An observational study in Chronic Heart Failure, Coronary Disease and Dilated Cardiomyopathy, sponsored by National Taiwan University Hospital. Status unknown at 1 site in Taiwan. Open to male participants aged 40 Years to 75 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2010-06-08.
Sponsored by National Taiwan University Hospital · Observational
Shortness of breath, fatigue, and exercise intolerance are clinical symptoms of chronic heart failure (CHF). Recent studies suggested that peripheral impairment was the major cause of clinical symptoms, and mechanism may be related to neuroendocrine impairment and vascular smooth muscle dysfunction. It results in increased peripheral resistance that may influence limb blood flow, muscle fitness and activities of daily.The purposes of this study are
5,701 studies on the registry are indexed under Heart Failure; 1,220 are open to participants now.
This study's planned enrollment of 100 is below the median of 200 across 1,679 observational studies indexed under Heart Failure.
Browse Heart Failure studies →National Taiwan University Hospital is the lead sponsor of 2,563 studies on the registry; 569 are open to participants now.
Of its 11 completed or terminated interventional studies of FDA-regulated products, 2 (18%) have results posted.
Counted across the registry records on this site, refreshed daily.
Chronic Heart Failure Coronary Disease Dilated Cardiomyopathy Control group without diagnosis of any heart disease
Exclusion Criteria:
Diagnosis of cardiomyopathy or ischemic heart disease without heart failure
Diagnosis of cardiomyopathy or ischemic heart disease LVEF \<40%
Age and body built matched with chronic heart failure group
muscle strength and endurance
Measured by biodex
Time frame: baseline
skeletal muscle oxygenation response
Measured by near-infrared spectroscopy
Time frame: baseline
Walking distance in 6-minute walking test
walking distance (m)
Time frame: baseline
laser Doppler flowmetry combine iontophoresis
To measure the blood flux (PU) response to Ach (endothelial-dependent agent) and SNP (endothelial-independent agent)
Time frame: baseline
sit-to-stand test
Measured times in 1 minute
Time frame: baseline
questionnaire (functional activity and quality of life)
Time frame: baseline
Analysis of venous blood sample
By standard venipuncture
Time frame: baseline
This study is status unknown, as verified in Jun 2010. You cannot join it, but the record below documents what was studied.
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National Taiwan University Hospital