An interventional study of Dapsone in Pneumonia, Pneumocystis Carinii and HIV Infections, sponsored by Jacobus Pharmaceutical. Completed at 1 site in United States. Open to participants aged 12 Years and older. Per ClinicalTrials.gov, last updated 2005-06-24.
Sponsored by Jacobus Pharmaceutical · Not applicable, Interventional, and Treatment
Among 62 studies in Pneumonia, Pneumocystis with a site in United States — none open to participants now, none under way, none of them phase 3. Pneumonia, Pneumocystis · United States.
Among the 62 studies in Pneumonia, Pneumocystis with a site in United States, this one is one of 23 with no phase, and was the 1st registered.
108 studies on the registry are indexed under Pneumonia, Pneumocystis; 16 are open to participants now.
Browse Pneumonia, Pneumocystis studies →None of the 62 studies in Pneumonia, Pneumocystis with a site in United States is open now. The open studies under Pneumonia, Pneumocystis, anywhere →
Of the 9 Pneumonia, Pneumocystis studies recruiting now, 6 set no upper age limit and 1 stops at 75 or younger; 1 takes children under 18; 1 takes healthy volunteers.
This study: 12 Years and older · all sexes · no healthy volunteers.
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62 studies; the count open now beside each. This study's row is marked.
First in 1994; this study’s year is marked.
By drug class, each counting the studies that test any of its medicines:
Median enrollment 108 across the 34 interventional studies, 407 across the 7 observational. Of the 60 that completed or were terminated, 0 (0%) have results posted.
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22 of 62 have an industry lead sponsor. The 10 most frequent:
Jacobus Pharmaceutical is the lead sponsor of 6 studies on the registry; none are open to participants now.
Jacobus Pharmaceutical has 2 studies filed under Pneumonia, Pneumocystis — fewer than ten, so there is no comparison to draw.
None of the studies under way reaches primary completion within a year.
Among the 62 studies in Pneumonia, Pneumocystis with a site in United States, from their registry updates:
Nothing recorded among them since 2026-09-25.
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To determine which of 2 doses of dapsone is effective prophylaxis for Pneumocystis carinii pneumonia (PCP) in patients with oral thrush or hairy leukoplakia and less than 400 CD4 lymphocytes per mm3. To determine whether the long-term toxicities associated with daily dapsone in this population are tolerable.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
The patient must have positive antibody test and presence of oral thrush or hairy leukoplakia.
Exclusion Criteria
Co-existing Condition:
Patients with the following are excluded:
Concurrent Medication:
Excluded:
Patients with the following are excluded:
Prior Medication:
Excluded:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The human immunodeficiency virus, which weakens the immune system.
Many studies now accept people whose HIV is controlled on treatment, judged by the viral load and the CD4 count. Check the limits this study sets.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
An allergy, or another reaction of the immune system, to a substance. “Hypersensitivity to the study drug” means a known allergic reaction to it — not every side effect a medicine can have.
HIV
The human immunodeficiency virus, which weakens the immune system.
Many studies now accept people whose HIV is controlled on treatment, judged by the viral load and the CD4 count. Check the limits this study sets.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Hypersensitivity
An allergy, or another reaction of the immune system, to a substance. “Hypersensitivity to the study drug” means a known allergic reaction to it — not every side effect a medicine can have.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
This study is completed, as verified in Dec 1989. You cannot join it, but the record below documents what was studied.
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Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Studies of the drug tested here: Dapsone
Jacobus Pharmaceutical