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Status unknownNCT02068261Updated Oct 23, 2015

Working Memory Training in Adults With Substance Abuse and Executive Function Deficits.

A Phase 2 interventional study of Computerized Cogmed working memory training and Treatment as usual in Substance Abuse, Executive Dysfunction and Anxiety, sponsored by Örebro Läns Landsting. Status unknown at 1 site in Sweden. Open to participants aged 18 Years to 70 Years. Per ClinicalTrials.gov, last updated 2015-10-23.

Sponsored by Örebro Läns Landsting · Phase 2, Interventional, and Treatment

The sponsor has not verified this record recently (last verified Oct 2015), so the status shown — last known as Recruiting — may be out of date.
Phase
Phase 2
Study type
Interventional
Enrollment
100
Allocation
Randomized
Ages
18 Years to 70 Years
Sex
All
01

Study summary

The purpose of this study is to evaluate the effects of a computerized working memory training program on substance abuse, psychosocial functioning, cognitive performance and psychiatric problems in adults with substance abuse and attention problems.

Read the detailed description

The primary aim of this study is to examine the effects of 5 weeks of computerized working memory training on substance abuse. Secondary aims are to explore whether effects are mediated by changes in executive functions and/or moderated by personality. Also, effects on measures of psychosocial functioning, depression, anxiety and attention will be explored. Follow-up assessment will be conducted at 6 months post training.

02

Conditions studied

  • Substance Abuse
  • Executive Dysfunction
  • Anxiety
  • Depression
  • Antisocial Personality
  • Reading Disabilities
03

In context

Dyslexia

124 studies on the registry are indexed under Dyslexia; 27 are open to participants now.

This study's planned enrollment of 100 is above the median of 76 across 106 interventional studies indexed under Dyslexia.

Browse Dyslexia studies →

Lead sponsor

Örebro Läns Landsting is the lead sponsor of 2 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 70 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Treatment seeking adults with substance abuse and executive function deficits.

Exclusion criteria

Exclusion Criteria:

  • Acute intoxication or abstinence symptoms of any substance.
  • Psychosis.
05

Study design

Phase
Phase 2
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
100 participants (estimated)

Study arms

  • Experimental
    Cogmed working memory training

    30-40 minutes of Cogmed computerized working memory training 3-5 days a week for 5-8 weeks. Every training session consists of a set of visual- and verbal working memory tasks that are trained on during the session.

    Behavioral: Computerized Cogmed working memory training

  • Active comparator
    Treatment as usual

    Treatment as usual can consist of medication, psychotherapy, counseling, and psychological assessment. After a 8 week period participants in this arm well be offered Cogmed working memory training.

    Behavioral: Treatment as usual

Interventions

  • BehavioralComputerized Cogmed working memory training

    Computerized working memory training with Cogmed QM software. The QM software consists of a set of verbal and visual working memory tasks which is trained for 25-40 minutes each session.

  • BehavioralTreatment as usual

    Treatment as usual can consist of medication, psychotherapy, counseling, and psychological assessment.

06

What researchers measure

Primary outcomes

  1. Change from baseline in substance abuse measured with Substance abuse scales in Adult Self Report (ASR; ASEBA).

    Time frame: Baseline and at 25 weeks

Secondary outcomes

  1. Change from baseline in Adult Self Report (ASR; ASEBA) Attention problems scale.

    Time frame: Baseline and at 25 weeks

  2. Change from baseline in Adult Self Report (ASR; ASEBA) Internalizing index.

    Time frame: Baseline and at 25 weeks

  3. Change from baseline in Adult Self Report (ASR; ASEBA) Externalizing index.

    Time frame: Baseline and at 25 weeks

  4. Change from baseline in Adult Self Report (ASR; ASEBA) Adaptive functioning scales.

    Time frame: Baseline and at 25 weeks

  5. Change from baseline in Executive functioning measured with Behavior Rating Inventory of Executive Function-Adult (BRIEF-A).

    Time frame: Baseline and at 25 weeks

  6. Change from baseline in verbal working memory measured with performance on Digit span.

    Time frame: Baseline and at 25 weeks

  7. Change from baseline in visual working memory measured with performance on Span board.

    Time frame: Baseline and at 25 weeks

  8. Change from baseline in focused attention measured with performance on Conners Continuous Performance Test-II (CCPT-II).

    Time frame: Baseline and at 25 weeks

  9. Change from baseline in vigilance measured with performance on Conners Continuous Performance Test-II (CCPT-II).

    Time frame: Baseline and at 25 weeks

  10. Change from baseline in reading speed measured with performance on Reading speed in Diagnostic Reading and Writing Test (DLS; Swedish version).

    Time frame: Baseline and at 25 weeks

07

Study locations

1 of 1 sites recruiting
  • Psychiatric Research Centre
    Örebro, 701 16, Sweden
    Recruiting
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Oct 23, 2015, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT02068261
Lead sponsor
Örebro Läns Landsting
Responsible party
Rickard Ahlberg (Clinical psychologist, doctoral student., Örebro Läns Landsting) — Principal investigator
First posted
Feb 21, 2014
Start date
Jan 2014
Primary completion
Dec 2016 (estimated)
Completion
Dec 2016 (estimated)
Last update
Oct 23, 2015

Study contacts

Rickard Ahlberg, doctoral student
Contact
rickard.ahlberg@orebroll.se
Kurt Skårberg, MD
Contact
kurt.skarberg@orebroll.se
Lars Kjellin, Docent
study director · Örebro Läns Landsting

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Oct 2015. You cannot join it, but the record below documents what was studied.

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