Lymphatic Metastasis clinical trials
The registry lists 213 studies for Lymphatic Metastasis across more than 10 countries. 77 are recruiting or about to start. 48 of them are mainly about Lymphatic Metastasis (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06.
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Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Status
Who runs them
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University (8) · Cancer Institute and Hospital, Chinese Academy of Medical Sciences (6) · Fudan University (6) · Radboud University Medical Center (6) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (4) · Maastricht University Medical Center (4) · IRCCS San Raffaele (3) · Odense University Hospital (3)
What is being tested here
Drugs under test in Lymphatic Metastasis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Cisplatin | 3 | 1 | 3 |
| Indocyanine Green | 1 | 1 | 3 |
| Propranolol | 1 | 0 | 1 |
| Tislelizumab | 1 | 0 | 1 |
| Gemcitabine | 1 | 0 | 1 |
| Iparomlimab | 1 | 0 | 1 |
| Tuvonralimab | 1 | 0 | 1 |
| Paclitaxel | 1 | 1 | 1 |
| Cabozantinib | 0 | 1 | 1 |
| QL2107 | 0 | 1 | 1 |
Drug classes tested here Immune checkpoint inhibitors 2 open · Tyrosine kinase inhibitors (TKIs) 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026Pharmacokinetic Study of QL2107 Versus Keytruda® for Adjuvant Therapy of Non-Small Cell Lung Cancer (NSCLC) · Phase 3 · Qilu Pharmaceutical Co., Ltd.
- Nov 2026Axillary LNs Evalution in Breast Cancer by Multimodal Us · Assiut University
- Dec 2026Risk of Esophageal Cancer Returning After Immunotherapy, Chemotherapy, and Surgery · Peking University Cancer Hospital & Institute
- Dec 2026Lymph Node Dissection After Neoadjuvant Therapy for Gastric and EGJ Adenocarcinoma · The First Affiliated Hospital with Nanjing Medical University
- Dec 2026NODE (groiN ultrasOunD cancEr) · Queensland Centre for Gynaecological Cancer
- Jan 2027Maximizing Lymph Node Dissection on Fresh and Fixed Lung Cancer Resection Specimens · Brigham and Women's Hospital
- Jan 2027MMR Status Modulates the Predictive Value of Lymphatic Invasion for Lymph Node Metastasis in Gastrointestinal Cancers · Shanghai Zhongshan Hospital
- Feb 2027Advanced Radiotherapy (ART) in Prostate Cancer (PROST-ART) · IRCCS San Raffaele
- Apr 2027XR-Assisted PET/CT Navigation for Cervical Lymph Node Dissection in Lung Cancer · National Taiwan University Hospital
- Apr 2027Real-World Study on Efficacy and Influencing Factors of Immunotherapy for Pan-Cancer Lymph Node Metastases. · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Who these studies take
Of the 48 Lymphatic Metastasis studies recruiting now, 26 (54%) set no upper age limit and 8 (17%) stop at 75 or younger. 5 (10%) take children under 18. 13 (27%) are for women only and 2 (4%) for men only; 2 (4%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 5 (10%) | 5 (10%) |
| 18 | 42 (88%) | 32 (67%) |
| 30 | 45 (94%) | 35 (73%) |
| 40 | 45 (94%) | 35 (73%) |
| 50 | 46 (96%) | 35 (73%) |
| 65 | 46 (96%) | 35 (73%) |
| 75 | 44 (92%) | 34 (71%) |
| 85 | 33 (69%) | 26 (54%) |
Across all 213 studies, recruiting or not: 17% stop at 75 or younger and 2% at 65; 15% take children; 20% are for women only and 8% for men only; 4% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Lymphatic Metastasis studies take
Of 50 interventional studies with no phase under Lymphatic Metastasis, half reached primary completion within 64 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 64 mo35–98 · 50 studies | — | — |
| Observational | 40 mo24–79 · 42 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Stopped1
- Device Validation of Augmented-Reality ICG Fluorescence Imaging for Sentinel Lymph Node Detection in Breast CancerWithdrawnNov 5, 2026NCT07683572
Newly registered4
- Station-Specific Lymph Node Metastasis After Neoadjuvant Chemoimmunotherapy for Middle Thoracic Esophageal Squamous Cell CarcinomaOct 29, 2026NCT07902544
- Lymph Node Dissection After Neoadjuvant Therapy for Gastric and EGJ AdenocarcinomaOct 29, 2026NCT07902596
- T1 Colorectal Cancer After Local Excision: Decision Between Surgery and Active Surveillance (T1LDA Trial)Oct 28, 2026NCT07900620
- Phase II Study of Primary Tumor Resection and Selective Lymph Node Dissection Followed by RT for BTC With Lymph Node MetastasesOct 26, 2026NCT07893392
Studies
Recruiting first, then most recently updated. Showing 50 of 213. Browse all 213 → or search them.
- Augmented-Reality ICG Fluorescence Second-Look for Residual Nodal Disease After Axillary Dissection in Breast CancerNot yet recruitingNCT07696754Not applicable1 country
- Lymph Node Dissection After Neoadjuvant Therapy for Gastric and EGJ AdenocarcinomaNot yet recruitingNCT079025961 country
- T1 Colorectal Cancer After Local Excision: Decision Between Surgery and Active Surveillance (T1LDA Trial)Not yet recruitingNCT07900620Not applicable1 country
- Advanced Radiotherapy (ART) in Prostate Cancer (PROST-ART)RecruitingNCT065462671 country
- MMR Status Modulates the Predictive Value of Lymphatic Invasion for Lymph Node Metastasis in Gastrointestinal CancersNot yet recruitingNCT07625735
- Phase II Study of Primary Tumor Resection and Selective Lymph Node Dissection Followed by RT for BTC With Lymph Node MetastasesRecruitingNCT07893392Phase 21 country
- Stromal Desmoplastic Reaction as a Predictive Factor for Lymph Node Metastasis in Medullary Thyroid CancerNot yet recruitingNCT07851324
- Urologic Lymphadenectomy in AMIGORecruitingNCT05132283Not applicable1 country
- Neck Observation or Elective Neck Dissection in cT1N0M0 OSCCRecruitingNCT06623266Not applicable1 country
- Risk of Esophageal Cancer Returning After Immunotherapy, Chemotherapy, and SurgeryNot yet recruitingNCT078229061 country
- Molecular Residual Disease Assessment in a Representative Diverse Population of Patients With Early-stage Breast CancerRecruitingNCT07025785Not applicable1 country
- Individualised Endometrial Cancer Risk Stratification by Bayesian Prediction Model (ENDORISK), Optimizing Clinical ImplementationRecruitingNCT07200466Not applicable1 country
- Irreversible Electroporation for Recurrent or Metastatic Cervical Lymph Node Metastases From Thyroid Cancer: A Prospective Multicenter Single-Arm StudyRecruitingNCT07328243Not applicable1 country
- Implementation of Indocyanine Green to Identify Sentinel Lymph Nodes During Surgery for Breast CancerRecruitingNCT07146295Not applicable1 country
- MR-guided Single-fraction SBRT for Nodal Oligorecurrent Prostate Cancer (PINPOINT)Not yet recruitingNCT07635108Not applicable1 country
- Safety and Efficacy of NRT6008 in Patients With Unresectable Locally Advanced Pancreatic Cancer (LAPC) and Advanced Pancreatic Cancer With Lymph Node MetastasesRecruitingNCT06278454Phase 11 country
- Distribution and Analysis of Metastatic Lymph Nodes in Colorectal Cancer Patients (DIAMOND)Not yet recruitingNCT073063901 country
- Liquid Biopsy in Early Colorectal LesionsNot yet recruitingNCT073191041 country
- XR-Assisted PET/CT Navigation for Cervical Lymph Node Dissection in Lung CancerNot yet recruitingNCT07593872Not applicable
- Ultrasound-Guided Core Needle Biopsy to Assess Sensitivity and Specificity of Axillary Lymph Node Metastasis in Breast CancerNot yet recruitingNCT07573657
- Comparison of [68Ga]Ga-CTR-FAPI and 18F-FDG PET/MRI for Lymph Node Staging in Rectal CancerNot yet recruitingNCT07552207Not applicable
- Propranolol With Tislelizumab Plus GC in Neoadjuvant Bladder UCEnrolling by invitationNCT07353294Phase 11 country
- Iparomlimab and Tuvonralimab Plus Chemotherapy Before Surgery for Stage III Lung CancerNot yet recruitingNCT07538193Not applicable1 country
- Real-World Study on Efficacy and Influencing Factors of Immunotherapy for Pan-Cancer Lymph Node Metastases.Not yet recruitingNCT075403771 country
- A Phase III Randomised Clinical Trial of Ultrasound Groin Monitoring Versus Groin Lymph Node Dissection to De-Escalate the Extent of Surgery in Vulvar CancerNot yet recruitingNCT06476639Phase 31 country
- The Clinical Significance of Examining Metastatic Lymph Nodes in Individual Gastric Mesenteries in the Patients With Gastric Cancer Undergoing GastrectomyRecruitingNCT071394181 country
- Maximizing Lymph Node Dissection on Fresh and Fixed Lung Cancer Resection SpecimensRecruitingNCT06252129Not applicable1 country
- NODE (groiN ultrasOunD cancEr)RecruitingNCT06264167Not applicable1 country
- Finding Sentinel Lymph Nodes During Mastectomy Using Indocyanine Green (INIGMA Study)RecruitingNCT07362485Not applicable1 country
- LN-RADS, RECIST 1.1 and Node-RADS Classification in the Assessment of Lymph NodesRecruitingNCT06527027Not applicable1 country
- Comparative Study of Transaxillary Robotic Thyroidectomy With MRND Versus Conventional Open Surgery in N1b PTCRecruitingNCT06623578Not applicable1 country
- Development and Prospective Validation of a Digital Pathology-based Artificial Intelligence Diagnostic Model for Pan-cancer Lymphatic MetastasisRecruitingNCT065179791 country
- Survival Effect of Hepato-celiac Lymphadenectomy In Primary or Relapsed Ovarian CancerRecruitingNCT05236686Not applicable1 country
- Sentinel. Ambulatory. Oral Cavity. Oropharynx (S.A.C.O)RecruitingNCT03545256Not applicable1 country
- Incidence of 107 Lymph Node MetastasisRecruitingNCT071651841 country
- Incidence of 106TBL Lymph Node MetastasisRecruitingNCT071652101 country
- Exploration of Lymph Node Metastasis and Tumor Deposit in the Posterior Gastric Mesentery for Distal Gastric CancerRecruitingNCT067368471 country
- Analysis of Lymph Node Metastasis and Tumor Deposit in the Short Gastric Mesentery Following Total Gastrectomy for Gastric CancerRecruitingNCT067288781 country
- Lymph Node Metastasis in Early Esophageal Squamous Cell CarcinomaRecruitingNCT070505761 country
- RET-US Study - Ultrasound-Based Prediction of RET Alterations and Lateral-Neck Metastasis in Thyroid CancerNot yet recruitingNCT070429841 country
- Image-guided Ultrasound Robotic Intraoperative Evaluation of Lymph-nodes Status in Gynecological MalignanciesRecruitingNCT06621823Not applicable1 country
- Adjuvant Immunotherapy Combined With ChemoRadiation for Patients With High-risk Resectable Extrahepatic Cholangiocarcinoma(AICRC)Enrolling by invitationNCT069979131 country
- Predicting Non-small Cell Lung Cancer (NSCLC) Lymph Node Metastasis: Integrating Circulating Tumor DNA (ctDNA) Mutation/ Methylation Profiling With Positron Emission Tomography-computed Tomography (PET-CT) ScanRecruitingNCT063582221 country
- Pilot Study of MPB-2043 Enhanced MRI for Nodal Staging in Head and Neck Squamous Cell CarcinomasRecruitingNCT06540443Phase 11 country
- AI-Based Prediction of Lymph Node Metastasis in Gastric Cancer Using Preoperative Multimodal DataEnrolling by invitationNCT069576781 country
- Radiomics-Based AI Model for Predicting Para-Aortic Lymph Node Metastasis in Gastric Cancer PatientsEnrolling by invitationNCT069470961 country
- Clinical Relevance of Pathologic Regression IN Lymph Node for Locally Advanced Rectal CancerEnrolling by invitationNCT06883084
- Regional Lymph Node Metastasis and Survival Outcomes in Advanced HCCRecruitingNCT068767531 country
- Dutch National Randomized Study: PSMA-PET/CT As a Triage Tool for Pelvic Lymph Node Dissection in Prostatectomy PatientsRecruitingNCT05000827Not applicable1 country
- Targeted Axillary Dissection (TAD) in Early-stage Node Positive Breast CancerRecruitingNCT04671511Not applicable1 country