Exfoliation Syndrome clinical trials
The registry lists 72 studies for Exfoliation Syndrome across more than 10 countries. 20 are recruiting or about to start. 32 of them are mainly about Exfoliation Syndrome (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-13.
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Who runs them
Aristotle University Of Thessaloniki (5) · St. Erik Eye Hospital (4) · Assiut University (4) · Medical University of Vienna (3) · Vastra Gotaland Region (3) · Wills Eye (2) · Davinci LTD (2) · Kata Culina (2)
What is being tested here
Drugs under test in Exfoliation Syndrome studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Travoprost | 1 | 0 | 2 |
| Bromfenac | 0 | 0 | 1 |
| AR-12286 | 0 | 0 | 1 |
| Triamcinolone Acetonide | 0 | 1 | 1 |
| Triamcinolone | 0 | 1 | 1 |
| Prednisolone | 0 | 0 | 1 |
| Ketorolac | 0 | 0 | 1 |
| Brinzolamide | 0 | 0 | 1 |
| Brimonidine | 0 | 0 | 1 |
| Timolol | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 2
- Mar 2027The Correlation Between Pupil Size and Retinal Nerve Fibers Changes in Pseudoexfoliation Syndrome. · Assiut University
- Mar 2027Vitamin Mix (B6, B9, B12, And Choline) For Glaucoma Patients · Karolinska Institutet
Who these studies take
Of the 13 Exfoliation Syndrome studies recruiting now, 6 (46%) set no upper age limit and 0 (0%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (15%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 4 (31%) | 4 (31%) |
| 30 | 5 (38%) | 5 (38%) |
| 40 | 8 (62%) | 8 (62%) |
| 50 | 11 (85%) | 11 (85%) |
| 65 | 13 (100%) | 13 (100%) |
| 75 | 13 (100%) | 13 (100%) |
| 85 | 12 (92%) | 12 (92%) |
Across all 72 studies, recruiting or not: 3% stop at 75 or younger and 0% at 65; 10% take children; 0% are for women only and 0% for men only; 22% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 50 of 72. Browse all 72 → or search them.
- Topical Insulin for Glaucoma (TING2)Enrolling by invitationNCT07619482Phase 1/21 country
- Corneal Biomechanics and Surgically Induced Astigmatism in Pseudoexfoliation SyndromeRecruitingNCT077222471 country
- Influence of Cataract Surgery on Corneal Biomechanical Properties in Patients With Pseudoexfoliation SyndromeNot yet recruitingNCT077191011 country
- Transcorneal Electrical Stimulation for the Treatment of Visual Field Defects in Patients With Open-Angle GlaucomaRecruitingNCT06682962Not applicable1 country
- The Safety and Efficacy of Direct SLT in Pseudoexfoliation GlaucomaNot yet recruitingNCT07401290Not applicable1 country
- Standalone iStent Infinite and iDose TR for Management of Moderate to Severe Open Angle GlaucomaRecruitingNCT07228221Phase 41 country
- Optimal Treatment Protocol for Selective Laser Trabeculoplasty - Repeat TrialEnrolling by invitationNCT05159960Not applicable1 country
- XEN Glaucoma Gel Stent Versus TrabeculectomyRecruitingNCT05439161Not applicable1 country
- Investigating the Genetic Basis of Pseudoexfoliation Syndrome, Angle-closure Glaucoma and Primary Open-angle GlaucomaRecruitingNCT034237581 country
- Vitamin Mix (B6, B9, B12, And Choline) For Glaucoma PatientsRecruitingNCT06885827Not applicable1 country
- Trabeculopuncture as Predictive Test for the Success of Ab Interno TrabeculectomyRecruitingNCT06523751Not applicable1 country
- Corneal Biomechanics, Optical Properties and Anterior Segment Structural Features in Patients With PseudoexfoliationRecruitingNCT067315301 country
- Uddevalla Skövde Transscleral Micropulse StudyEnrolling by invitationNCT055577211 country
- Long-term Safety and Efficacy of a Modified Suprachoroidal Silicone Tube (SST) ShuntRecruitingNCT066915551 country
- The Correlation Between Pupil Size and Retinal Nerve Fibers Changes in Pseudoexfoliation Syndrome.Not yet recruitingNCT06588816
- Phacoemulsification vs SLT as Initial Treatment for Pseudoexfoliation GlaucomaRecruitingNCT04416724Not applicable1 country
- Safety and Efficacy of Suprachoroidal Tube Shunt in Patients With Primary Open and Pseudoexfoliation GlaucomasRecruitingNCT061543301 country
- Outcome of Two Surgical Methods for IOLImplantation in Eyes With Pseudoexfoliation SyndromeRecruitingNCT06053554Not applicable1 country
- INTEGRAL Study: A Longitudinal Study of Surgeries and Lasers in Glaucoma: Long-term Results and Success Predictors Analysed From a Large-scale Retrospective and Prospective Glaucoma RegisterEnrolling by invitationNCT043816111 country
- Comparison Of iStent to Laser in Exfoliation Glaucoma Helsinki Study GroupRecruitingNCT04635020Not applicable1 country
- Optimal Treatment Protocol for Selective Laser TrabeculoplastyActive, not recruitingNCT03798223Not applicable1 country
- Pseudoexfoliation and Carpal Tunnel StudyCompletedNCT069460301 country
- Vitreous Proteomics of Patients Suffering From Pseudoexfoliation SyndromeActive, not recruitingNCT07506551Not applicable1 country
- Bromfenac to Reduce Inflammation in Patients With Pseudoexfoliation Syndrome After Cataract SurgeryCompletedNCT02137161Phase 41 country
- Real World Evidence of Xen45 Gel Implant in Pseudoexfoliation GlaucomaCompletedNCT069933111 country
- Safety and Effectiveness of the Hydrus MicrostentTerminatedNCT05198297Not applicable1 country
- Scleral Fixation for Intraocular Lens-Bag DislocationCompletedNCT064230791 country
- Genetic and Risk Factors in Exfoliation Glaucoma PatientsCompletedNCT062377641 country
- Pseudoexfoliation Syndrome, Sarcopenia and Chronic PainCompletedNCT061211541 country
- Corneal Endothelium After Phacoemulsification in Pseudo Exfoliation SyndromeCompletedNCT05447130Not applicable1 country
- Correlation Between Pupil Size and Ocular Signs of Pseudoexfoliation SyndromeCompletedNCT051131211 country
- Cataract Surgery in Patients With Pseudoexfoliation and Pseudoexfoliation GlaucomaStatus unknownNCT04590651Not applicable1 country
- Impact of Self-tonometry on Glaucoma Treatment Decision.CompletedNCT048881561 country
- The Possible Association Between Pseudoexfoliation Syndrome And Corneal Endothelial Cell ChangesStatus unknownNCT051561381 country
- Efficacy and Safety of Lens Extraction in Patients With Pseudoexfoliation GlaucomaCompletedNCT03494465Not applicable1 country
- iCare® Home vs Goldmann Applanation TonometryCompletedNCT049113871 country
- IOP Monitoring After Trabeculectomy Using iCare HomeTerminatedNCT034458061 country
- Monitoring of the IOP After SLT Using iCare HomeStatus unknownNCT033107881 country
- Adherence With Fixed Versus Unfixed Glaucoma TherapyCompletedNCT012810201 country
- Prevalence of Ocular Surface Disease in Malaysian Glaucoma PatientsStatus unknownNCT04609345
- The Oscillation of Crystalline and Intraocular LensesStatus unknownNCT042746341 country
- Intraocular Pressure After Preserflo / Innfocus Microshunt Implantation vs TrabeculectomyStatus unknownNCT04440527Not applicable1 country
- Changes in Ocular Rigidity After Trabeculectomy in Patients With POAGCompletedNCT02544646Not applicable1 country
- The Efficacy of Citicoline in Eyedrops (OMK1) in Reducing the Progression of GlaucomaCompletedNCT04020705Not applicable
- A Prospective Study to Assess the Hypotensive Efficacy of Rho-Kinase Inhibitor AR-12286 Ophthalmic Solution 0.5% and 0.7% in Patients With Exfoliation Syndrome and Ocular Hypertension or GlaucomaCompletedNCT01936389Phase 21 country
- Will the Use of Triesence During Glaucoma Surgery Provide Lower Eye Pressure and Improve the Results of the Surgery?CompletedNCT00853905Phase 2/31 country
- The Endothelial Count in PxfStatus unknownNCT03265457
- Micropulse Laser Trabeculoplasty as Adjunctive Treatment in Patients With Pseudoexfoliation GlaucomaCompletedNCT03483402Not applicable
- Long-term Intraocular Lens (IOL) Decentration and Tilt in Eyes With Pseudoexfoliation Syndrome (PES) Following Cataract SurgeryCompletedNCT03453827
- AqueSys XEN 45 Glaucoma Implant in Refractory GlaucomaCompletedNCT02036541Not applicable1 country