National Institutes of Health: Atherosclerosis trials

The registry lists 108 Atherosclerosis studies with National Institutes of Health as lead sponsor. 6 are open to participants now and 5 have results posted.

Phase 1 5Phase 2 11Phase 3 9Phase 4 1No phase 85(a study in two phases counts in both)

Studies

Page 1 of 2. Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Natural History of Uncommon Dyslipidemias, Rare Lipid Disorders and Unusual Atherosclerotic ConditionsRecruitingNCT06676046
• Technical and Translational Development of Cardiovascular Magnetic Resonance (CMR) ImagingRecruitingNCT03581318
• New Heart Imaging Techniques to Evaluate Possible Heart DiseaseRecruitingNCT01399385Not applicable
• Study of the Effect of Innate on the Inflammatory Response to EndotoxinRecruitingNCT01143480
• Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular SystemRecruitingNCT01143454
• Causes and Natural History of DyslipidemiasRecruitingNCT00353782
• Pilot Study to Evaluate the Effect of Nicotinamide Riboside on Immune Activation in PsoriasisCompletedNCT04271735Not applicableResults posted
• Study to Evaluate the Effect of Nicotinamide Riboside on ImmunityCompletedNCT02812238Not applicableResults posted
• Randomized Trial of Imaging Versus Risk Factor-Based Therapy for Plaque RegressionCompletedNCT01212900Phase 4Results posted
• Rilonacept to Improve Artery Function in Patients With AtherosclerosisCompletedNCT00417417Phase 2Results posted
• Action to Control Cardiovascular Risk in Diabetes (ACCORD)CompletedNCT00000620Phase 3Results posted
• Extracellular RNAs in Relation to Cardiometabolic RiskCompletedNCT03225196
• Genes Involved in Lipid DisordersCompletedNCT02311335
• Age-Related Changes in Body CompositionTerminatedNCT01517113
• Ultrasound and Other Images of Artery BlockagesTerminatedNCT01419574
• Research on Aging Project in Iceland: Second StageCompletedNCT01322568
• Non-Invasive Assessment of Atherosclerosis in Patients With CGD and Other Disorders of the Immune SystemCompletedNCT01063309
• Human Atherosclerotic Plaque Inflammation Imaged Using PDG-PET/CTCompletedNCT00958815
• Effects of Worksite Wellness Interventions on Vascular Function, Insulin Sensitivity and High-Density Lipoprotein in Overweight or Obese WomenCompletedNCT00666172Phase 2
• Hepatitis C Treatment and AtherosclerosisCompletedNCT00659256
• Using Differences in Peripheral Blood Leukocyte Gene Expression to Determine Cardiovascular Disease RiskCompletedNCT00613158
• PET Imaging of Peripheral Benzodiazepine Receptors in Patients With Carotid AtherosclerosisCompletedNCT00547976Phase 1
• Insulin Resistance and Atherosclerosis in Women With LupusCompletedNCT00544102
• Cardiovascular Disease ScreeningTerminatedNCT00483951
• Imaging of Totally Blocked ArteriesCompletedNCT00459446Phase 1
• ClinSeq: A Large-Scale Medical Sequencing Clinical Research Pilot StudyActive, not recruitingNCT00410241
• Magnetic Resonance Angiography to Diagnose Atherosclerotic DiseaseCompletedNCT00382564
• Genetic Factors in AtherosclerosisCompletedNCT00359307
• Identification of Genes Expressed in Atherosclerotic PlaqueCompletedNCT00353730
• Observational Study of Changes in Fat Distribution and Blood Metabolites in HIV Infected AdultsStatus unknownNCT00331448
• Calcium Channel Splice Variant Expression in Cardiovascular Disease and AgingCompletedNCT00251615
• Vascular Aging: The Link That Bridges Age to Atherosclerosis (The VALIDATE Study)TerminatedNCT00246493
• EPAT: Estrogen in the Prevention of Atherosclerosis TrialCompletedNCT00115024Phase 2/3
• BVAIT: B-Vitamin Atherosclerosis Intervention TrialCompletedNCT00114400Phase 2/3
• VEAPS: Vitamin E Atherosclerosis Prevention StudyCompletedNCT00114387Phase 2/3
• Gene-Specific Responses to Exercise in Discordant TwinsCompletedNCT00083837
• Estrogen Receptor Variants, HDL, and AtherosclerosisCompletedNCT00081705
• Atherosclerosis in the Coronary and Carotid ArteriesCompletedNCT00080587
• Inflammatory Genomics in Human Carotid Artery DiseaseCompletedNCT00070668
• Genetic Determinants:Low HDL, High Triglycerides, ObesityCompletedNCT00049881
• Cardiac MR of Subclinical CVD: Impact of AgeCompletedNCT00041418
• Analysis of Sex Hormones and Lipoproteins in Young MalesCompletedNCT00037453
• Postprandial Lipemia and Endothelial Function in ACCORD- Ancillary to ACCORDCompletedNCT00037401
• Epidemiology of Cardiovascular Disease in DiabetesCompletedNCT00037297
• MRI Derived Organ & Tissue Mass Changes With Weight Loss - Ancillary to Look AHEADCompletedNCT00031200
• Technical Development of Cardiovascular Magnetic Resonance ImagingCompletedNCT00027170
• Non-Traditional Cardiovascular Risk Factors in Type 2 Diabetes Mellitus - Ancillary to VA Study of Glycemic ControlCompletedNCT00021944
• Serum Total Homocysteine and C-Reactive Protein - Ancillary to IDNTCompletedNCT00021918
• Effect of High Dose Vitamin E on Carotid AtherosclerosisCompletedNCT00010699Phase 2
• Genetic Architecture of Plasma T-PA and PAI-1CompletedNCT00007410
• Longitudinal LDL-C Studies in Black and White FamiliesCompletedNCT00007384
• Carotid Artery Thickness in HIV Infected and Uninfected AdultsCompletedNCT00007319
• Inflammation: Correlates and Prognosis in FraminghamCompletedNCT00006403
• Risk Factors for CV Disease in a Dialysis CohortCompletedNCT00006297
• Genetics of Coronary Artery Disease in Alaskan Natives (GOCADAN)CompletedNCT00006192
• Effects of Angiotensin-Converting Enzyme Inhibitor (Ramipril) Therapy on Blood Vessel InflammationCompletedNCT00005928Phase 2
• Early Atherosclerosis Change in Two Clinical TrialsCompletedNCT00005696
• Pathobiological Determinants of Atherosclerosis in Youth (PDAY)CompletedNCT00005679
• Multinational Monitoring of Trends and Determinants in Cardiovascular Disease (MONICA)CompletedNCT00005678
• Infection and Cardiovascular DiseaseCompletedNCT00005547
• Genetics of CVD Risk Factors in SamoansCompletedNCT00005528
• Strong Heart Study Analyses Obesity and LipoproteinsCompletedNCT00005510
• Multi-Ethnic Study of Atherosclerosis (MESA)Active, not recruitingNCT00005487
• The Jackson Heart Study of Cardiovascular Disease Among African AmericansActive, not recruitingNCT00005485
• Genetics of Atherosclerosis in Mexican AmericansCompletedNCT00005462
• Risk of Coronary Heart Disease in Women With Polycystic Ovary SyndromeCompletedNCT00005459
• Dietary Antioxidants and AtherosclerosisCompletedNCT00005412
• Reanalysis of CVD Risk Factors Via Likelihood MethodsCompletedNCT00005408
• Seasonal Variation of Blood Cholesterol LevelsCompletedNCT00005385
• Epidemiology of Acute Phase Protein and CHDCompletedNCT00005371
• Novel Hemostatic Cardiac Risk Factors in FraminghamCompletedNCT00005356
• Framingham Cycle V Offspring-Spouse Nutrition StudiesCompletedNCT00005347
• Homocysteine and Progression of AtherosclerosisCompletedNCT00005338
• Genetic Epidemiology of Lipoprotein-Lipid LevelsCompletedNCT00005335
• Pediatric Epidemiology of Cardiovascular Disease Risk Factors (Project Heartbeat)CompletedNCT00005264
• Mechanisms Underlying Psychosocial Associations With Ischemic Heart Disease (Kuopio)CompletedNCT00005260
• Natural History of Peripheral Arterial DiseaseCompletedNCT00005254
• Nutritional Determinants of Cardiovascular DiseaseCompletedNCT00005247
• Atherosclerosis and Omega-3 Fatty Acids in Alaskan NativesCompletedNCT00005236
• Patterns of Fatty Acids in Framingham OffspringCompletedNCT00005233
• Epidemiology of Carotid Disease in Elderly AdultsCompletedNCT00005230
• Quantitative Genetic Analysis of Lipid Research Clinic Family DataCompletedNCT00005188
• Pawtucket Heart Health ProgramCompletedNCT00005151
• Epidemiology of AtherosclerosisCompletedNCT00005147
• Insulin Resistance Atherosclerosis Study (IRAS)CompletedNCT00005135
• Strong Heart StudyCompletedNCT00005134
• Atherosclerosis Risk in Communities (ARIC)CompletedNCT00005131
• Lipid Research Clinics Population StudiesCompletedNCT00005128
• Framingham Heart StudyCompletedNCT00005121
• Effects of Hormone Replacement Therapy on Inflammation and Stiffening of Artery WallsCompletedNCT00005108Phase 2
• Aspirin Or Warfarin To Prevent StrokeTerminatedNCT00004728Phase 3
• Magnetic Resonance Imaging to Detect Blood Vessel Inflammation in Patients Undergoing Peripheral Balloon AngioplastyCompletedNCT00004549Phase 1
• Comparison of Magnetic Resonance Angiography and Standard Angiography in Diagnosing AtherosclerosisCompletedNCT00001946Phase 1
• Assessment of a B-Mode Ultrasound Technique for the Measurement of Carotid Artery Intima-Media ThicknessCompletedNCT00001904
• Effects of Hormone Therapy on the Immune Systems of Postmenopausal Women With Chronic InfectionsCompletedNCT00001890Phase 2
• Magnetic Resonance Angiography (MRA) for the Diagnosis of AtherosclerosisCompletedNCT00001841
• Racial Differences in Control of Blood Vessel Tone and Blood FlowCompletedNCT00001747
• The Role of Angiotensin Type I Receptor in the Regulation of Human Coronary Vascular FunctionCompletedNCT00001629Phase 3
• The Role of Angiotensin Type I Receptor in the Regulation of Human Peripheral Vascular FunctionCompletedNCT00001628Phase 3
• Comparison of Asymptomatic Carotid Atherosclerosis Between Frequent and Infrequent Blood DonorsCompletedNCT00001589