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CompletedNCT01103557Updated Apr 14, 2010

Prophylactic Selective Lateral Neck Dissection in Patients With Papillary Thyroid Carcinoma

An interventional study of prophylactic selective lateral neck dissection in Thyroid Neoplasm and Lymphatic Metastasis, sponsored by Pusan National University Hospital. Completed. Open to participants aged 20 Years to 76 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2010-04-14.

Sponsored by Pusan National University Hospital · Not applicable, Interventional, and Diagnostic

Phase
Not applicable
Study type
Interventional
Enrollment
62
Allocation
Not applicable
Ages
20 Years to 76 Years
Sex
All
01

Study summary

The purpose of this study is to prospectively analyze the incidence of occult lateral neck metastasis (LNM) and to elucidate the factors that predict LNM in papillary thyroid carcinoma (PTC) with central neck metastasis (CNM) by performing prophylactic selective lateral neck dissection (SND).

Read the detailed description

The lymphatic drainage pattern of the thyroid is uniform and consistent, and therefore, metastatic patterns are relatively predictable. Initial nodal metastasis in PTC usually occurs in the paratracheal and pretracheal nodes in level VI of the central compartment of the ipsilateral neck and spreads to the lateral cervical lymph nodes. Macroscopic skip metastases to the lateral compartment of the neck in the absence of central disease are uncommon.

02

Conditions studied

  • Thyroid Neoplasm
  • Lymphatic Metastasis

Keywords

  • Papillary thyroid carcinoma with neck metastasis
  • neck dissection
03

In context

Carcinoma

6,741 studies on the registry are indexed under Carcinoma; 1,161 are open to participants now.

This study's enrollment of 62 is above the median of 45 across 5,170 interventional studies indexed under Carcinoma.

Browse Carcinoma studies →

Lead sponsor

Pusan National University Hospital is the lead sponsor of 78 studies on the registry; 8 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years to 76 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Papillary thyroid carcinoma with central neck metastasis
  • No evidence of lateral neck metastasis as determined by high-resolution neck ultrasonography and computed tomography

Exclusion criteria

Exclusion Criteria:

  • History of previous thyroid operation
  • Isthmic thyroid lesion
05

Study design

Phase
Not applicable
Primary purpose
Diagnostic
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
62 participants (actual)

Interventions

  • Procedureprophylactic selective lateral neck dissection

    Level II, III, IV lymph node dissection

06

Study locations

No study locations are listed for this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 14, 2010, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT01103557
Lead sponsor
Pusan National University Hospital
First posted
Apr 14, 2010
Last update
Apr 14, 2010

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jan 2010. You cannot join it, but the record below documents what was studied.

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