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TerminatedNCT00615329Updated Nov 25, 2014

Huntsman Biopsy Study

An observational study in Soft Tissue Sarcoma and Osteosarcoma, sponsored by State University of New York - Upstate Medical University. Terminated at 1 site in United States. Per ClinicalTrials.gov, last updated 2014-11-25.

Sponsored by State University of New York - Upstate Medical University · Observational

Why this study was terminated
Huntmans Cancer Institute terminated study
Study type
Observational
Model
Case-only
Time perspective
Prospective
Enrollment
142
Sex
All
01

Study summary

Bone and soft tissue sarcomas are currently classified based upon light microscopy supplemented by immunohistochemistry, but within many if not all of these tumor histologic types, considerable heterogeneity exists not only in microscopic appearance but also in biologic behavior and prognosis. Progress in the directed treatment of these tumors, particularly the sarcomas, awaits characterization of the gene profiles for these tumors. Orthopedic oncology researchers at Huntsman Cancer Institute at the University of Utah are establishing a tumor bank for this purpose. The long term objectives of this work include:

  1. creating tumor specific gene profiles to improve diagnostic accuracy
  2. performing gene set validation for diagnostic predictive power
  3. defining a discriminate gene list implicated in pathogenesis

The tissue procured under this protocol at SUNY Upstate Medical University will be limited to excess soft tissue and bone tumor tissue from patients otherwise undergoing clinically indicated procedures for diagnosis or treatment under the care of the local principal investigator (PI) and will be forwarded to the central investigator, R. Lor Randall, MD at Huntsman Cancer Institute for use in the characterization of the gene profiles of these tumors.

Read the detailed description

as stated in brief summary

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Conditions studied

  • Soft Tissue Sarcoma
  • Osteosarcoma

Keywords

  • Create tumor specific gene profiles to improve diagnostic accuracy
  • Perform gene set validation for diagnostic predictive power
  • Define deviant gene list implicated in pathogenesis
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In context

Sarcoma

1,667 studies on the registry are indexed under Sarcoma; 393 are open to participants now.

This study's enrollment of 142 is above the median of 121 across 238 observational studies indexed under Sarcoma.

Browse Sarcoma studies →

Lead sponsor

State University of New York - Upstate Medical University is the lead sponsor of 154 studies on the registry; 17 are open to participants now.

Of its 11 completed or terminated interventional studies of FDA-regulated products, 4 (36%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

All patients who present to Doctor Damron for care relating to a bone or soft tissue tumor that has been established to be or is suspected to possibly be a sarcoma AND who will require a diagnostic or therapeutic surgical procedure which will result in procurement of tissue for histologic review will be approached in the consent process.

Inclusion criteria

  • Bone or soft tissue tumor that has been established to be or is suspected to possibly be a sarcoma AND who will require a diagnostic or therapeutic surgical procedure which will result in procurement of tissue for histologic review

Exclusion criteria

Exclusion Criteria:

  • Non cancer patients
05

Study design

Observational model
Case-only
Time perspective
Prospective
Enrollment
142 participants (actual)
Biospecimen retention
Samples with dna

Groups and cohorts

  • Soft tissue tumor

    Any patient with soft tissue tumor will be asked to give a sample for this study

06

What researchers measure

Primary outcomes

  1. Classification of sarcomas

    sarcomas will be classified by researchers at Huntsman Institute

    Time frame: Upon collection/analysis of sarcoma

07

Study locations

1 site
  • SUNY Upstate Medical University
    Syracuse, New York 13202, United States
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Nov 25, 2014, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT00615329
Lead sponsor
State University of New York - Upstate Medical University
Collaborators
Huntsman Cancer Institute
Responsible party
Timothy Damron, M.D. (Associate Professor, State University of New York - Upstate Medical University) — Principal investigator
First posted
Feb 14, 2008
Start date
Apr 2003
Primary completion
Feb 2014
Completion
Feb 2014
Last update
Nov 25, 2014

Study contacts

Timothy A Damron, MD
principal investigator · State University of New York - Upstate Medical University

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is terminated, as verified in Nov 2014. You cannot join it, but the record below documents what was studied.

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