LEO Pharma: all 254 studies

Page 1 of 3. Open to participants first (5), then studies with results posted, then the rest; newest registration first within each.

• Real-World Evidence: Effectiveness and Safety of Chronic Hand Eczema Treatment With Delgocitinib CreamEnrolling by invitationNCT07603193
• A 52-Week Trial to Investigate the Efficacy and Safety of Delgocitinib Cream in Adult Participants With Lichen SclerosusRecruitingNCT07335588Phase 3
• A 16-week Trial to Investigate the Efficacy and Safety of Delgocitinib Cream 20 mg/g in Adult Participants With Mild to Severe Palmoplantar PustulosisRecruitingNCT07013201Phase 2
• A Study to Test Whether Spesolimab Helps People With a Skin Condition Called Pyoderma GangrenosumRecruitingNCT06624670Phase 3
• A Trial to Evaluate the Efficacy and Safety of Tralokinumab in Combination With Topical Corticosteroids in Children and Infants With Moderate-to-severe Atopic DermatitisRecruitingNCT06311682Phase 3
• A 32-week Trial to Evaluate the Efficacy and Safety of Tralokinumab in Subjects With Moderate-to-severe Atopic Hand Eczema Who Are Candidates for Systemic TherapyCompletedNCT05958407Phase 3Results posted
• A Trial to Evaluate the Efficacy and Safety of Different Doses of LEO 138559 in Adults With Moderate-to-severe Atopic DermatitisCompletedNCT05923099Phase 2Results posted
• A Study to Investigate Efficacy and Safety With LEO 90100 Compared With Daivobet® Ointment in Adult Chinese Subjects With Stable Plaque PsoriasisCompletedNCT05919082Phase 3Results posted
• A Multi-omics Disease Signature Trial in Adult Patients With Moderate to Severe ADCompletedNCT05470114Phase 2Results posted
• Efficacy and Safety of Delgocitinib Cream in Adolescents 12-17 Years of Age With Moderate to Severe Chronic Hand EczemaCompletedNCT05355818Phase 3Results posted
• A Trial to Assess the Effect of Delgocitinib Cream 20 mg/g on the Molecular Signature, Safety, and Efficacy in Adults With Frontal Fibrosing AlopeciaCompletedNCT05332366Phase 2Results posted
• The ASCEND Study: Evaluating TMB-001 in the Treatment of RXLI or ARCI IchthyosisCompletedNCT05295732Phase 3Results posted
• A 24 Week Trial to Compare the Efficacy and Safety of Delgocitinib Cream 20 mg/g Twice-daily With Alitretinoin Capsules Once-daily in Adult Participants With Severe Chronic Hand EczemaCompletedNCT05259722Phase 3Results posted
• Efficacy and Safety of Tralokinumab Administered by an Autoinjector in Adults and Adolescents With Moderate to Severe Atopic Dermatitis (INJECZTRA)CompletedNCT05194540Phase 3Results posted
• Open-label Multi-site Extension Trial in Subjects Who Completed the DELTA 1 or DELTA 2 TrialsCompletedNCT04949841Phase 3Results posted
• An Evaluation of LEO 138559 in Adults With Moderate to Severe Atopic Dermatitis.CompletedNCT04922021Phase 2Results posted
• Efficacy and Safety of Delgocitinib Cream in Adults With Moderate to Severe Chronic Hand Eczema (DELTA 2)CompletedNCT04872101Phase 3Results posted
• Efficacy and Safety of Delgocitinib Cream in Adults With Moderate to Severe Chronic Hand EczemaCompletedNCT04871711Phase 3Results posted
• Tralokinumab in Combination With Topical Corticosteroids in Japanese Subjects With Moderate-to-severe Atopic DermatitisCompletedNCT04587453Phase 3Results posted
• Efficacy and Safety of Brodalumab Compared With Guselkumab in the Treatment of Plaque Psoriasis After Inadequate Response to UstekinumabTerminatedNCT04533737Phase 4Results posted
• Efficacy and Safety of Brodalumab in Adolescents From 12 to 17 Years of Age With Moderate-to-severe Plaque PsoriasisTerminatedNCT04305327Phase 3Results posted
• A Vehicle Controlled Study to Evaluate Safety and Efficacy of Topical TMB-001 for Treatment of Congenital IchthyosisCompletedNCT04154293Phase 2Results posted
• Efficacy and Safety of Delgocitinib Cream in Discoid Lupus Erythematosus.TerminatedNCT03958955Phase 2Results posted
• Efficacy and Safety of LEO 90100 Foam in Japanese Subjects With Psoriasis VulgarisCompletedNCT03806790Phase 3Results posted
• Tralokinumab in Combination With Topical Corticosteroids in Subjects With Severe Atopic Dermatitis - ECZTRA 7CompletedNCT03761537Phase 3Results posted
• Dose-ranging Trial to Evaluate Delgocitinib Cream 1, 3, 8, and 20 mg/g Compared to Delgocitinib Cream Vehicle Over an 8-week Treatment Period in Adult Subjects With Atopic Dermatitis.CompletedNCT03725722Phase 2Results posted
• Phase 2b Dose-ranging Trial to Evaluate Delgocitinib Cream 1, 3, 8, and 20 mg/g Compared to Delgocitinib Cream Vehicle Over a 16-week Treatment Period in Adult Subjects With Chronic Hand EczemaCompletedNCT03683719Phase 2Results posted
• Long-term Extension Trial in Subjects With Atopic Dermatitis Who Participated in Previous Tralokinumab Trials - ECZTENDCompletedNCT03587805Phase 3Results posted
• Vaccine Responses in Tralokinumab-Treated Atopic Dermatitis - ECZTRA 5 (ECZema TRAlokinumab Trial No. 5)CompletedNCT03562377Phase 2Results posted
• Tralokinumab Monotherapy for Adolescent Subjects With Moderate to Severe Atopic Dermatitis - ECZTRA 6 (ECZema TRAlokinumab Trial no. 6).CompletedNCT03526861Phase 3Results posted
• Tralokinumab in Combination With Topical Corticosteroids for Moderate to Severe Atopic Dermatitis - ECZTRA 3CompletedNCT03363854Phase 3Results posted
• A Trial Comparing the Efficacy of Subcutaneous Injections of Brodalumab to Oral Administrations of Fumaric Acid Esters in Adults With Moderate to Severe Plaque PsoriasisCompletedNCT03331835Phase 4Results posted
• Tralokinumab Monotherapy for Moderate to Severe Atopic Dermatitis - ECZTRA 2 (ECZema TRAlokinumab Trial no. 2)CompletedNCT03160885Phase 3Results posted
• Tralokinumab Monotherapy for Moderate to Severe Atopic Dermatitis - ECZTRA 1 (ECZema TRAlokinumab Trial no. 1)CompletedNCT03131648Phase 3Results posted
• A Trial to Compare the Incidence of Squamous Cell Carcinoma (SCC) and Other Skin Neoplasia on Skin Areas Treated With Ingenol Disoxate Gel or Vehicle Gel for Actinic Keratosis on Face and Chest or ScalpTerminatedNCT03115476Phase 3Results posted
• LEO 90100 Twice Weekly Maintenance Regimen for Psoriasis VulgarisCompletedNCT02899962Phase 3Results posted
• LEO 80185 Gel (Calcipotriol Hydrate Plus Betamethasone Dipropionate) in Japanese Subjects With PsoriasisCompletedNCT02668692Phase 3Results posted
• Explorative Trial Evaluating the Efficacy and Tolerability of LEO43204 in Moderate to Severe AcneCompletedNCT02575950Phase 2Results posted
• LEO 124249 Ointment in the Treatment of Alopecia AreataCompletedNCT02561585Phase 2Results posted
• Efficacy and Safety of LEO 43204 in Field Treatment of Actinic Keratosis on Balding Scalp Including 12-month Follow-upCompletedNCT02549352Phase 3Results posted
• Efficacy and Safety of LEO 43204 in the Field Treatment of Actinic Keratosis on Face or Chest including12-month Follow-upCompletedNCT02549339Phase 3Results posted
• Efficacy and Safety of LEO 43204 in Field Treatment of Actinic Keratosis on Balding Scalp Including 12-month Follow-upCompletedNCT02547363Phase 3Results posted
• Efficacy and Safety of LEO 43204 in Field Treatment of Actinic Keratosis on Face or Chest Including 12-month Follow-upCompletedNCT02547233Phase 3Results posted
• A Psoriasis Plaque Test Trial With LEO 90100 Compared to Betesil® in Patients With Psoriasis VulgarisCompletedNCT02518048Phase 2Results posted
• Safety and Efficacy of Once Daily Topical Treatment With LEO 90100 Aerosol Foam in Adolescent Subjects With Plaque PsoriasisCompletedNCT02387853Phase 2Results posted
• Efficacy and Safety of Ingenol Mebutate Gel for Actinic Keratosis Applied on Large Area on Face, Scalp or ChestCompletedNCT02361216Phase 3Results posted
• Patient Insights Following Use of LEO 90100 Aerosol Foam and Daivobet® Gel in Subjects With Psoriasis VulgarisCompletedNCT02310646Phase 3Results posted
• Safety of LEO 43204 for Actinic Keratosis Applied on Face/Chest, Scalp and Trunk/Extremities, RespectivelyCompletedNCT02305888Phase 2Results posted
• LEO 90100 Aerosol Foam Compared to Calcipotriol Plus Betamethasone Dipropionate Gel in Subjects With Psoriasis VulgarisCompletedNCT02132936Phase 3Results posted
• Safety and Efficacy of Escalating Doses of LEO 43204 Applied Once Daily for Two Consecutive Days on Approximately 250 cm2 on Trunk and Extremities in Subjects With Actinic KeratosisCompletedNCT02120456Phase 1/2Results posted
• Safety and Efficacy of Doses of LEO 43204 Once Daily for Two Consecutive Days on Full Balding Scalp in Subjects With Actinic KeratosisCompletedNCT02100813Phase 1/2Results posted
• An International, Multi-centre, Prospective, Non-controlled, Open, Single-group, 8-week Trial in Adolescent SubjectsCompletedNCT02038569Phase 2Results posted
• Efficacy and Safety of Ingenol Mebutate Gel 0.06% When Applied Once Daily for 2, 3 or 4 Consecutive Days to a Treatment Area of Approximately 250 cm2 on Trunk and Extremities in Subjects With Actinic KeratosisCompletedNCT01998984Phase 2Results posted
• Topical Aprepitant in Prurigo PatientsCompletedNCT01963793Phase 2Results posted
• Risk of Squamous Cell Carcinoma on Skin Areas Treated With Ingenol Mebutate Gel, 0.015% and Imiquimod Cream, 5%CompletedNCT01926496Phase 4Results posted
• A Study of Increasing Strengths, Safety and Efficacy of Two Formulas of LEO 43204 on the Face or the Chest in Patients With Actinic KeratosisCompletedNCT01922050Phase 1/2Results posted
• LEO 90100 Compared to Vehicle in Subjects With Psoriasis VulgarisCompletedNCT01866163Phase 3Results posted
• Safety and Efficacy of Ingenol Mebutate Once Daily for 2 or 3 Consecutive Days in Subjects With Actinic KeratosisCompletedNCT01820260Phase 1/2Results posted
• A Simultaneous Treatment Regimen Compared to a Sequential Treatment Regimen With Ingenol Mebutate Gel 0.015% and 0.05% of Two Areas With Actinic Keratosis on Face/Scalp and Trunk/ExtremitiesCompletedNCT01787383Phase 3Results posted
• The Pharmacokinetics of LEO 90105 (Calcipotriol Hydrate Plus Betamethasone Dipropionate) in Japanese Subjects With Extensive Psoriasis VulgarisCompletedNCT01768013Phase 1/2Results posted
• Non-interventional Study of Long-term Treatment of Psoriasis With Calcipotriol Plus Betamethasone in Gel FormulationCompletedNCT01707368Results posted
• A Short-contact Plaque Test Study With Daivobet® Gel in Psoriasis VulgarisCompletedNCT01607853Phase 2Results posted
• Effect of LEO 90100 on the HPA Axis and Calcium Metabolism in Subjects With Extensive Psoriasis VulgarisExtensive Psoriasis VulgarisCompletedNCT01600222Phase 2Results posted
• Ingenol Mebutate Gel, 0.015% Repeat Use for Multiple Actinic Keratoses on Face and ScalpCompletedNCT01600014Phase 3Results posted
• A Plaque Test Study With LEO 35299 in Psoriasis VulgarisCompletedNCT01580488Phase 1Results posted
• Safety and Efficacy of Azelaic Acid Foam, 15 % in Papulopustular RosaceaCompletedNCT01555463Phase 3Results posted
• A Sequential Treatment Regimen of Cryotherapy and Picato® for the Treatment of Actinic Keratosis on the Face and ScalpCompletedNCT01541553Phase 3Results posted
• LEO 90100 in the Treatment of Psoriasis VulgarisCompletedNCT01536938Phase 2Results posted
• LEO 90100 Compared With Calcipotriol Plus Betamethasone Dipropionate Ointment, LEO 90100 Vehicle and Ointment Vehicle in Subjects With Psoriasis VulgarisCompletedNCT01536886Phase 2Results posted
• Efficacy and the Tolerability of the Sequential Application of Two Marketed Products in Patients With Acne VulgarisCompletedNCT01461655Phase 2Results posted
• PEP005 Gel - Biological Effects in Actinic Keratosis Assessed by Reflectance Confocal MicroscopyCompletedNCT01449513Phase 1Results posted
• LEO 90105 Ointment in Japanese Subjects With PsoriasisCompletedNCT01422434Phase 3Results posted
• A Psoriasis Plaque Test Study With LEO 90100 Cutaneous Spray, Ointment, in Psoriasis VulgarisCompletedNCT01347255Phase 2Results posted
• Efficacy and Safety of Xamiol® Gel Compared to Calcipotriol Scalp Solution in Patients With Scalp PsoriasisCompletedNCT01195831Phase 3Results posted
• LEO 80185 in the Treatment of Psoriasis Vulgaris on the Non-scalp Regions of the Body (Trunk and/or Limbs)CompletedNCT01188928Phase 3Results posted
• Safety and Efficacy of LEO 80185 Gel in Adolescent Subjects (Aged 12 to 17) With Scalp PsoriasisCompletedNCT01120223Phase 2Results posted
• A Proof of Concept Study Comparing Three Doses of an Oral Solution of LEO 22811 With a Placebo Oral Solution for the Treatment of Psoriasis VulgarisCompletedNCT01116895Phase 2Results posted
• Safety and Efficacy of LEO 80185 Topical Suspension in Adolescent Subjects (Aged 12 to 17) With Scalp PsoriasisCompletedNCT01083758Phase 2Results posted
• LEO 29102 Cream in the Treatment of Atopic DermatitisCompletedNCT01037881Phase 2Results posted
• Safety and Efficacy of Azelaic Acid Foam, 15% in Papulopustular RosaceaCompletedNCT01025635Phase 2Results posted
• A Study Comparing LEO 80190 Ointment With Hydrocortisone Ointment, Both Applied Once Daily in the Treatment of Psoriasis Vulgaris on the Face and Intertriginous AreasCompletedNCT01007591Phase 3Results posted
• Fucidin® Cream in the Treatment of ImpetigoTerminatedNCT00986856Phase 4Results posted
• A Multicenter Study to Evaluate the Efficacy and Safety of PEP005 (Ingenol Mebutate) Gel When Used to Treat Actinic Keratoses (AKs) on the Non Head LocationsCompletedNCT00942604Phase 3Results posted
• A Multi-center Study to Evaluate the Efficacy and Safety of PEP005 (Ingenol Mebutate) Gel, When Used to Treat Actinic Keratoses on the Head (Face or Scalp)CompletedNCT00916006Phase 3Results posted
• A Multi-Center Study to Evaluate the Efficacy and Safety of PEP005 (Ingenol Mebutate) Gel, When Used to Treat Actinic Keratoses on the Head (Face or Scalp)CompletedNCT00915551Phase 3Results posted
• A Psoriasis Plaque Test With LEO 29102 Cream and Its Combination ProductsCompletedNCT00875277Phase 2Results posted
• Efficacy of Topical Azelaic Acid 15% Gel Plus Anti-inflammatory Dose Doxycycline or Metronidazole Gel 1% Plus Anti-inflammatory Dose Doxycycline in Moderate Papulopustular RosaceaCompletedNCT00855595Phase 4Results posted
• A Study to Evaluate the Pharmacokinetics of PEP005 (Ingenol Mebutate) Gel, 0.05%, When Applied in a Maximal Use Setting to the Dorsal Aspect of the Forearm in Patients With Actinic KeratosisCompletedNCT00852137Phase 2Results posted
• A Plaque Test Comparing the Anti-psoriatic Effect of Marketed Products for Topical Use for Psoriasis VulgarisCompletedNCT00845481Phase 2Results posted
• Safety and Efficacy of TACLONEX Ointment in Adolescent Patients (Aged 12 to 17 Years) With Psoriasis VulgarisCompletedNCT00817219Phase 2Results posted
• Efficacy and Safety of LEO 19123 Cream in the Treatment of Psoriasis VulgarisCompletedNCT00764751Phase 2Results posted
• The Pharmacokinetics of 2% TD1414 Cream in Adults With Secondarily Infected Traumatic Lesions (SITL) or ImpetigoCompletedNCT00758862Phase 2Results posted
• A Multicenter Study to Evaluate the Efficacy and Safety of PEP005 (Ingenol Mebutate) Gel When Used to Treat Actinic Keratoses (AKs) on the Non Head LocationsCompletedNCT00742391Phase 3Results posted
• Effect of Calcipotriol Plus Hydrocortisone Ointment on the Adrenal Hormone Balance and Calcium Metabolism in Patients With Psoriasis Vulgaris on the Face and Skin FoldsCompletedNCT00704262Phase 2Results posted
• A Multicenter Study to Evaluate the Safety and Efficacy of PEP005 Topical Gel When Used to Treat Actinic Keratoses on the Head (Face or Scalp)CompletedNCT00700063Phase 2Results posted
• Efficacy and Safety of Calcipotriol Plus Hydrocortisone Ointment in Psoriasis Vulgaris on the Face and Skin FoldsCompletedNCT00691002Phase 3Results posted
• Efficacy and Safety of Calcipotriol Plus Betamethasone Dipropionate Gel Compared With Tacalcitol Ointment and the Gel Vehicle Alone in Patients With Psoriasis VulgarisCompletedNCT00670241Phase 3Results posted
• Efficacy and Safety of Calcipotriol Plus Hydrocortisone Ointment Compared With Tacalcitol Ointment in Patients With Psoriasis on the Face and Skin FoldsCompletedNCT00640822Phase 3Results posted
• Efficacy, Safety, and Tolerability of TD1414 2% Cream in Impetigo and Secondarily Infected Traumatic Lesions (SITL)CompletedNCT00626795Phase 2Results posted
• Exploration of Safety and Efficacy of AzA 15% Foam Twice a Day in RosaceaCompletedNCT00617903Phase 2Results posted

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