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CompletedNCT03344224Updated Jan 4, 2018

Pre-operative Blood Lipid Level and Post-operative Major Adverse Cardiac Event

An observational study in Lipid Metabolism Disorders and Postoperative Complications, sponsored by Peking University First Hospital. Completed. Open to participants aged 18 Years to 100 Years. Per ClinicalTrials.gov, last updated 2018-01-04.

Sponsored by Peking University First Hospital · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
50,000
Ages
18 Years to 100 Years
Sex
All
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Study summary

Whether the pre-operative blood lipid level and post-operative cardiovascular events is associated is unknown. This study is to find out the main blood lipid and relative protein level change and the post-operative cardiovascular events occurrence.

Read the detailed description

The participants collected data from their hospital.Patients under going non-cardiac surgery were collected. Data of Triglycerides, cholesterol, Low-density lipoprotein and High-density lipoprotein were collected perioperatively. The postoperative major cardiovascular and cerebral events were also identified and collected. Other data including perioperative information and surgeries and anesthesia data were gathered.

Logistic regression models were built and selected. Independent risk factors relative to postoperative major cardiovascular and cerebral events were screened and identified. different levels of Triglycerides, cholesterol, Low-density lipoprotein and High-density lipoprotein were analysed.

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Conditions studied

03

Who can participate

Ages eligible
18 Years to 100 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

adult non-cardiac surgery patients

Inclusion criteria

  • non-cardiac surgery patients with preoperative blood lipid tests

Exclusion criteria

Exclusion Criteria:

  • electronic records missing or peri-operative data missing
04

Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
50,000 participants (actual)
Patient registry
No

Groups and cohorts

  • normal blood lipid/protein group

    Diagnostic Test: laboratory test

  • abnormal blood lipid/protein group

    Diagnostic Test: laboratory test

Interventions

  • Diagnostic testlaboratory test

    laboratory test

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What researchers measure

Primary outcomes

  1. cardiovascular events

    such as acute myocardial infarction

    Time frame: 30 days postoperatively

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Study locations

No study locations are listed for this record.

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References and documents

Publications

  • Leardi S, Altilia F, Delmonaco S, Cianca G, Pietroletti R, Simi M. [Blood levels of cholesterol and postoperative septic complications]. Ann Ital Chir. 2000 Mar-Apr;71(2):233-7. Italian. PubMed 10920496 ↗
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Registry details

Key details

Study ID
NCT03344224
Lead sponsor
Peking University First Hospital
Responsible party
Yan Zhou, MD (Principal Investigator,, Peking University First Hospital) — Principal investigator
First posted
Nov 17, 2017
Start date
Jan 1, 2017
Primary completion
Jul 30, 2017
Completion
Sep 20, 2017
Last update
Jan 4, 2018

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jan 2018. You cannot join it, but the record below documents what was studied.

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