An interventional study of prednisolone 1% and ketorolac 0.5% in Primary Open Angle Glaucoma and Pseudoexfoliation Glaucoma, sponsored by Queen's University. Completed at 1 site in Canada. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2015-09-23.
Sponsored by Queen's University · Not applicable, Interventional, and Treatment
The type of anti-inflammatory medication used post selective laser trabeculoplasty (SLT) may have an impact on the intra-ocular pressure (IOP) lowering effect of SLT. This study will evaluate the IOP lowering effect of SLT following the topical administration of one of the following: prednisolone 1%, ketorolac 0.5% or artificial tears.
Patients who have been chosen to undergo SLT for glaucoma will be randomized to receive one of prednisolone 1%, ketorolac 0.5% or artificial tears four times a day for 5 days following administration of the laser treatment. The IOP will be measured at various time points following SLT: 1 hour, 2 days, 1 week, 1 month, 3 months, 6 months, and 1 year.
1,818 studies on the registry are indexed under Glaucoma; 231 are open to participants now.
This study's enrollment of 120 is above the median of 65 across 1,272 interventional studies indexed under Glaucoma.
Browse Glaucoma studies →Queen's University is the lead sponsor of 199 studies on the registry; 16 are open to participants now.
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Exclusion Criteria:
Prednisolone 1% eye drop
Drug: prednisolone 1%
ketorolac 0.5% eye drop
Drug: ketorolac 0.5%
Artificial Tears (methyl cellulose eye drop)
Drug: Artificial Tears (Methyl cellulose drops)
eye drop once in each eye treated, 4 times / day for 5 days post-laser
eye drop once in each eye treated, 4 times / day for 5 days post-laser
Also known as: Acular
eye drop once in each eye treated, 4 times / day for 5 days post-laser
Also known as: Refresh Tears
Intraocular pressure lowering effect
Time frame: 1 hour, 2 days, 1 month, 3 months, 6 months and 1 year
intraocular pressure elevation
Time frame: 1 hour, 2 days, 1 month
This study is completed, as verified in Sep 2015. You cannot join it, but the record below documents what was studied.
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