National Institutes of Health: Infections trials

The registry lists 375 Infections studies with National Institutes of Health as lead sponsor. 16 are open to participants now and 43 have results posted.

Phase 1 89Phase 2 100Phase 3 47Phase 4 7No phase 144(a study in two phases counts in both)

Studies

Page 3 of 4. Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Inflammation, Infection, and Future Cardiovascular RiskCompletedNCT00005496
• Retrovirus Epidemiology Donor Study I (REDS I)CompletedNCT00005278
• Pediatric Pulmonary and Cardiovascular Complications of Vertically Transmitted HIV Infection (P2C2)CompletedNCT00005274
• Pulmonary Complications of HIV Infection Study (PACS)CompletedNCT00005273
• Observing Patients With Early HIV InfectionCompletedNCT00005020
• Oral Manifestations of Human Immunodeficiency Virus Infection in High Risk GroupsCompletedNCT00004781
• Randomized Placebo-Controlled Study of Aerobic Exercise and Resistance Training Plus Megestrol Acetate for HIV-WastingCompletedNCT00004664Not applicable
• Phase I/II Study of Human Anti-Cytomegalovirus (CMV) Monoclonal Antibody MSL-109 in Newborns With Symptomatic Congenital CMV Infection Without Central Nervous System DiseaseCompletedNCT00004642Phase 1/2
• Multicenter Study of Nontuberculous Mycobacteria in Cystic Fibrosis PatientsCompletedNCT00004296
• Phase III Randomized, Controlled Study of Ganciclovir for Symptomatic Congenital Cytomegalovirus InfectionCompletedNCT00004278Phase 3
• Phase II Placebo Controlled Study of Thalidomide in Patients With Mycobacterial and HIV InfectionsCompletedNCT00004276Phase 2
• Comparison of Two Test Methods-NASBA and Antigenemia-for Detecting Cytomegalovirus InfectionCompletedNCT00001976
• Comparing the Effectiveness of Fluconazole and a New Medicine (FK463) in Preventing Fungal Infections in Bone Marrow Transplant PatientsCompletedNCT00001937Phase 3
• Interleukin-12 in the Treatment of Severe Nontuberculous Mycobacterial InfectionsCompletedNCT00001911Phase 1
• Prevention of RSV Infections in Bone Marrow Transplant RecipientsCompletedNCT00001903Phase 4
• Effects of Hormone Therapy on the Immune Systems of Postmenopausal Women With Chronic InfectionsCompletedNCT00001890Phase 2
• Combination Drug Treatment of Pediatric HIV InfectionCompletedNCT00001818Phase 1
• Subcutaneously Administered Interleukin-12 Therapy in HIV-Infected Patients With Disseminated Mycobacterium Avium Complex InfectionCompletedNCT00001763Phase 1
• An Open Label, Non-Comparative, Multicenter, Phase III Trial of the Efficacy, Safety and Toleration of Voriconazole in the Primary or Secondary Treatment of Invasive Fungal InfectionsCompletedNCT00001757Phase 3
• Evaluation of the Association of Polymorphisms in the Innate Immune System With the Risk for Blastomycosis Dermatitidis Infection in Patients Not Infected With HIV and Complications Associated With Blastomycosis Dermatitidis InfectionCompletedNCT00001702
• Evaluation of the Association of Polymorphisms in the Innate Immune System With the Risk for Cryptococcus Neoformans Infection in Patients Not Infected With HIV and Complications Associated With Cryptococcus Neoformans InfectionCompletedNCT00001701
• Amoxicillin for the Treatment of Pediatric Autoimmune Disorders Associated With Streptococcal InfectionsCompletedNCT00001658Phase 4
• White Blood Cell Infusions to Treat HIV InfectionCompletedNCT00001647Phase 1
• Use of Combined Antiretroviral Therapy to Determine Sites of Persistent HIV InfectionCompletedNCT00001644Phase 1
• Clinical, Laboratory and Epidemiologic Pilot Studies of Individuals at High Risk for Viral-Associated CancersCompletedNCT00001560
• Twins Study of Gene Therapy for HIV InfectionCompletedNCT00001535Phase 1
• Assessment of Attentional Functioning in Children With HIV-1 InfectionCompletedNCT00001497
• Monitoring Patients for Developing Communicable and Opportunistic Infections and for Responding to TherapyCompletedNCT00001477
• Gene Therapy for Chronic Granulomatous Diseases - Long-term Follow-upCompletedNCT00001476Phase 1
• Home Treatment of HIV-Infected Patients With Interleukin-2 With or Without a Tumor Necrosis Factor AntagonistCompletedNCT00001475Phase 2
• The Effect of Oral Candidiasis on the Speech Production, Feeding Skills, and Self-Concept of Children and Adolescents With Symptomatic HIV InfectionCompletedNCT00001448
• Phase I Study to Evaluate the Safety and Immunogenicity of HIV-1 Immunogen in Children With HIV-1 InfectionCompletedNCT00001445Phase 1
• A Phase I /II Study of the Protease Inhibitor Indinavir (MK-0639) in Children With HIV InfectionCompletedNCT00001443Phase 1
• Phase I Protocol for the Evaluation of the Safety and Immunogenicity of Vaccination With Synthetic HIV Envelope Peptides in Patients With Early Human Immunodeficiency Virus InfectionCompletedNCT00001386Phase 1
• Preventive Measures for Childhood-Onset Obsessive-Compulsive Disorder and Tic Disorders (PANDAS Subgroup)CompletedNCT00001359Phase 2
• Interleukin-2 Therapy for HIV Infection - Supplemental ProceduresCompletedNCT00001354Phase 2
• Treatment of Non-Tuberculous Mycobacterial Infections With Interferon GammaCompletedNCT00001318Phase 2
• Study of Patients With Strongyloides Stercoralis InfectionCompletedNCT00001245
• Effects of HIV on the Development and Function of Bone Marrow CellsCompletedNCT00001243
• Parasitic Infections of the Gastrointestinal TractTerminatedNCT00001162
• Assessment of Patients With Multiple Sclerosis (MS)CompletedNCT00001156
• Metabolism and Body Shape of Healthy Children and Children With Chronic InfectionsCompletedNCT00001142
• Identifying Emergency Room Patients Who Have Recently Been Infected With HIVCompletedNCT00001130
• A Study of an Adherence Plan to Help HIV-Positive Patients Take Their First Anti-HIV Medications CorrectlyCompletedNCT00001122Phase 2
• Effects on the Immune System of Anti-HIV Drugs in Patients Recently Infected With HIVCompletedNCT00001119Not applicable
• A Study to Evaluate the Effects of Anti-HIV Drugs in HIV-Positive Patients Who Also Have Hepatitis C InfectionCompletedNCT00001117
• The Effect of Acyclovir Treatment of the Herpes Simplex Virus (HSV) Infection on HIV Levels in the BloodCompletedNCT00001115Not applicable
• The Safety and Effectiveness of Human Monoclonal Antibody, F105, in the Treatment of HIVCompletedNCT00001105Phase 1
• A Study of Zidovudine in HIV-Infected Patients Who Have HemophiliaCompletedNCT00001104Phase 3
• A Phase III Study to Evaluate the Safety and Efficacy of Ganciclovir (Dihydroxypropoxymethyl Guanine [DHPG]) Treatment of Symptomatic Central Nervous System (CNS) Congenital Cytomegalovirus (CMV) Infections.CompletedNCT00001100Phase 3
• A Comparison of Nelfinavir Plus Saquinavir Plus Delavirdine or 3TC/ZDV Versus Nelfinavir Plus 3TC/ZDV in HIV-Infected PatientsWithdrawnNCT00001094Phase 2
• Outcomes of Anti-HIV Therapy During Early HIV InfectionCompletedNCT00001093
• A Study of HIV and Cytomegalovirus (CMV) in HIV-Infected PatientsCompletedNCT00001089
• The Safety and Effectiveness of Adefovir Dipivoxil in the Treatment of HIV-Infected PatientsCompletedNCT00001082Phase 3
• A Study on the Rate of Opportunistic (AIDS-Related) Infections Among HIV-Positive Children Who Have Stopped Taking Their OI Preventive MedicationsCompletedNCT00001078Not applicable
• The Safety and Effectiveness of Hydroxyurea and ddI Used Individually or Together in HIV-Infected PatientsCompletedNCT00001074Phase 1
• A Study of Amphotericin B in the Treatment of Fungal Infections of the Mouth in HIV-Infected Patients Who Have Not Had Success With FluconazoleCompletedNCT00001065Phase 2
• A Comparison of Three Drug Combinations Containing Clarithromycin in the Treatment of Mycobacterium Avium Complex (MAC) Disease in Patients With AIDSCompletedNCT00001058Phase 2
• The Effectiveness of Two Anti-HIV Treatments in HIV-Infected PatientsCompletedNCT00001057Phase 2
• The Safety and Effectiveness of Valacyclovir HCl in the Treatment of Herpes Simplex or Varicella/Zoster Infections in HIV-1 Infected ChildrenWithdrawnNCT00001054Phase 1
• A Study of Didanosine Use Alone or in Combination With Zidovudine in Infants Exposed to or Infected With HIVCompletedNCT00001049Phase 1
• Study of Four Different Treatment Approaches for Patients Who Have Mycobacterium Avium Complex Disease (MAC) Plus AIDSCompletedNCT00001047Phase 3
• Evaluation of Treatment for Mycobacterium Avium Complex (MAC) Infection in HIV-Infected PatientsCompletedNCT00001039Phase 2
• A Study of Valacyclovir Hydrochloride in the Prevention of Life-Threatening Cytomegalovirus Disease in HIV-Infected PatientsCompletedNCT00001038Phase 3
• The Safety and Effectiveness of a Type of Interleukin-2 Plus Zidovudine Plus Thymosin in HIV-Positive Patients With and Without Symptoms of InfectionCompletedNCT00001036Phase 1
• The Safety and Effectiveness of a Two-Drug Combination in the Treatment of Patients With Hepatitis C Plus Advanced HIV InfectionsCompletedNCT00001035Phase 1
• The Treatment of Tuberculosis in HIV-Infected PatientsCompletedNCT00001033Phase 3
• A Study of Dideoxycytidine Plus Zidovudine (AZT) in HIV-Infected Children Who Have Taken AZTCompletedNCT00001032Phase 2
• The Safety and Effectiveness of Clarithromycin and Rifabutin Used Alone or in Combination to Prevent Mycobacterium Avium Complex (MAC) or Disseminated MAC Disease in HIV-Infected PatientsCompletedNCT00001030Phase 3
• The Safety and Effectiveness of Rifabutin, Combined With Clarithromycin or Azithromycin, in HIV-Infected PatientsCompletedNCT00001023Not applicable
• A Study of AL721 in HIV-Infected Patients With Swollen Lymph NodesCompletedNCT00001012Phase 1
• A Study of Zidovudine Plus Acyclovir in HIV-Infected PatientsCompletedNCT00001010Phase 1
• A Study of Zidovudine Plus Interleukin-2 in HIV-Infected Patients Who Have No Symptoms of Infection But Who Have Tender Lymph NodesCompletedNCT00001005Phase 1
• A Study of Foscarnet in the Treatment of HIV Infection in Patients Who Have Taken Zidovudine for a Long TimeCompletedNCT00001002Phase 1
• A Study of Zidovudine in HIV-Infected Patients With Liver DiseaseCompletedNCT00001001Not applicable
• A Study of Atvogen in Healthy Volunteers and HIV-Infected Patients Who Have No Symptoms of InfectionCompletedNCT00001000Not applicable
• The Safety and Effectiveness of Zidovudine (AZT) in the Treatment of HIV Infection in Patients With AIDS and Advanced ARCCompletedNCT00000999Phase 1
• A Study of Dideoxycytidine in HIV-Infected PatientsCompletedNCT00000997Not applicable
• A Study of AZT Plus Ganciclovir in Patients With AIDS and Cytomegalovirus (CMV) InfectionCompletedNCT00000995Not applicable
• A Study of AZT in HIV-Infected Patients With AIDS-Related Kaposi's SarcomaCompletedNCT00000994Phase 3
• A Study of Itraconazole in Preventing the Return of Histoplasmosis, a Fungal Infection, in Patients With AIDSCompletedNCT00000992Phase 1
• A Study of Three Drugs Plus Zidovudine in the Prevention of Infections in HIV-Infected PatientsCompletedNCT00000991Phase 3
• Comparison of Foscarnet Versus Vidarabine in the Treatment of Herpes Infection in Patients With AIDS Who Have Not Had Success With AcyclovirCompletedNCT00000985Phase 3
• A Phase I Study of the Safety and Pharmacokinetics of Recombinant CD4 (rCD4) in Infants and Children Infected With or at Risk for HIV InfectionCompletedNCT00000984Phase 1
• A Study of Azidothymidine in HIV-Infected ChildrenCompletedNCT00000982Phase 2
• The Safety and Effectiveness of FIAC in the Treatment of Cytomegalovirus (CMV) in Patients With AIDSCompletedNCT00000981Phase 2
• Comparison of ddI Versus Zidovudine in HIV-Infected PatientsCompletedNCT00000979Phase 2
• A Study of Itraconazole in the Treatment and Prevention of Histoplasmosis, a Fungal Infection, in Patients With AIDSCompletedNCT00000975Phase 2
• A Study of Two Forms of Pentamidine in HIV-Infected Children Who May Have Pneumocystis Carinii PneumoniaCompletedNCT00000974Phase 1
• A Study of Pyrimethamine in the Treatment of Infection by a Certain Parasite in HIV-Positive PatientsCompletedNCT00000973Phase 1
• A Study of Foscarnet Plus Ganciclovir in the Treatment of Cytomegalovirus of the Eye in Patients With AIDS Who Have Already Been Treated With GanciclovirCompletedNCT00000970Phase 1
• A Study of Dideoxyinosine (ddI) in HIV-Infected Children Who Have Not Had Success With Zidovudine or Who Cannot Take ZidovudineCompletedNCT00000963Phase 2
• The Safety and Effectiveness of BI-RG-587 in HIV-Infected PatientsCompletedNCT00000962Phase 1
• The Safety and Effectiveness of Hyperimmune Anti-HIV Intravenous Immunoglobulin (HVIG) Plus Zidovudine in HIV-Infected InfantsTerminatedNCT00000961Phase 2
• Prophylaxis Against Tuberculosis (TB) in Patients With Human Immunodeficiency Virus (HIV) Infection and Suspected Latent Tuberculous InfectionCompletedNCT00000959Not applicable
• A Placebo-Controlled, Phase I, Pilot Clinical Trial to Evaluate the Safety and Immunogenicity of ENV 2-3, a Yeast-Derived Recombinant Envelope Protein of Human Immunodeficiency Virus-1, in Combination With MTP-PE/MF59 in Individuals With HIV Infection (Placebo Patients Receive MF59 Emulsion Only)CompletedNCT00000958Phase 1
• Two-Stage Tuberculin (PPD) Skin Testing in Individuals With Human Immunodeficiency Virus (HIV) InfectionCompletedNCT00000955Not applicable
• A Study to Evaluate the Effects of Giving Proleukin (rIL-2) to HIV-Positive Patients With CD4 Counts Greater Than 300 Cells/mm3CompletedNCT00000949Phase 3
• Effects of Giving Interleukin-2 (IL-2) Plus Anti-HIV Therapy to HIV-Positive Patients With CD4 Cell Counts of at Least 350 Cells/mm3CompletedNCT00000948Phase 2
• A Study to Evaluate the Effects of Azithromycin on MAC Disease Prevention in HIV-Positive PatientsCompletedNCT00000947Not applicable