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CompletedNCT02126150UNICORNUpdated Dec 8, 2015

United Coronary Biobanks

An observational study in Coronary Artery Disease, Acute Coronary Syndrome and Myocardial Infarction, sponsored by UMC Utrecht. Completed at 1 site in Singapore. Open to participants aged 21 Years and older. Per ClinicalTrials.gov, last updated 2015-12-08.

Sponsored by UMC Utrecht · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
2,000
Ages
21 Years and older
Sex
All
01

Study summary

The UNICORN consists of two collaborating biobanks, one in Utrecht and one in Singapore. From these two sites we include all patients who undergo a coronary catheterization for any reason.

At the moment of catheterization we draw blood, which will be stored in a biobank and we collect clinical characteristics. Patients are followed-up for 5 years for the occurrence of major cardiovascular events.

By including from two sites in the world we include 4 major ethnic groups: Caucasians, Chinese, Indians and Malays. We aim at including at least 2000 patients per ethnic group.

Our hypothesis is that there are differences in the risk factor burden, clinical presentation of CAD, and biochemical patterns in the blood among the ethnic groups.

Furthermore, this biobank offers a platform for multi-ethnic biomarker discovery.

02

Conditions studied

  • Coronary Artery Disease
  • Acute Coronary Syndrome
  • Myocardial Infarction
  • Stable Angina
03

In context

Coronary Artery Disease

5,598 studies on the registry are indexed under Coronary Artery Disease; 955 are open to participants now.

This study's enrollment of 2,000 is above the median of 336 across 1,946 observational studies indexed under Coronary Artery Disease.

Browse Coronary Artery Disease studies →

Lead sponsor

UMC Utrecht is the lead sponsor of 350 studies on the registry; 80 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
21 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

All patients that undergo coronary catheterization for any reason are eligible to enroll in the study.

Inclusion criteria

  • Patients undergoing coronary angiography

Exclusion criteria

Exclusion Criteria:

  • \< 21 years of age
  • Hemoglobin levels \<7 g/dL in women, or hemoglobin levels \<8 g/dL in men
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
2,000 participants (actual)
Patient registry
No
Biospecimen retention
Samples with dna

Groups and cohorts

  • Ethnicity
06

What researchers measure

Primary outcomes

  1. All-cause death

    Time frame: 5 years

Secondary outcomes

  1. Major cardiovascular events

    Time frame: 5 years

07

Study locations

1 site
  • National University Hospital
    Singapore, 119074, Singapore
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 8, 2015, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT02126150
Lead sponsor
UMC Utrecht
Collaborators
National University Hospital, Singapore
Responsible party
Crystel Gijsberts (MD, UMC Utrecht) — Principal investigator
First posted
Apr 29, 2014
Start date
Sep 2010
Primary completion
Dec 2015
Completion
Dec 2015
Last update
Dec 8, 2015

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Dec 2015. You cannot join it, but the record below documents what was studied.

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