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Status unknownNCT03231449FEVRIERUpdated May 25, 2018

A Survey of Hospitalizations in Cardiology Units in Sub-Saharan Africa

An observational study in Acute Coronary Syndrome, Heart Failure and Syncope, sponsored by Cardiologie et Développement. Status unknown at 20 sites in 13 countries. Per ClinicalTrials.gov, last updated 2018-05-25.

Sponsored by Cardiologie et Développement · Observational

The sponsor has not verified this record recently (last verified May 2018), so the status shown — last known as Active, not recruiting — may be out of date.
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
5,000
Sex
All
01

Study summary

FEVRIER study is an observatory of hospitalizations in cardiology units in sub-Saharan Africa.

Read the detailed description

FEVRIER is an observational study based on a questionnaire completed by investigators for each hospitalization in cardiology unit during the month of February.The investigator is a physician of the participating hospital.

FEVRIER evaluates the modalities of care management. It will take place in cardiology units of hospitals of sub-Saharian countries one month per year (month of February) during 5 years.

The investigator will thoroughly complete:

  • one information form describing the hospital and the department
  • one questionnaire (2o questions) for each hospitalized patient

Patients with at least one day of hospitalization will be enrolled in the study. On the first day of February, all patients already hospitalized will be enrolled and all patients hospitalized in the last day of February will be followed until their discharge. thus, data collection will start 1st day of investigation, during February and will continue until the discharge of the last enrolled patient.

02

Conditions studied

  • Acute Coronary Syndrome
  • Heart Failure
  • Syncope
  • Stroke
  • Pericarditis
  • Endocarditis
  • Conduction Abnormalities
  • Rhythm; Abnormal
  • Pulmonary Embolism
  • Deep Vein Thrombosis
  • Other Cardiovascular Conditions

Keywords

  • routine care, evaluation, Africa, observatory
03

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Each patient hospitalized in cardiology unit of participating centers during the month of February can be included.

Inclusion criteria

  • to be hospitalized in a cardiology department of a participating center during the month of February

Exclusion criteria

Exclusion Criteria:

  • refusal
04

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
5,000 participants (estimated)
Patient registry
No

Interventions

  • Otherobservation of current care

    The study FEVRIER (survey of hospitalizations in cardiology units in sub-Saharan Africa) aims to establish a description of sub-Saharan standard of care, in order to get a cross sectional analysis (globally and per country) and a longitudinal analysis (evolution during 5 years).

05

What researchers measure

Primary outcomes

  1. Description of patients in cardiology unit in sub-Saharan Africa:socio-demographic characterization

    low/medium low / medium high/high

    Time frame: 5 years

  2. Description of patients in cardiology unit in sub-Saharan Africa:causes of hospitalization

    one answer with main reason for hospitalization

    Time frame: 5 years

  3. Description of patients in cardiology unit in sub-Saharan Africa: co-morbidities

    cardiovascular risk factors/history of cardiovascular disease/kidney disease/cancer/alcoholism/psychiatric disorder/sickle cell anemia/HIV:Hepatitis/tuberculosis/other

    Time frame: 5 years

  4. Description of patients in cardiology unit in sub-Saharan Africa: hospital examinations

    blood test/ECG/Chest Xray/Echocardiography/Coronarography/Brain scan

    Time frame: 5 years

  5. Description of patients in cardiology unit in sub-Saharan Africa: duration of hospitalization

    number of days spent in cardiology departement

    Time frame: 5 years

  6. Description of patients in cardiology unit in sub-Saharan Africa: discharge diagnosis

    medical conclusion

    Time frame: 5 years

Secondary outcomes

  1. number of patients with heart failure

    to measure the evolution of the number of patients with heart failure over 5 years

    Time frame: 5 years

  2. number of patients with myocardial infarction

    to measure the evolution of the number of patients with myocardial infarction over 5 years

    Time frame: 5 years

  3. number of patients with atrial fibrillation

    to measure the evolution of the number of patients with atrial fibrillation over 5 years

    Time frame: 5 years

06

Study locations

20 sites
  • Centre national hospitalier et universitaire Koutoukou Maga
    Cotonou, Benin
  • Centre médical Paul IV
    Ouagadougou, Burkina Faso
  • Hopital militaire de Kamenge et polyclinique maison médicale
    Bujumbura, Burundi
  • Hôpital Régional
    Bafoussam, Cameroon
  • Douala General Hospital
    Douala, Cameroon
  • Central Hospital
    Yaounde, Cameroon
  • Hôpital Général de Yaoundé
    Yaounde, Cameroon
  • Clinique Ngaliema
    Kinshasa, Congo, The Democratic Republic of the
  • Clinique universitaire de Kinshasa
    Kinshasa, Congo, The Democratic Republic of the
  • CHU
    Brazzaville, Congo
  • Institut de Cariologie d'Abidjan
    Abidjan, Côte D'Ivoire
  • CHU
    Bouake, Côte D'Ivoire
  • Centre Hospitalier Universitaire (CHUL)
    Libreville, Gabon
  • CHU Ignace Deen
    Conakry, Guinea
  • Institut du coeur
    Maputo, Mozambique
  • Hôpital National Lamorde
    Niamey, Niger
  • Hôpital de Fann
    Dakar, Senegal
  • Hôpital général de Grand Yoff
    Dakar, Senegal
  • El Hadj-Ibrahima Niass
    Kaolac, Senegal
  • National Cardiothoracic center / Shab Teaching Hospital
    Khartoum, Sudan
07

References and documents

Publications

  • Marijon E, Ou P, Celermajer DS, Ferreira B, Mocumbi AO, Jani D, Paquet C, Jacob S, Sidi D, Jouven X. Prevalence of rheumatic heart disease detected by echocardiographic screening. N Engl J Med. 2007 Aug 2;357(5):470-6. doi: 10.1056/NEJMoa065085. PubMed 17671255 ↗
  • Marijon E, Celermajer DS, Tafflet M, El-Haou S, Jani DN, Ferreira B, Mocumbi AO, Paquet C, Sidi D, Jouven X. Rheumatic heart disease screening by echocardiography: the inadequacy of World Health Organization criteria for optimizing the diagnosis of subclinical disease. Circulation. 2009 Aug 25;120(8):663-8. doi: 10.1161/CIRCULATIONAHA.109.849190. Epub 2009 Aug 10. PubMed 19667239 ↗
  • Marijon E, Mirabel M, Celermajer DS, Jouven X. Rheumatic heart disease. Lancet. 2012 Mar 10;379(9819):953-964. doi: 10.1016/S0140-6736(11)61171-9. PubMed 22405798 ↗
  • Ranque B, Menet A, Diop IB, Thiam MM, Diallo D, Diop S, Diagne I, Sanogo I, Kingue S, Chelo D, Wamba G, Diarra M, Anzouan JB, N'Guetta R, Diakite CO, Traore Y, Legueun G, Deme-Ly I, Belinga S, Boidy K, Kamara I, Tharaux PL, Jouven X. Early renal damage in patients with sickle cell disease in sub-Saharan Africa: a multinational, prospective, cross-sectional study. Lancet Haematol. 2014 Nov;1(2):e64-73. doi: 10.1016/S2352-3026(14)00007-6. Epub 2014 Oct 28. PubMed 27030156 ↗
  • Marijon E, Ou P, Celermajer DS, Ferreira B, Mocumbi AO, Sidi D, Jouven X. Echocardiographic screening for rheumatic heart disease. Bull World Health Organ. 2008 Feb;86(2):84. doi: 10.2471/blt.07.046680. No abstract available. PubMed 18297157 ↗
  • Yusuf S, Rangarajan S, Teo K, Islam S, Li W, Liu L, Bo J, Lou Q, Lu F, Liu T, Yu L, Zhang S, Mony P, Swaminathan S, Mohan V, Gupta R, Kumar R, Vijayakumar K, Lear S, Anand S, Wielgosz A, Diaz R, Avezum A, Lopez-Jaramillo P, Lanas F, Yusoff K, Ismail N, Iqbal R, Rahman O, Rosengren A, Yusufali A, Kelishadi R, Kruger A, Puoane T, Szuba A, Chifamba J, Oguz A, McQueen M, McKee M, Dagenais G; PURE Investigators. Cardiovascular risk and events in 17 low-, middle-, and high-income countries. N Engl J Med. 2014 Aug 28;371(9):818-27. doi: 10.1056/NEJMoa1311890. PubMed 25162888 ↗

Individual participant data

Plan to share: No

08

Registry details

Key details

Study ID
NCT03231449
Lead sponsor
Cardiologie et Développement
Collaborators
Institut National de la Santé Et de la Recherche Médicale, France
Responsible party
Xavier Jouven (Professor, Cardiologie et Développement) — Principal investigator
First posted
Jul 27, 2017
Start date
Feb 1, 2017
Primary completion
Dec 2020 (estimated)
Completion
Feb 2021 (estimated)
Last update
May 25, 2018

Study contacts

Xavier Jouven, MD, PhD
principal investigator · cardiologie et Developpement

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

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This study is status unknown, as verified in May 2018. You cannot join it, but the record below documents what was studied.

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