A Phase 2 interventional study of OxIGen and OxIGen: control version in Depression, sponsored by University of Oxford. Completed at 2 sites in United Kingdom. Open to participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2014-01-09.
Sponsored by University of Oxford · Phase 2, Interventional, and Treatment
This research study is designed to investigate the effects of an online computer program, called OxIGen (Oxford Imagery Generation), on thinking style and mood in depression. The OxIGen program will be delivered online over four weeks and with follow-up at one, three and six months. This will inform potential future development of this computerized task into an online intervention to modify negative thinking styles in depression.
8,057 studies on the registry are indexed under Depression; 1,641 are open to participants now.
This study's enrollment of 150 is above the median of 84 across 6,720 interventional studies indexed under Depression.
Browse Depression studies →University of Oxford is the lead sponsor of 794 studies on the registry; 117 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Internet based intervention taking place over 4 weeks
Other: OxIGen
A control version of the internet-based OxIGen intervention
Other: OxIGen: control version
Internet-based intervention with 12 sessions over 4 weeks
A control version of the OxIGen internet-based intervention (i.e. identical but with putative active components removed)
Change in score on Beck Depression Inventory - II
Time frame: Baseline and post-intervention (4 weeks)
Change in score on Quick Inventory of Depressive Symptoms - Self Report
Time frame: Baseline and post-intervention (4 weeks)
Change in State-Trait Anxiety Inventory (Trait scale)
Time frame: Baseline and Post-Intervention (4 weeks)
Change on Beck Anxiety Inventory
Time frame: Baseline and Post-Intervention (4 weeks)
Change on Scrambled Sentences Task
Time frame: Baseline and Post-Intervention (4 weeks)
Change on Life Orientation Test - Revised
Time frame: Baseline and Post-Intervention (4 weeks)
Change on Prospective Imagery Test
Time frame: Baseline and Post-Intervention (4 weeks)
Change on Behavioural Activation in Depression Scale
Time frame: Baseline and Post-Intervention (4 weeks)
Change in IAPT Toolkit
Includes the GAD-7, PHQ-9 and Work and Social Adjustment Scale
Time frame: Baseline and Post-Intervention (4 weeks)
Change on EuroQol-5D
Time frame: Baseline and Post-Intervention (4 weeks)
Change in Neuroticism
Time frame: Baseline and Post-Intervention (4 weeks)
Change on Beck Depression Inventory - II
Time frame: Baseline and Follow-Up (one month, three months, six months)
Change on Quick Inventory of Depressive Symptoms - Self Report
Time frame: Baseline and Follow-Up (one month, three months, six months)
Change on State-Trait Anxiety Inventory (Trait scale)
Time frame: Baseline and Follow-Up (one month, three months, six months)
Change on Beck Anxiety Inventory
Time frame: Baseline and Follow-Up (one month, three months, six months)
Change on Life Orientation Test - Revised
Time frame: Baseline and Follow-Up (one month, three months, six months)
Change on Prospective Imagery Test
Time frame: Baseline and Follow-Up (one month, three months, six months)
Change on Behavioural Activation in Depression Scale
Time frame: Baseline and Follow-Up (one month, three months, six months)
Change on IAPT Toolkit
Includes GAD-7, PHQ-9, Work and Social Adjustment Scale
Time frame: Baseline and Follow-Up (one month, three months, six months)
Change on Euroqol-5D
Time frame: Baseline and Follow-Up (one month, three months, six months)
Change on Neuroticism
Time frame: Baseline and Follow-Up (one month, three months, six months)
Image Generation Task
Task adapted from Sharot et al. (2007, Nature)
Time frame: Post-Intervention (4 weeks)
This study is completed, as verified in Jun 2013. You cannot join it, but the record below documents what was studied.
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University of Oxford