ClinicalTrials.gg
WithdrawnNCT03254680Updated Apr 30, 2018

Turmeric as Treatment in Epilepsy

An interventional study of Turmeric in Epilepsy, Dravet Syndrome and Lennox-Gastaut Syndrome, sponsored by NYU Langone Health. Withdrawn at 1 site in United States. Open to participants aged 1 Year to 70 Years. Per ClinicalTrials.gov, last updated 2018-04-30.

Sponsored by NYU Langone Health · Not applicable, Interventional, and Treatment

Why this study was withdrawn
Funding
Phase
Not applicable
Study type
Interventional
Enrollment
0
Allocation
Not applicable
Ages
1 Year to 70 Years
Sex
All
01

Where this study stands

Counted across the records on this site · 2026-11-12

Among 24 studies in Epilepsy by NYU Langone Health — 5 open to participants now, 6 under way, none of them phase 3. Epilepsy · NYU Langone Health.

Enrollment
17th of 21
0 · median 15
Started
2018
the only one that year
No phase
16 of 24
4 open now
Registered
20th of 24
by date

Among the 24 studies in Epilepsy by NYU Langone Health, this one is the 17th largest by enrollment of the 21 interventional ones that give a count, is the only one that started in 2018, is one of 16 with no phase, and was the 20th registered.

Epilepsy

1,848 studies on the registry are indexed under Epilepsy; 422 are open to participants now.

Browse Epilepsy studies →

Open to participants now

5 of the 24 studies in Epilepsy by NYU Langone Health are open now, in 1 country. Each count lists the studies.

All 5 open studies →

Where they have run

Who these studies take

Of the 285 Epilepsy studies recruiting now, 113 (40%) set no upper age limit and 149 (52%) stop at 75 or younger; 139 take children under 18; 56 take healthy volunteers.

This study: 1 Year to 70 Years · all sexes · no healthy volunteers.

The full table on the hub →
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Watch this landscapeDownload CSVNarrow it in search →With an account: a weekly mail of what changed among 24 studies in Epilepsy by NYU Langone Health, or all of them as a file.
02

Study summary

This is a single center open-label pilot clinical trial of patients 1-70 years of age with greater than 6 seizures per month diagnosed with Dravet Syndrome, Lennox-Gastaut Syndrome, Tuberous Sclerosis, or focal seizures. Twenty patients will be enrolled and treated with a stable dose of orally administered turmeric oil daily for 3 months. Patients and caregivers will be asked to keep a seizure diary logging all clinical events during the course of the study. Serum comprehensive metabolic panel, complete blood count with differential, and antiseizure medication levels, will be monitored at baseline, 1.5 months, and at the end of 3 months.

03

Conditions studied

  • Epilepsy
  • Dravet Syndrome
  • Lennox-Gastaut Syndrome
  • Tuberous Sclerosis
  • Focal Seizures

Keywords

  • Turmeric Oil
  • antiseizure medications
  • ar-turmerone
04

Who can participate

Ages eligible
1 Year to 70 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Patients with greater than greater than six seizures per month diagnosed with Dravet Syndrome, Lennox-Gastaut Syndrome, Tuberous Sclerosis, or focal seizures followed at NYU CEC.

Exclusion criteria

Exclusion Criteria:

  • Patients expected to have changes to any medications or supplements during study period
  • exposure to any agent in the month prior to study entry
  • pregnant or breast feeding women, positive pregnancy test
  • history of non-compliance
  • known drug or alcohol dependence
  • known baseline hematologic
  • liver function
  • renal function
  • absorption
  • absorption
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Investigational drug or device

A drug or device being studied in a clinical trial.

It may be new, or already approved and being studied for another use, dose or form. Criteria often leave out people who took part in another study of one within a recent period, commonly 30 days or five half-lives.

05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
0 participants (actual)

Study arms

  • Experimental
    Turmeric Oil

    stable dose of orally administered turmeric oil

    Dietary Supplement: Turmeric

Interventions

  • Dietary supplementTurmeric

    Drug pages: Turmeric extract · Curcuma longa

    Twenty patients will be enrolled and treated with a stable dose of orally administered turmeric oil daily for 3 months.

06

What researchers measure

Primary outcomes

  1. Number of epilepsy patients enrolled in study

    feasibility of recruiting patients into a prospective study designed to evaluate the effect of orally ingested turmeric oil on seizures.

    Time frame: 3 months

Secondary outcomes

  1. Number of epilepsy seizures post epilepsy treatment with turmeric

    Time frame: 3 months

07

Study locations

1 site
  • New York University School of Medicine
    New York, New York 10016, United States
08

References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Start is estimated for Mar 2018; primary completion for Nov 2018, 8 months later.

How these figures are worked out, and which studies are left out of them.

Registered
Aug 15, 2017
First posted
Aug 18, 2017
StartEst.
Mar 2018
Primary completionEst.
Nov 2018
CompletionEst.
Nov 2018
Last update
Apr 30, 2018
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Apr 30, 2018, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT03254680
Lead sponsor
NYU Langone Health
Responsible party
Sponsor
First posted
Aug 18, 2017
Start date
Mar 2018 (estimated)
Primary completion
Nov 2018 (estimated)
Completion
Nov 2018 (estimated)
Last update
Apr 30, 2018

Study contacts

Manisha Holmes, MD
principal investigator · NYU Langone Health

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is withdrawn, as verified in Apr 2018. You cannot join it, but the record below documents what was studied.

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Discussion

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Studies of the drugs tested here: Turmeric extract · Curcuma longa

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