An interventional study of Cognitive therapy in Stroke, sponsored by University College, London. Completed at 1 site in United Kingdom. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2020-01-29.
Sponsored by University College, London · Not applicable, Interventional, and Treatment
People with global aphasia (PwGA) post stroke have little to no meaningful communication abilities (ie limited comprehension, spoken language, reading and writing abilities).A proportion of PwGA will also have limited abilities to use any alternative means of communication e.g. gesture, pictures or computer devices. There is a suggestion in the literature that this is because of co-occurring cognitive deficits. The consequence is that these clients are unable to reliably communicate even their basic needs.This is commonly known as having no functional communication abilities. Such PwGA tend not to respond to standard speech and language therapy interventions.
This research will investigate the effect of a new cognitive intervention designed to improve basic functional communication abilities. The treatment will be nonverbal and involve computer and paperbased tasks ordered hierarchically from basic to more complex tasks. Six to eight participants will take part. All their sessions will take place in their own home. For some this may be a care home. They will first complete a diagnostic communication assessment in order for baseline abilities to be established. Further formal language and cognitive assessments will be conducted over a period of 6 weeks. A relative/friend will complete a questionnaires about mood/communication. The PwGA will also be videoed interacting with the research student e.g. looking at a magazine, completing a jigsaw, answering questions and making choices non-verbally.
The participants then receive the new intervention 3 times a week for 6 consecutive weeks. All intervention sessions will be videoed. Then participants will be reassessed over 2 weeks using the same assessments as prior to the intervention. The questionnaire with their relative/friend and videoed activity session will also be repeated. After a twelve week break the participant will be videoed interacting with the research student complete some of the assessments again and their relative will re-complete the questionnaires.
365 studies on the registry are indexed under Aphasia; 89 are open to participants now.
This study's enrollment of 6 is below the median of 30 across 316 interventional studies indexed under Aphasia.
Browse Aphasia studies →University College, London is the lead sponsor of 632 studies on the registry; 145 are open to participants now.
Of its 6 completed or terminated interventional studies of FDA-regulated products, 2 (33%) have results posted.
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Exclusion Criteria:
Language and cognitive assessments conducted
Intervention given: visual tracking pressing a button every time a picture is seen on the screen * playing dominoes and snap * pressing a button every time a specific picture is seen on the screen * Pressing a button every time a specific sound is heard * Matching objects to a picture * Matching gestures to objects * Matching two connected objects * Sorting objects by categories * Matching sounds to objects * "Complete the category" and "odd on out with objects" * Choosing target objects by pointing * Choosing objects to complete the category by pointing
Behavioral: Cognitive therapy
Repeated testing
The tasks are: * visually tracking a picture as it moves across the computer screen * pressing a button every time a picture is seen on the screen * pressing a button every time a specific picture is seen on the screen * Pressing a button every time a specific sound is heard * Matching objects to a picture * Matching gestures to objects * Matching two connected objects * Sorting objects by categories * Matching sounds to objects * "Complete the category" and "odd on out with objects" * Choosing target objects by pointing * Choosing objects to complete the category by pointing
American Speech and Hearing Association -Functional Assessment of Communication
Questionnaire completed by friend/relative
Time frame: 27 weeks
Constructed Interaction Task
video recorded interaction
Time frame: 27 weeks
Aphasia Screening Test
Language assessment
Time frame: 14 weeks
Mood Screen
depression screening tool
Time frame: 27 weeks
Pyramids and Palm Trees Test
pictorial semantic assessment
Time frame: 27 weeks
Wisconsin Card Sorting Test
cognitive assessment
Time frame: 14 weeks
Butt Non verbal reasoning test
cognitive assessment
Time frame: 27 weeks
Western Aphasia Battery cognitive sub test
cognitive assessment
Time frame: 14 weeks
Plan to share: No
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This study is completed, as verified in Jan 2020. You cannot join it, but the record below documents what was studied.
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University College, London