CClinicalTrials.gg
CompletedNCT00907855DASI-08-713Updated Nov 30, 2011

Using Duke Activity Status Index (DASI) to Select Optimal Cardiac Stress Tests

An observational study in Ischemic Heart Disease, sponsored by NYU Langone Health. Completed at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2011-11-30.

Sponsored by NYU Langone Health · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
200
Ages
18 Years and older
Sex
All
01

Study summary

Cardiac stress testing with functional nuclear imaging is an invaluable technique in the diagnostic and prognostic evaluation of patients with known or suspected ischemic heart disease. Selection of the appropriate type of nuclear stress test: exercise stress Myocardial Perfusion Imaging (MPI) versus pharmacologic stress MPI is crucial for not only diagnostic accuracy and prognostic evaluation, but also for sound clinical decisions and resource utilization.

The Duke Activity Status Index (DASI) is a 12-item questionnaire that utilized self-reported physical work capacity to estimate peak metabolic equivalents (METs) and has been shown to be a valid measurement of functional capacity. The investigators hypothesized that the DASI may be the screening tool that evaluates functional capacity and guides selection of the optimal stress MPI study.

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Conditions studied

  • Ischemic Heart Disease

Keywords

  • Ischemic Heart Disease
  • Duke Activity Status Index
  • Stress Myocardial Perfusion Imaging
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In context

Heart Diseases

3,640 studies on the registry are indexed under Heart Diseases; 461 are open to participants now.

This study's enrollment of 200 is below the median of 294 across 1,241 observational studies indexed under Heart Diseases.

Browse Heart Diseases studies →

Lead sponsor

NYU Langone Health is the lead sponsor of 1,390 studies on the registry; 253 are open to participants now.

Of its 227 completed or terminated interventional studies of FDA-regulated products, 191 (84%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients referred by their primary physician to the Nuclear Lab at NYU School of Medicine for stress myocardial perfusion imaging testing.

Inclusion criteria

  • Age > 18

Exclusion criteria

Exclusion Criteria:

  • None
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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
200 participants (actual)
06

Study locations

1 site
  • Nuclear Cardiology/Stress Lab, NYU Cardiology Division
    New York, New York 10016, United States
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References and documents

Publications

  • Shaw LJ, Olson MB, Kip K, Kelsey SF, Johnson BD, Mark DB, Reis SE, Mankad S, Rogers WJ, Pohost GM, Arant CB, Wessel TR, Chaitman BR, Sopko G, Handberg E, Pepine CJ, Bairey Merz CN. The value of estimated functional capacity in estimating outcome: results from the NHBLI-Sponsored Women's Ischemia Syndrome Evaluation (WISE) Study. J Am Coll Cardiol. 2006 Feb 7;47(3 Suppl):S36-43. doi: 10.1016/j.jacc.2005.03.080. PubMed 16458169 ↗
  • Hlatky MA, Boineau RE, Higginbotham MB, Lee KL, Mark DB, Califf RM, Cobb FR, Pryor DB. A brief self-administered questionnaire to determine functional capacity (the Duke Activity Status Index). Am J Cardiol. 1989 Sep 15;64(10):651-4. doi: 10.1016/0002-9149(89)90496-7. PubMed 2782256 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Nov 30, 2011, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT00907855
Lead sponsor
NYU Langone Health
Collaborators
Astellas Pharma Inc
Responsible party
Lawrence Phillips, MD (Director, Nuclear Cardiology, NYU Langone Health) — Principal investigator
First posted
May 25, 2009
Start date
Apr 2009
Last update
Nov 30, 2011

Study contacts

Jennifer H. Mieres, MD
principal investigator · Division of Cardiology, New York University School of Medicine
Lawrence Phillips, MD
study director · Division of Cardiology, New York University School of Medicine

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Nov 2011. You cannot join it, but the record below documents what was studied.

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