An interventional study of Pan retinal photocoagulation laser treatment in Proliferative Diabetic Retinopathy, sponsored by University of Malaya. Status unknown at 1 site in Malaysia. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2010-01-08.
Sponsored by University of Malaya · Not applicable, Interventional, and Treatment
The purpose of this study is to measure effectiveness of yellow 577 nm laser compared to conventional green laser 532 nm for diabetic retinopathy in terms of number of treatment sessions required and visual acuity outcome.
The study also compares pain score of patients receiving laser treatment and side effects of laser treatment.
Diabetes mellitus (DM) is a major medical problem throughout the world. The most common and potentially most blinding of these complications is proliferative diabetic retinopathy (PDR).
Panretinal photocoagulation is established as the gold standard of treatment, supported by the data of the Diabetic Retinopathy Study (DRS).This study found that laser treatment reduced the rate of severe visual loss by 50%. Currently the green 532nm laser is the most common wavelength used. However, this conventional green laser has some complications such as pain, vitreous haemorrhage, choroidal effusion and visual field loss.
Due to the complication of conventional lasers, the yellow laser (577 nm)with peak absorption of oxyhemoglobin and good absorption of melanin is postulated to be more effective at producing retinal laser burns with a lower power and less pain compared to the green laser.
815 studies on the registry are indexed under Retinal Diseases; 105 are open to participants now.
This study's planned enrollment of 120 is above the median of 60 across 500 interventional studies indexed under Retinal Diseases.
Browse Retinal Diseases studies →University of Malaya is the lead sponsor of 280 studies on the registry; 55 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Current type of laser used for treatment of proliferative diabetic retinopathy
Procedure: Pan retinal photocoagulation laser treatment
new laser wavelength for treatment of PDR
Procedure: Pan retinal photocoagulation laser treatment
Eyes with PDR are randomised to treatment with either the green laser 532 nm or 577 nm yellow laser.
Also known as: Quantel Supra 577nm laser
Visual acuity measurement by logarithm of the minimum angle of resolution (logMAR)
Time frame: 2 years
Patient pain score during laser procedure
Time frame: 2 years
This study is status unknown, as verified in Jan 2010. You cannot join it, but the record below documents what was studied.
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University of Malaya