An observational study in Cerebral Ischemia, sponsored by European Society of Anaesthesiology. Recruiting at 1 site in Germany. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2024-04-17.
Sponsored by European Society of Anaesthesiology · Observational
Endovascular thrombectomy is the standard of care for acute ischaemic stroke due to large-vessel occlusion. Current guidelines for periprocedural anaesthesiological care give gross recommendations on management of stroke patients during recanalization, but lack detailed information.
To determine how anaesthesiologists support endovascular thrombectomy with regard to anaesthetic technique, choice of substances, haemodynamic management, and ventilation. With a multivariate analysis, the investigators will look for the factors of anesthetic management that are independently correlated with a good or bad outcome.
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217 studies on the registry are indexed under Brain Ischemia; 42 are open to participants now.
This study's planned enrollment of 2,500 is above the median of 203 across 72 observational studies indexed under Brain Ischemia.
Browse Brain Ischemia studies →European Society of Anaesthesiology is the lead sponsor of 17 studies on the registry; 5 are open to participants now.
Counted across the registry records on this site, refreshed daily.
The target population consists of patients undergoing emergency endovascular thrombectomy for treatment of AIS-LVO. The planned minimum sample size is 5,000 patients.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
there is only one group of the subjects that had stroke and went under thrombectomy procedure and to see how anaesthesiologists support endovascular thrombectomy with regard to anaesthetic technique,choice of substances, haemodynamic management, and ventilation.
Neurological outcome 90 days after the stroke
Neurological outcome is measured using the modified Rankin Scale \[0-6\], with higher values indicating worse outcome. As a Primary Outcome Measure, the scale will be dichotomized into good (modified Rankin Scale ≤ 2) versus poor (modified Rankin Scale \> 2) outcome.
Time frame: 90 days
Mortality
Mortality rate 90 days after the stroke. Mortality rate is the percentage of patients that have died within 90 days following their stroke.
Time frame: 90 days
Grade of recanalization
Recanalization is classified according to the modified Thrombolysis in Cerebral Infarction classification (mTICI) \[0 - 3\], with higher values indicating better reperfusion.
Time frame: sixty minutes
Duration
Duration \[minutes\] from patient's arrival in angiography suite to arterial puncture for endovascular thrombectomy. Duration \[minutes\] from patient's arrival in angiography suite to arterial puncture for endovascular thrombectomy. Duration \[minutes\] from arterial puncture to end of endovascular thrombectomy.
Time frame: 30 Minutes
Proportion of patients breathing spontaneously
Proportion of patients breathing spontaneously after thrombectomy \[Time Frame: On transfer from angiography suite after thrombectomy, which typically takes 1 hour\]. This is defined as percentage of patients that breathe spontaneously without laryngeal mask, laryngeal tube, or endotracheal tube after thrombectomy.
Time frame: sixty minutes
Plan to share: No
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Started Aug 2021 (actual). Primary completion is estimated for Apr 2024, 32 months after the start.
Of 34 non-industry observational studies under Brain Ischemia, half reached primary completion within 72 months of starting (the median), counting those still running; a quarter within 36 and three quarters within 121. This study's planned 32 months is below that.
Counting every sponsor, half of 36 studies reached it within 72 months; a quarter within 36 and three quarters within 121.
How these figures are worked out, and which studies are left out of them.
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European Society of Anaesthesiology