An observational study in Complication of Surgical Procedure, Acute Respiratory Failure, Adult and Postoperative Respiratory Complications, sponsored by European Society of Anaesthesiology. Completed at 63 sites in 21 countries. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2022-04-05.
Sponsored by European Society of Anaesthesiology · Observational
Prospective Evaluation of a RIsk Score for postoperative pulmonary COmPlications in Europe (PERISCOPE) is a multi-centre, international observational study of a random-sample cohort of patients undergoing a nonobstetric in-hospital surgical procedure under general or regional anaesthesia during a continued 7-day period of recruitment.
Prospective Evaluation of a RIsk Score for postoperative pulmonary COmPlications in Europe (PERISCOPE) is a multi-centre, international observational study of a random-sample cohort of patients undergoing a nonobstetric in-hospital surgical procedure under general or regional anaesthesia during a continued 7-day period of recruitment.
Participating centres throughout Europe will contribute routine clinical data describing all eligible patients who undergo surgery during a continuous week (7-days) at convenience of every department within a period of two months from May 1st to July 1st 2011. A questionnaire of around 50 items will be filled during the pre, intra and postoperative periods. The follow-up will end at discharge. The aim of the PERISCOPE study is to validate a simple score to predict postoperative pulmonary complications(PPCs). This score has recently been published in Anesthesiology and you can access linking to: http://journals.lww.com/anesthesiology/Fulltext/2010/12000/Prediction_of_Postoperative_Pulmonary.20.aspx
TIMEFRAME Participants will be followed for the duration of in-hospital stay, an expected average of maximum 5 weeks.
1,369 studies on the registry are indexed under Respiratory Insufficiency; 264 are open to participants now.
This study's enrollment of 5,450 is above the median of 100 across 455 observational studies indexed under Respiratory Insufficiency.
Browse Respiratory Insufficiency studies →European Society of Anaesthesiology is the lead sponsor of 17 studies on the registry; 5 are open to participants now.
Counted across the registry records on this site, refreshed daily.
In-patient adult non-obstetric surgery
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Patients undergoing a non-obstetric in-hospital surgical procedure, elective or emergent, under general anaesthesia (alone or in combination with regional/neuraxial anaesthesia), neuraxial anaesthesia or plexus block (with and without sedation).
Exclusion Criteria:
Consecutive patients admitted to participating centres undergoing surgery Non-obstetric in-hospital surgical procedure, elective or emergent, under general anaesthesia (alone or in combination with regional/neuraxial anaesthesia), neuraxial anaesthesia or plexus block (with and without sedation). All eligible patients undergoing surgery within the seven day study period will be recruited wherever possible.
The Main Outcome, Defined as a Postoperative Pulmonary Complications (PPC), Will be a Composite of the In-hospital Fatal or Non-fatal Postoperative Events.
Will include:Mild respiratory failure;Severe respiratory failure;acute lung injury(ALI)/Acute respiratory distress syndrome(ARDS);Suspected pulmonary infection;Pulmonary infiltrate;Pleural effusion;Atelectasis;Pneumothorax;Bronchospasm;Aspiration Pneumonitis;Cardiopulmonary edema.Investigators will not modify centre usual patient management. Patients with PPCs will identify by consulting medical records and looking for events fulfilling PPCdefinition. Diagnosis date for every complication will be recorded.Participants will be followed during in-hospital stay up to 5 weeks.
Time frame: Postoperative in-hospital stay up to 5 weeks
a) Postoperative Length of Stay
Participants will be followed for the duration of in-hospital stay up to 90 days
Time frame: Postoperative in-hospital stay up to 90 days
b) In-hospital Mortality
Participants will be followed for the duration of in-hospital stay up to 90 days
Time frame: Postoperative in-hospital stay up to 90 days
1 week chosen by each centre First Sub First Visit 4-Apr-11 Last data entered 25 Oct 2011
| Milestone | In-patient Adult Non-obstetricSurgical |
|---|---|
| Started | 5450 |
| Completed | 5099 |
| Not completed | 351 |
| Withdrew: Protocol violation | 35 |
| Withdrew: Lost to follow-up | 31 |
| Withdrew: Missing data in candidate risk factor | 285 |
Will include:Mild respiratory failure;Severe respiratory failure;acute lung injury(ALI)/Acute respiratory distress syndrome(ARDS);Suspected pulmonary infection;Pulmonary infiltrate;Pleural effusion;Atelectasis;Pneumothorax;Bronchospasm;Aspiration Pneumonitis;Cardiopulmonary edema.Investigators will not modify centre usual patient management. Patients with PPCs will identify by consulting medical records and looking for events fulfilling PPCdefinition. Diagnosis date for every complication will be recorded.Participants will be followed during in-hospital stay up to 5 weeks.
| Percentage of Participants | In-patient Adult Non-obstetricSurgical |
|---|---|
| The Main Outcome, Defined as a Postoperative Pulmonary Complications (PPC), Will be a Composite of the In-hospital Fatal or Non-fatal Postoperative Events. | 7.92 (7.20 to 8.70) |
Participants will be followed for the duration of in-hospital stay up to 90 days
| days | In-patient Adult Non-obstetricSurgical |
|---|---|
| a) Postoperative Length of Stay | 4 (2 to 7) |
Participants will be followed for the duration of in-hospital stay up to 90 days
| percentage of Participants | In-patient Adult Non-obstetricSurgical |
|---|---|
| b) In-hospital Mortality | 0.9 |
Non-serious events are listed at a 0% frequency threshold.
| Group | Deaths | Serious | Other |
|---|---|---|---|
| Observational Study Section Not Applicable | — | — | — |
| Age, Customized(participants) | In-patient Adult Non-obstetricSurgical |
|---|---|
| <=50years | 1763 |
| 51-80years | 2944 |
| >80years | 392 |
| Age, Customized(years) | In-patient Adult Non-obstetricSurgical |
|---|---|
| Age Median | 59.1 (44.9 to 70.9) |
| Sex: Female, Male(Participants) | In-patient Adult Non-obstetricSurgical |
|---|---|
| Female | 2493 |
| Male | 2606 |
| Body Mass Index(kg/m^2) | In-patient Adult Non-obstetricSurgical |
|---|---|
| Median | 26.2 (23.4 to 29.4) |
| Smoking status(participants) | In-patient Adult Non-obstetricSurgical |
|---|---|
| Never Smoker | 2674 |
| Former Smoker | 1245 |
| Current Smoker | 1180 |
| Chronic obstructive pulmonary disease (COPD)(participants) | In-patient Adult Non-obstetricSurgical |
|---|---|
| COPD = yes | 517 |
| COPD = no | 4582 |
| Functional Status(participants) | In-patient Adult Non-obstetricSurgical |
|---|---|
| Independant | 4561 |
| Partally/totally dependant | 538 |
| Hypertension(participants) | In-patient Adult Non-obstetricSurgical |
|---|---|
| Hypertension = yes | 2191 |
| Hypertension = no | 2908 |
15 further baseline measures are reported on the registry.
The record gives a start of May 2011, a primary completion of Aug 2011 and a completion of Sep 2011. It does not say whether these dates are actual or estimated.
Results were first posted in Apr 2022, 10 years 8 months after primary completion.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Oct 2015. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
European Society of Anaesthesiology