ClinicalTrials.gg
Not yet recruitingNCT07934784MITSUpdated Nov 13, 2026

The Mother-infant Touch Study

An interventional study of Physical touch in Depression, sponsored by Yale University. Not yet recruiting at 1 site in United States. Open to female participants aged 21 Years to 45 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-11-13.

Sponsored by Yale University · Not applicable, Interventional, and Basic science

Updated Nov 13, 2026Newly registeredGo to Updates ↓

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Phase
Not applicable
Study type
Interventional
Enrollment
60
Allocation
Not applicable
Ages
21 Years to 45 Years
Sex
Female
01

Where this study stands

Counted across the records on this site · 2026-11-13

Among 60 studies in Depression by Yale University — 7 open to participants now, 9 under way, 1 of them phase 3. Depression · Yale University.

Planned enrollment
25th of 52
60 · median 51
Started
2026
with 2 others
No phase
35 of 60
4 open now
Registered
60th of 60
by date

Among the 60 studies in Depression by Yale University, this one is the 25th largest by planned enrollment of the 52 interventional ones that give a count, is one of 3 that started in 2026, is one of 35 with no phase, and was the 60th registered.

Depression

8,582 studies on the registry are indexed under Depression; 1,723 are open to participants now.

Browse Depression studies →

Open to participants now

7 of the 60 studies in Depression by Yale University are open now, in 2 countries. Recruiting first, the newest first:

1 more — sign in →

By country, each count listing its studies:

All 7 open studies →

Who these studies take

Of the 1,089 Depression studies recruiting now, 470 (43%) set no upper age limit and 519 (48%) stop at 75 or younger; 203 take children under 18; 311 take healthy volunteers.

This study: 21 Years to 45 Years · female · healthy volunteers too.

The full table on the hub →

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Watch this landscapeDownload CSVNarrow it in search →With an account: a weekly mail of what changed among 60 studies in Depression by Yale University, or all of them as a file.
02

Study summary

The purpose of this research study is to learn more about mother-infant interactions, including how infants experience different types of touch.

03

Conditions studied

  • Depression

Browse trials for

04

Who can participate

Ages eligible
21 Years to 45 Years
Sexes eligible
Female
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Mothers aged 21-45 years of infants aged 4-6 months
  • English-speaking
  • Able to provide

Exclusion criteria

Exclusion Criteria:

  • Mothers of infants who have severe health or developmental disorders;
  • Mothers evidencing the presence of severe psychiatric symptoms (e.g., disorganized speech, reporting delusions)
  • Persons incapable of giving
  • Mothers reporting recent substance use as determined by the ASI Lite
  • Mothers of infants who present with neurological impairments (e.g., epilepsy/seizures)
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Informed consent

Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.

You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.

05

Study design

Phase
Not applicable
Primary purpose
Basic science
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
60 participants (estimated)

Study arms

  • Experimental
    Experimental Task

    All infant participants will receive CT-optimal touch, non-CT optimal touch, and no stroking touch condition

    Other: Physical touch

Interventions

  • OtherPhysical touch

    All infant participants will receive CT-optimal touch, non-CT optimal touch, and no stroking touch condition

06

What researchers measure

Primary outcomes

  1. Infant heart-evoked potentials

    The amplitude of infant heart-evoked potentials will be examined as a function of the experimental touch condition (CT optimal touch, non-CT optimal touch, and non stroking touch).

    Time frame: During experimental task on the study visit day (1 day)

  2. Infant heart rate

    Infant heart rate will be examined as a function of the experimental touch condition (CT optimal touch, non-CT optimal touch, and non stroking touch).

    Time frame: During experimental task on the study visit day (1 day)

07

Study locations

1 site
  • Yale Child Study Center
    New Haven, Connecticut 06520, United States
08

References and documents

Individual participant data

Plan to share: Yes — IPD to be shared (all de-identified): Infant EEG and ECG Data Maternal Self-Reported Questionnaire and Interview Data Quantitative scores from behavioral coding of video recordings of infants and mother-infant interactions Infant tactile sensitivity

Time frame: At the time of publication

Access criteria: Data will be made available on OpenNeuro and Open Science Framework

No publications or documents are linked to this record.

09

Timeline

1 registry update since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Start is estimated for Dec 2026; primary completion for Aug 2028, 20 months later.

Of 3,471 non-industry interventional studies with no phase under Depression, half reached primary completion within 21 months of starting (the median), counting those still running; a quarter within 10 and three quarters within 41. This study's planned 20 months is close to that.

Counting every sponsor, half of 3,569 studies reached it within 21 months; a quarter within 9 and three quarters within 41.

How these figures are worked out, and which studies are left out of them.

Registered
Nov 6, 2026
First posted
Nov 13, 2026
StartEst.
Dec 2026
Primary completionEst.
Aug 2028
CompletionEst.
Aug 2028
Last update
Nov 13, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
Registered
First appeared on the registry. No changes since
Nov 13, 2026
Show all 1 update
  1. Nov 13, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07934784
Lead sponsor
Yale University
Responsible party
Sponsor
First posted
Nov 13, 2026
Start date
Dec 2026 (estimated)
Primary completion
Aug 2028 (estimated)
Completion
Aug 2028 (estimated)
Last update
Nov 13, 2026

Study contacts

Helena Rutherford, PhD
Contact
helena.rutherford@yale.edu
203-737-3408
Helena Rutherford, PhD
principal investigator · Yale University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Nov 2026. You cannot join it, but the record below documents what was studied.

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Discussion

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