An interventional study of HDT and ACDT in Major Depressive Disorder, sponsored by University Hospital Tuebingen. Completed at 1 site in Germany. Open to participants aged 18 Years to 70 Years. Per ClinicalTrials.gov, last updated 2018-09-25.
Sponsored by University Hospital Tuebingen · Not applicable, Interventional, and Treatment
The purpose of the study is to compare the efficacy of an Hypnotherapeutic Treatment of Depression to Cognitive Behavioral Treatment of Depression in patients with mild to moderate Major Depressive Episodes.
Cognitive Behavioral Therapy (CBT) is considered to be an effective psychological treatment of mild to moderate Major Depressive Episodes. Effective treatments, however, show a reduction of depressive symptoms only up to 50 % (Luty et al., 2007) which is one reason for the modification of the well-established CBT in the last years. Following the 'third wave' approaches of CBT, e.g. Emotion-Focussed Therapy or Mindfulness-Based Cognitive Therapy, techniques like meditation or the use of systemic or Gestalt techniques within CBT has been applied. Within this context, Hypnotherapy-based strategies can also show an improvement of the current state of the art in depression psychotherapy. However, only few studies conducted randomised controlled trials to study the efficacy of hypnosis for depression as e.g. the comparison of cognitive hypnotherapy to CBT-alone (e.g. Alladin and Alibhai, 2007). With the present study, the efficacy of the Hypnotherapeutic Treatment of Depression (HDT) will be compared to the CBT-based Activation-focussed Cognitive Treatment of Depression (ACDT). Both treatments are individually administered and includes 20 sessions. We expect HDT not being inferior to ACDT in the reduction of depressive symptoms after six months of treatment.
8,057 studies on the registry are indexed under Depression; 1,643 are open to participants now.
This study's enrollment of 153 is above the median of 84 across 6,718 interventional studies indexed under Depression.
Browse Depression studies →University Hospital Tuebingen is the lead sponsor of 476 studies on the registry; 104 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
HDT (Hypnotherapeutic Treatment of Depression) focuses on the hypnotic activation and strengthening of individual resources, the use of regression techniques to rebuild positive and negative experiences and the development of positive imaginations for the future.
Behavioral: HDT
ACDT (Activation-focussed Cognitive Treatment of Depression) focuses on psychoeducation, behavior activation, the use of cognitive techniques, and the improvement of social skills.
Behavioral: ACDT
20 sessions, individual psychotherapy
Also known as: Hypnotherapeutic Treatment of Depression
20 sessions, individual psychotherapy
Also known as: Cognitive Behavioral Therapy (CBT) of Depression
Montgomery-Åsberg Depression Rating Scale (MADRS)
Clinician-rating of depressive symptoms, Primary outcome
Time frame: Change from Baseline in MADRS to end of treatment (20 sessions in 20-24 weeks)
QIDS: Quick Inventory of Depressive Symptomatology - Clinician Rating (QIDS-C16)
Clinician-rating of depressive symptoms
Time frame: Change from Baseline to end of therapy and follow-ups (six and 12 months after end of treatment)
Patient Health Questionnaire (PHQ-9)
Self-report of depressive symptoms
Time frame: Change from Baseline to end of therapy and follow-ups (six and 12 months after end of treatment)
Montgomery-Åsberg Depression Rating Scale (MADRS)
Incidence of response rate (symptom reduction \> 60%)
Time frame: six and 12 months after end of treatment
This study is completed, as verified in Sep 2018. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
University Hospital Tuebingen