depression with a site in Denmark — 14 open to participants now, 17 under way, none of them phase 3. Depression · Denmark.
Among the 124 studies in Depression with a site in Denmark, this one is the 89th largest by enrollment of the 92 interventional ones that give a count, is one of 9 that started in 2017, is one of 69 with no phase, and was the 70th registered.
8,582 studies on the registry are indexed under Depression; 1,723 are open to participants now.
Browse Depression studies →14 of the 124 studies in Depression with a site in Denmark are open now. Recruiting first, the newest first:
Aalborg University Hospital · Sites in Denmark
Ages 18–65
Zealand University Hospital · Sites in Denmark
Ages 18+
Nordsjaellands Hospital · Sites in Denmark
Ages 18–65
Aalborg University Hospital · Sites in Denmark
Ages 18–65
University of Southern Denmark · Sites in Denmark
Ages 18+
A study can be open while its sites in Denmark have not opened yet or have stopped. Only those recruiting at a site in Denmark →
Of the 1,089 Depression studies recruiting now, 470 (43%) set no upper age limit and 519 (48%) stop at 75 or younger; 203 take children under 18; 311 take healthy volunteers.
This study: 18 Years and older · all sexes · no healthy volunteers.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
124 studies; the count open now beside each. This study's row is marked.
A study in two phases is counted once above. Listed by phase, each with its combined phases: Phase 1 2 · Phase 2 8 · Phase 3 7 · Phase 4 9
First in 2003; this study’s year is marked. 9 started in 2017.
By drug class, each counting the studies that test any of its medicines:
This study's enrollment of 15 is below the median of 81 across 7,066 interventional studies indexed under Depression.
Median enrollment 139 across the 92 interventional studies, 136 across the 32 observational. Of the 91 that completed or were terminated, 5 (5%) have results posted.
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2 of 124 have an industry lead sponsor. The 10 most frequent:
University Hospital Bispebjerg and Frederiksberg is the lead sponsor of 69 studies on the registry; 18 are open to participants now.
University Hospital Bispebjerg and Frederiksberg has 4 studies filed under Depression — fewer than ten, so there is no comparison to draw.
7 of the studies in Depression with a site in Denmark that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07180407Zealand University HospitalThe Post-ICU Pain Study | 2027-01 |
| NCT06782724University Medical Center GroningenPsilocybin Therapy for Psychological Distress in Palliative Patients | 2027-01-01 |
| NCT06919133Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg HospitalThe Effect of Digital Markers in the Self-management of Depressive Symptoms | 2027-05-01 |
| NCT07080723Aalborg University HospitalAlgorithm Guided Treatment Versus Treatment as Usual (TAU) for Patients With Treatment Resistant Depression | 2027-06 |
| NCT06097221University Hospital Bispebjerg and FrederiksbergThe Advance Project - Advancing Sleep Timing to Improve Depression | 2027-06 |
Add all 7 to your calendar (.ics) → With an account.
Among the 124 studies in Depression with a site in Denmark, from their registry updates:
This tab as a report to print or save as PDF → With an account.
Depression is a major health challenge, and despite developments in pharmacotherapy and psychotherapy a substantial part of patients will only recover very slowly and incompletely, and 10-25 % of the patients are resistant to treatment. Therefore, new treatment initiatives are in demand. Chronotherapeutics can regulate diurnal rhythms and sleep, and have shown promising results on antidepressant effects. Among chronotherapeutic treatment modalities, Bright Light Therapy (BLT) has been used in treatment of depression and sleep disorders for several decades with both an antidepressant and a sleep improving effect. BLT has also been shown to augment antidepressant therapy.
Objectives. The objective of this trial is to investigate the feasibility of a combination of LED-light armatures aiming to mimic sunlight, when installed in the patient rooms of a psychiatric inpatient Ward. Investigators has opted for using a randomized design that will subsequently be tested in a larger clinical trial with depression severity as the primary outcome. In this feasibility study investigators will register the stability of the system, the influence of the light on patients regarding tolerability, comfort, depression level, and sleep. Investigators also so want to measure and collect specific light-data on the Non-image-forming light (NIF) by using specially designed light sensors to capture the spectral distribution of the light. Finally investigators will test the electronic case report form (eCRF) that has been designed for the trial.
Design. The design is a randomised controlled feasibility trial with two arms: an active dynamic light trial arm and a standard light trial arm with blinding of depression outcome assessors (Hamilton depression rating scale), data collection, and data analyses. Randomization will be with a rate for active and standard of 2 to 1.
Inclusion and exclusion criteria. Inclusion: Major depression disorder, age > 18 years, informed consent and Danish speaking.
Exclusion: Severe suicidality, actual psychotic state, bipolar disorder and if the patient is subject to coercive measures of any kind.
Name and description of experimental and control intervention. The experimental intervention is the implementation of a dynamic LED-light system in two patient rooms. The system includes three elements: a window jamb built-in light panel, two ceiling mounted lamps, and a wall mounted lamp. All lamps will have a dynamic, time dependent frequency distribution and intensity of light. The control intervention is constant standard LED-light with two elements: two ceiling mounted lamps and a wall mounted lamp.
Primary and secondary outcomes.
Primary outcome:
1. Rate of patients discontinuing the trial due to discomfort from the lighting condition.
Secondary outcomes:
Time schedule. The first participant is expected to be enrolled in December 2017. The expected last follow-up of the last participant will be June 2018. Data will be analysed from June 2018 till December 2018. Manuscripts will be prepared from June 2017 and we expect to submit first manuscript January 2019.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
This study arm utilizes a standard lighting condition in the patient room
Device: Standard
This study arm utilizes a dynamic lighting from special designed lightfixtures in the ceiling and window sill.
Device: Dynamic light
Dynamic lighting is light that changes in intensity and spectral distribution during the day
Standard lighting is non-dynamical light corresponding to standard hospital lighting.
Difference in numbers of drop out in the two groups
Number of patients in the two groups that drop out due to the standard or experimental lighting condition
Time frame: Week 4
Visual comfort questionaire
Difference in scores in the Visual comfort questionaire
Time frame: Week 4
Change of depression level from baseline to endpoint
Difference in change scores on the Hamilton Depression Rating scale 17 item from baseline to week 4 in the two groups
Time frame: Change scores from baseline to week 4
Plan to share: No
Ran from Nov 2017 to primary completion in Dec 2018, 13 months.
Of 3,471 non-industry interventional studies with no phase under Depression, half reached primary completion within 21 months of starting (the median), counting those still running; a quarter within 10 and three quarters within 41. This study's 13 months is below that.
Counting every sponsor, half of 3,569 studies reached it within 21 months; a quarter within 9 and three quarters within 41.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Feb 2026. You cannot join it, but the record below documents what was studied.
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University Hospital Bispebjerg and Frederiksberg