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WithdrawnNCT00506701Updated Mar 18, 2015

Effect of Tadalafil in Chronic Obstructive Lung Disease Patients Suffering From Secondary Pulmonary Hypertension

An interventional study of Tadalafil in Chronic Obstructive Lung Disease, sponsored by Herlev Hospital. Withdrawn at 1 site in Denmark. Open to participants aged 45 Years to 85 Years. Per ClinicalTrials.gov, last updated 2015-03-18.

Sponsored by Herlev Hospital · Not applicable, Interventional, and Treatment

Why this study was withdrawn
due to lack of finance
Phase
Not applicable
Study type
Interventional
Enrollment
0
Allocation
Not applicable
Ages
45 Years to 85 Years
Sex
All
01

Study summary

Tadalafil may lower the pulmonary artery pressure in patients with Chronic Obstructive Lung Disease and secondary pulmonary hypertension and thereby improve patients quality of life.

Read the detailed description

Twenty outpatients with Chronic Obstructive Lung Disease (COPD) and secondary pulmonary hypertension are treated in a cross-over design with Tadalafil or placebo for 4 weeks. Primary effect parameter is 6 min. walking test.

02

Conditions studied

03

In context

Lung Diseases

3,303 studies on the registry are indexed under Lung Diseases; 355 are open to participants now.

Browse Lung Diseases studies →

Lead sponsor

Herlev Hospital is the lead sponsor of 195 studies on the registry; 25 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
45 Years to 85 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Clinical diagnosis of Chronic obstructive lung disease

Exclusion criteria

Exclusion Criteria

  • Patients with asthma
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
Triple (Participant, Care provider, Investigator)
Enrollment
0 participants (actual)

Study arms

  • Experimental
    Tadalafil treatment 40 mg

    Drug: Tadalafil

Interventions

  • DrugTadalafil

    40 mg tablet

    Also known as: PDE5 inhibitor

06

What researchers measure

Primary outcomes

  1. Change in 6 min. walking test

    Time frame: 6 months

07

Study locations

1 site
  • Herlev University Hospital
    Herlev, DK-2730, Denmark
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 18, 2015, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00506701
Lead sponsor
Herlev Hospital
First posted
Jul 25, 2007
Start date
Feb 2008
Primary completion
Feb 2010
Completion
Feb 2010 (estimated)
Last update
Mar 18, 2015

Study contacts

Lars C Laursen, MD
principal investigator · University of Copenhagen

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is withdrawn, as verified in Jul 2007. You cannot join it, but the record below documents what was studied.

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