An observational study in Appendicitis, sponsored by University of Monastir. Completed at 1 site in Tunisia. Open to participants aged 10 Years and older. Per ClinicalTrials.gov, last updated 2016-09-01.
Sponsored by University of Monastir · Observational
The diagnosis of acute appendicitis is difficult and despite important advances in medical sciences, detailed patient questioning and precise medical examination are the main keystones of the diagnosis of acute appendicitis and up to now, results still unsatisfactory.
Acute appendicitis is the most common surgical emergency and the most common source of community-acquired intra-abdominal infections. The lack of accuracy in the diagnosis of acute appendicitis yields often to two types of outcomes: a delay in diagnosis leads to perforation and peritonitis in up to 15% of the cases and unnecessary appendectomy is associated with post-operative complications such as wound infection and adhesions. CRP is an acute phase protein that is often used by many surgeons as a diagnostic marker of acute appendicitis. During the evaluation of patients with possible appendicitis in the emergency department (ED), repeated physical examination of the abdomen may provide further information about the decision making. However, the role of repeated laboratory examinations is not proven.
The purpose of this study was to investigate whether repeated serum CRP measures could be useful to predict acute appendicitis, after 3 hours of observation, in comparison with the histopathological findings.
412 studies on the registry are indexed under Appendicitis; 62 are open to participants now.
This study's enrollment of 500 is above the median of 200 across 150 observational studies indexed under Appendicitis.
Browse Appendicitis studies →University of Monastir is the lead sponsor of 112 studies on the registry; 30 are open to participants now.
Counted across the registry records on this site, refreshed daily.
All patients presenting to the Fattouma Bourguiba University hospital with an equivocal diagnosis of acute appendicitis. The clinical suspiscion of appendicitis was made based on anamnestic and physical examination findings.
Exclusion Criteria:
all patients admitted to our hospital with a clinically suspected acute appendicitis.
Biological: C-reactive protein measurement
All patients included in this study underwent a blood sample analysis for C-reactive protein concentrations at admission and 3 hours later.
Final diagnosis of acute appendicitis
The final diagnosis of acute appendicitis was based, in operated patients, on the results of the histologic examination of the excised appendix and, in non operated patients, on the absence of acute appendicitis at the 2 weeks follow-up visit.
Time frame: 15 days from patients inclusion
Plan to share: Undecided
This study is completed, as verified in Aug 2016. You cannot join it, but the record below documents what was studied.
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University of Monastir