University of Cape Town: all 116 studies

Page 1 of 2. Open to participants first (14), then studies with results posted, then the rest; newest registration first within each.

• The Coach Mpilo Study: Evaluation of a Peer-led Intervention to Promote Engagement in HIV Care for Men Living With HIVNot yet recruitingNCT07564193Not applicable
• Choice-Based Support for Adults Starting or Restarting Antiretroviral Therapy in Cape Town, South AfricaNot yet recruitingNCT07439562Not applicable
• '5 Rs to Rescue' A Cluster Trial With an Embedded Process EvaluationRecruitingNCT06997328
• Vaginal Microbiome Research Consortium for AfricaRecruitingNCT06662747
• B.R.A.I.N in People Living With HIV StudyRecruitingNCT06466642Not applicable
• Evaluation of a 2-session Parent Training Programme for Caregivers of Younger Children in ZimbabweNot yet recruitingNCT06431321Not applicable
• Same Day Diagnosis of Extrapulmonary TB (TB Serositis and TB Meningitis).RecruitingNCT06135818Not applicable
• B. Infantis Supplementation to Improve Immunity in Infants Exposed to HIVRecruitingNCT05923333Not applicable
• Point-of-care Ultrasound Abnormalities in EclampsiaRecruitingNCT05678062Not applicable
• Gene Expression Profiles in Spinal Tuberculosis.RecruitingNCT05610098
• Evaluating Acid Reflux After Oesophageal Stenting Using Anti-reflux StentsRecruitingNCT05303298Not applicable
• Test to Treat TB: Impact of Sputum Sequencing-guided Individualised Therapy on Outcomes in Drug-resistant TuberculosisNot yet recruitingNCT05007795Not applicable
• Remote Ischaemic Conditioning in STEMI Patients in AFRICARecruitingNCT04813159Not applicable
• Atorvastatin to Reduce Inflammation After Tuberculosis Treatment CompletionRecruitingNCT04147286Phase 2/3
• Tenofovir-lamivudine-dolutegravir Combination as Second-line ART: a Randomised Controlled TrialCompletedNCT03991013Phase 2Results posted
• Standard Versus Double Dose Dolutegravir in Patients With HIV-associated TuberculosisCompletedNCT03851588Phase 2Results posted
• Early Versus Delayed BCG Vaccination of HIV-exposed InfantsCompletedNCT02062580Phase 2Results posted
• Antibiotic Efficacy in Pneumonitis Following Paraffin (Kerosene) Ingestion in ChildrenCompletedNCT01253980Not applicableResults posted
• Typing of Human Papilloma Virus (HPV) From Female Genital WartsCompletedNCT01192282Results posted
• Implementation Study With Embedded RCT of a Digital System of Parenting Support Within Government Services in South AfricaActive, not recruitingNCT07814261Not applicable
• Childhood Adversity, Inflammatory Reactivity and Persistent PainCompletedNCT06127693
• The African Critical Illness Outcomes StudyCompletedNCT06051526
• Comparing a Novel Point-of-care Cytokine Biomarker Lateral Flow Test With Nucleic Acid Amplification Tests for Detection of Sexually Transmitted Infections and Bacterial VaginosisCompletedNCT05723484
• South African Paediatric Surgical Outcomes Study 2CompletedNCT05681871Phase 4
• Point-of-care Ultrasound Abnormalities in Early Onset PreeclampsiaStatus unknownNCT05662995Not applicable
• Evaluating the Impact of Computer-assisted X-ray Diagnosis and Other Triage Tools to Optimise Xpert Orientated Community-based Active Case Finding for TB and COVID-19Active, not recruitingNCT05220163Not applicable
• Cardiovascular Outcomes and Mortality in Vascular Surgical PatientsCompletedNCT05208957
• Iron Deficiency Anaemia in Pregnant Patients Presenting for Antenatal CareCompletedNCT05157828
• Health System Dynamic & Resource Requirement in a South African COVID-19 Field HospitalCompletedNCT05113875
• Testing New Strategies for Patients Hospitalised With HIV-associated Disseminated TuberculosisActive, not recruitingNCT04951986Phase 3
• the PrEsentation, Rationale and Impact of reperFUSION for Acute Coronary Syndromes in Cape Town and the Garden Route Health District - the PERFUSION RegistryCompletedNCT04887571
• An Observational Study of Distress, Immune Function, and Pain in HIV.CompletedNCT04757987
• Catalysing the Containment of COVID-19TerminatedNCT04523090Phase 2/3
• High vs. Standard Dose Rifampicin for Effusive Tuberculous PericarditisCompletedNCT04521803Phase 2
• African Covid-19 Critical Care Outcomes StudyStatus unknownNCT04367207
• Chloroquine Outpatient Treatment Evaluation for HIV-Covid-19WithdrawnNCT04360759Phase 3
• Telemedicine for First Trimester Abortion in South AfricaStatus unknownNCT04336358Not applicable
• Xpert Active Case-finding Trial 3 (XACT-3)CompletedNCT04303104Not applicable
• BNP Evaluation Before Surgery Study: an Observational Study of Natriuretic Peptide Levels Prior to Surgery.CompletedNCT04114032
• Peer Support to Mitigate the Impact of Stigma in Young HIV+ Pregnant & Postpartum WomenCompletedNCT04036851Not applicable
• The ASOS-2 Trial Maternal Mortality Sub-studyStatus unknownNCT04029207
• Linezolid, Aspirin and Enhanced Dose Rifampicin in HIV-TBMCompletedNCT03927313Phase 2
• Hypertension And Surgery Study: Evaluating the Implementation of a Hypertension Guideline ProtocolCompletedNCT03921086Not applicable
• Enhanced Recovery After Trauma SurgeryStatus unknownNCT03920163Not applicable
• Clinical Evaluation of Adjusted Doses of Darunavir/Ritonavir With Rifampicin in HIV-infected VolunteersTerminatedNCT03892161Phase 1
• A Snapshot Study of Patients Affected by Gunshot Related Injuries in Trauma in South AfricaCompletedNCT03854591
• African Surgical OutcomeS-2 (ASOS-2) TrialCompletedNCT03853824Not applicable
• MethOxyflUraNe at moderaTe High AltItudes for PAIN ManagementStatus unknownNCT03849027Phase 4
• Pharmacometrics to Advance Novel Regimens for Drug-resistant Tuberculosis-PandrTB TuberculosisStatus unknownNCT03827811
• Self-expandable Metal Stents Versus Multiple Plastic Stents for Palliation of Biliary ObstructionStatus unknownNCT03821025Not applicable
• Childhood Convulsive Status Epilepticus Management In A Resource Limited SettingCompletedNCT03650270Phase 3
• Study of Hip and Knee Arthroplasty in South AfricaCompletedNCT03540667
• Immediate Versus Delayed IUD Insertion After Second Trimester Medical AbortionCompletedNCT03505047Not applicable
• COMparison of Portable Fingertip Versus Conventional Pulse OximeteRs TrialCompletedNCT03496493
• Single-dose Novel Selective alpha2c Antagonist Pharmaco-MRI Study in Healthy VolunteersCompletedNCT03440021Phase 1
• Endotracheal Dilator to Improve OxygenationStatus unknownNCT03411928Not applicable
• Prevalence of Hyperglycemia and Anaemia in Elective Surgical PatientsCompletedNCT03318055
• The Hope Soap Study: a Hand-washing Intervention Among Children in South AfricaCompletedNCT03280771Not applicable
• Postpartum Adherence Clubs for Antiretroviral TherapyCompletedNCT03200054Not applicable
• Timing of Referral to Adherence Clubs for Antiretroviral TherapyCompletedNCT03199027Not applicable
• Xpert Active Case-finding Trial 2: Community-based Active Case-finding for Tuberculosis in South AfricaCompletedNCT03168945Not applicable
• Prevalence of Hypertensive Disease in Patients Presenting for Elective Surgery in the Western Cape, South AfricaCompletedNCT03157661
• Left Cardiac Sympathetic Denervation for Cardiomyopathy Feasibility Pilot StudySuspendedNCT03071653Phase 2
• The Bioavailability of Rifampicin in (FDCs) Widely Used in South Africa to Treat Drug-susceptible (TB)CompletedNCT02953847Phase 1
• Modified Endotracheal Balloon Dilator to Improve Patient Oxygenation and Allow Ventilation During Airway ProceduresCompletedNCT02796326Not applicable
• The Correlate of Risk Targeted Intervention StudyStatus unknownNCT02735590Phase 2/3
• Pharmacometric Optimization of Second Line Drugs for MDR Tuberculosis TreatmentCompletedNCT02727582
• Acid-Base and Point of Care Ultrasound in Severe PreeclampsiaCompletedNCT02721771
• The Impact of Obesity on Cardiac Function in PregnancyCompletedNCT02677558
• IMPI 2 - A Trial of Intrapericardial Alteplase in Large Pericardial EffusionStatus unknownNCT02673879Phase 3
• An Open-label RCT to Evaluate a New Treatment Regimen for Patients With Multi-drug Resistant TuberculosisCompletedNCT02454205Phase 2/3
• iLink (Incentives for Linkage to ART) Study: A Mixed-methods Study to Improve Linkage to HIV CareStatus unknownNCT02440386Not applicable
• Collaborative Care for the Detection and Management of Depression Among Adults Receiving Antiretroviral Therapy in South AfricaCompletedNCT02407691Not applicable
• Task Sharing for the Care of Severe Mental Disorders in a Low-income CountryCompletedNCT02308956Phase 3
• The Pan African Pulmonary Hypertension Cohort StudyCompletedNCT02265887
• Sub-project: Use of Small Implantable ECG Recorder in Pregnant Women With ArrhythmiaStatus unknownNCT02249195
• Use of Low Sensitivity Pregnancy Test for Self-assessment of Medical AbortionCompletedNCT02231619Not applicable
• The Role of Melatonin in the Effective Attainment of Sleep Electroencephalograms (EEG) in ChildrenCompletedNCT02195661Phase 3
• A Trial Of Intravenous N-Acetylcysteine In The Management Of Antituberculous Drug-Induced HepatitisCompletedNCT02182167Phase 2/3
• The Sinovuyo Caring Families Project: a Randomized Controlled Trial of a Parenting ProgrammeCompletedNCT02165371Not applicable
• Evaluation of the Parent Centre's Positive Parenting Skills Training.CompletedNCT02141048Not applicable
• VATS ( Video-Assisted Thoracoscopy) Compared to Reinsertion of a Thoracostomy Tube for Persistent HaemothoraxCompletedNCT02014077Not applicable
• The Utility of Intensified Case Finding Combined With a Package of Novel TB Diagnostics Using a Mobile Clinic in AfricaCompletedNCT01990274Not applicable
• Task Sharing Counseling Intervention by Community Health Workers for Prenatal Depression in South AfricaCompletedNCT01977326Not applicable
• Pregnancy-Related Obesity Prevention Through Education & Communication Technology in AFRICA:The PROTECT-AFRICA STUDYStatus unknownNCT01948323Not applicable
• Strategies to Optimize Antiretroviral Therapy Services for Maternal & Child Health: the MCH-ART StudyCompletedNCT01933477Not applicable
• Preventing TB-IRIS in High-risk Patients: a Randomized Placebo-controlled Trial of PrednisoneCompletedNCT01924286Phase 3
• 4-question "RACY" Delirium Screening Tool Validation StudyCompletedNCT01916889Not applicable
• Impact of Medical Follow-up Discharge PackageWithdrawnNCT01916876Not applicable
• Bi Treatment With Hydralazine/Nitrates Versus Placebo in Africans Admitted With Acute Heart FailureStatus unknownNCT01822808Phase 3
• Sinovuyo Caring Families Project - Pilot TrialCompletedNCT01802294Phase 1
• A Trial of the Urine LAM Strip Test for TB Diagnosis Amongst Hospitalized HIV-infected PatientsCompletedNCT01770730Not applicable
• Study Comparing the Effectiveness of Incentives on Physical Activity Behavior in a Health Insured PopulationCompletedNCT01652950Not applicable
• Optimal Dosing of 1st Line Antituberculosis and Antiretroviral Drugs in Children (a Pharmacokinetic Study)CompletedNCT01637558Phase 4
• Impact of Employee Wellness ProgrammeCompletedNCT01625039Not applicable
• Trial of Point-of-treatment Xpert MTB/RIF AssayCompletedNCT01554384Not applicable
• Utility of Sputum Induction and Novel Technologies to Improve TB Diagnosis in a High HIV Prevalence Primary Care SettingCompletedNCT01545661Not applicable
• Gene Xpert Diagnosis of TB Using Tracheal Aspirates From Intensive Care Unit (ICU) PatientsCompletedNCT01530568Not applicable
• Randomised Trial of Two Educational Intervention for Improving Evidence-based Practice Knowledge, Atttitudes and PracticeCompletedNCT01512823Not applicable
• Working on Wellness (WOW) InterventionStatus unknownNCT01494207Not applicable

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