LEO Pharma: all 254 studies

Page 2 of 3. Open to participants first (5), then studies with results posted, then the rest; newest registration first within each.

• Recombinant Human Antithrombin (ATryn®) in the Treatment of Patients With DIC Associated With Severe SepsisTerminatedNCT00506519Phase 2Results posted
• Innohep® in Elderly Patients With Impaired Renal Function Treated for Acute Deep Vein ThrombosisCompletedNCT00277394Phase 4Results posted
• A Study to Evaluate Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Single Dose of LEO 158968CompletedNCT06444867Phase 1
• A Study to Test Whether Spesolimab Helps People With Generalized Pustular Psoriasis (GPP) Who Need Treatment for Repeated FlaresActive, not recruitingNCT06013969Phase 4
• A Trial to Evaluate Efficacy, Safety, and Pharmacokinetics of Delgocitinib Cream in Chinese Adults and Adolescents With Moderate to Severe Chronic Hand EczemaCompletedNCT06004050Phase 3
• Investigating the Safety of LEO 158968 in Healthy VolunteersCompletedNCT05682352Phase 1
• Pharmacokinetics of Delgocitinib 20 mg/g Cream in Subjects With Chronic Hand EczemaCompletedNCT05486117Phase 1
• Tralokinumab Monotherapy for Children With Moderate-to-severe Atopic Dermatitis - TRAPEDS 1 (TRAlokinumab PEDiatric Trial no. 1)CompletedNCT05388760Phase 2
• A Trial to Evaluate Pharmacokinetics, Immunogenicity, Safety, and Tolerability of LEO 138559 in Healthy Japanese SubjectsCompletedNCT05099133Phase 1
• A Trial to Evaluate the Effect of Delgocitinib on the Heart Rhythm of Healthy PeopleCompletedNCT05050279Early Phase 1
• A Single and Multiple Ascending-dose Trial of LEO 153339 in Healthy AdultsCompletedNCT04883333Phase 1
• Clinical Trial to Evaluate UV-light-induced Allergic Skin Reactions After Application of Delgocitinib CreamCompletedNCT04807751Phase 1
• A Trial to Compare the Pharmacokinetics of Tralokinumab in Healthy SubjectsCompletedNCT04674826Phase 1
• Clinical Trial to Evaluate Light-induced Skin Reactions After Application of Delgocitinib CreamCompletedNCT04361136Phase 1
• Adjusted Brodalumab Dose Compared With Standard Brodalumab Dose in Subjects With Moderate-to-severe Plaque Psoriasis and ≥120 kg Body WeightCompletedNCT04306315Phase 4
• TreatMent of ActInic KerAtosis Lesions : pharmacoepiDemiological Study of the Impact in Real Life of ingenOl Mebutate Gel (Picato®) on Patients SatisfactionCompletedNCT04202445
• Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics After Single and Multiple Doses of LEO 142397 in Healthy People, Including JapaneseWithdrawnNCT03995550Phase 1
• Clinical Trial to Assess Safety, Tolerability and the Pharmacodynamics Effect of Calcipotriol/Betamethasone Dipropionate in a New Administration Form in Subjects With Chronic Plaque Psoriasis.CompletedNCT03898583Phase 1
• Effisayil™ ON: A Study to Test Long-term Treatment With Spesolimab in People With Generalized Pustular Psoriasis Who Took Part in a Previous StudyActive, not recruitingNCT03886246Phase 2
• Delgocitinib Cream for the Treatment of Moderate to Severe Atopic Dermatitis During 8 Weeks in Adults, Adolescents, and ChildrenCompletedNCT03826901Phase 1
• A Trial to Investigate the Safety, Tolerability, and Drug Levels in Blood After Single and Multiple Doses of LEO 32731 in Healthy PeopleCompletedNCT03812198Phase 1
• A Study to Learn More About the Relationship Between the Development of a Gap in the Upper Lip (Cleft Lip) or in the Roof of the Mouth (Cleft Palate) in Newborns and the Use of Glucocorticoids by the Mother During Pregnancy: a Meta-analysisCompletedNCT03788863
• Investigation of Flare and Remission in Subjects With Atopic DermatitisWithdrawnNCT03710044Phase 4
• Tacrolimus Blood Levels After Topical Application of Tacrolimus on Healthy SkinCompletedNCT03673527Phase 1
• Clinical Trial to Assess Safety, Tolerability and the Pharmacodynamic Effect of Different Concentrations of a New Anti-inflammatory Substance in Subjects With Chronic Plaque PsoriasisCompletedNCT03669757Phase 1
• Drug-drug Interaction Trial With Tralokinumab in Moderate to Severe Atopic Dermatitis - ECZTRA 4CompletedNCT03556592Phase 1
• Safety and Tolerability of LEO 138559 in Healthy Subjects and Subjects With Atopic DermatitisCompletedNCT03514511Phase 1
• Dermatopharmacokinetic Trial of LEO 90100 FoamCompletedNCT03476746Phase 1
• Skin Irritation of LEO 90100 Foam (Calcipotriol Hydrate Plus Betamethasone Dipropionate) in Healthy Japanese SubjectsCompletedNCT03442244Phase 1
• Body PSOriasis: Long-term Relapse CONTROLCompletedNCT03402828
• Efficacy and Safety of Fucicort® Lipid Cream Compared to Combination Treatment With Fucidin® Cream Followed by Betamethasone (Lianbang Beisong®) Cream and Fucicort® Lipid Cream Vehicle in Clinically Infected Atopic Dermatitis/EczemaTerminatedNCT03395132Phase 3
• Efficacy of Twice Daily Application of LEO 124249 Ointment 30 mg/g for 12 Weeks on Eyebrow Alopecia Areata.TerminatedNCT03325296Phase 2
• Multiple Dose Study With Incremental Dosing to Evaluate the Safety, Tolerability, and Pharmacokinetics of Oral Doses of LEO 32731 in Healthy Male Japanese Subjects.CompletedNCT03231124Phase 1
• A Study of Patient Concerns and Treatment Satisfaction in Patients Being Treated With Finacea Foam for RosaceaCompletedNCT03193372
• Skin IaM: An Exploratory Clinical Trial to Evaluate Changes in Skin Appearance, Colour, and/or Texture Following the Induction of a Local Inflammatory Skin ResponseCompletedNCT03192280Not applicable
• Open-label, Single Center, Non-randomized, Fixed Sequence Phase 1 Drug-drug Interaction Study With LEO 32731 and MidazolamCompletedNCT03126578Phase 1
• Non Interventional Study of the Validation of the Ottawa Score in Cancer Patients With Venous Thromboembolism (VTE)CompletedNCT03099031
• Vasoconstriction Trial With LEO 90100 Aerosol FoamCompletedNCT02973776Phase 1
• PSOREAL - Managing PSOriasis in the REAL WorldCompletedNCT02935582
• LEO 32731 for the Treatment of Moderate to Severe Psoriasis VulgarisCompletedNCT02888236Phase 2
• Efficacy and Tolerability of Enstilar® in Daily PracticeCompletedNCT02881346
• Real-life Evaluation of the Daivobet® Gel ApplicatorCompletedNCT02856542
• A Phase I Study With LEO 32731 and Midazolam in Healthy Male SubjectsTerminatedNCT02753218Phase 1
• Trial Twice Daily Application of LEO 124249 Ointment 30 mg/g in Treatment of Mild to Moderate Inverse PsoriasisCompletedNCT02695940Phase 2
• Proof of Concept, Twice Daily Applications of LEO 124249 Ointment in the Treatment of Chronic Hand EczemaCompletedNCT02664805Phase 2
• A Clinical Study to Evaluate the Sensitizing Potential of LEO 43204 GelCompletedNCT02650505Phase 1
• Xamiol®Gel in BODY Psoriasis: A One-year Non-interventional StudyCompletedNCT02636101
• An Observational Study Investigating the Treatment Satisfaction of Atopic Dermatitis Patients Who Have Switched to Ointment (W/O Emulsion) Formulation of Very Strong Class Topical CorticosteroidsCompletedNCT02627989
• Dermatopharmacokinetic Trial of LEO 80185 GelCompletedNCT02605057Phase 1
• Preferences & Treatment Satisfaction Drivers in Rosacea PatientsCompletedNCT02602470
• Biological Effects of LEO 43204 in Actinic KeratosisCompletedNCT02600598Phase 1
• The Use of Picato® (Ingenol Mebutate) to Treat Actinic Keratosis in Standard Clinical PracticeCompletedNCT02594436
• An Exploratory Trial Investigating the Neurogenic Component in Psoriasis Vulgaris by Use of Botulinum Toxin ACompletedNCT02577185Phase 1
• Long-term Treatment of Scalp Psoriasis With Xamiol® Gel in a Large Adult Chinese PopulationCompletedNCT02533973Phase 4
• LEO 32731 - A Phase I Study in Healthy SubjectsCompletedNCT02514694Phase 1
• An Explorative Trial Evaluating the Effect of LEO 32731 Cream in Adults With Mild to Moderate Atopic Dermatitis (AD)CompletedNCT02496546Phase 1
• Pharmacokinetics of LEO 43204 Gel in Actinic Keratosis Administered Under Maximal Use ConditionsCompletedNCT02424305Phase 1
• PMS to Evaluate the Safety and Efficacy of Picato® GelCompletedNCT02421471
• A Psoriasis Plaque Test Trial With LP0113 Spray in Patients With Psoriasis Vulgaris (LP0113-1123)CompletedNCT02416258Phase 2
• Efficacy and Safety of Ingenol Mebutate Gel 0.015% Compared to Diclofenac Sodium Gel 3% in Subjects With Actinic Keratoses on the Face or ScalpCompletedNCT02406014Phase 4
• A Clinical Trial to Assess the Potential of LEO 130852A Gel to Reduce Steroid Induced Skin Atrophy on Healthy SkinCompletedNCT02392130Phase 1
• Skin Irritation Test of LEO 80185 Gel in Healthy Japanese SubjectsCompletedNCT02379793Phase 1
• Safety and Efficacy of Repeat Use of Picato® 0.05% in the Treatment of Anogenital WartsCompletedNCT02377999Phase 2
• A Clinical Trial to Compare Topical Agents in Adults With Mild to Moderate Atopic Dermatitis (AD)CompletedNCT02376049Phase 1
• The Real Life Topical Field Treatment of Actinic Keratosis StudyCompletedNCT02362152
• A Single-Centre Clinical Trial to Assess Steroid Induced Skin Atrophy on Healthy SkinCompletedNCT02355639Phase 1
• Effect of LEO 39652 Cream in Adults With Mild to Moderate Atopic Dermatitis (AD)CompletedNCT02219633Phase 1
• LP0058-1005 - A Open-Label, Four-Way Crossover and Food-Effect Study of LEO 32731 in Healthy SubjectsCompletedNCT02126371Phase 1
• Pharmacokinetics of Ingenol Mebutate Gel in Actinic Keratosis Under Maximum Use ConditionsCompletedNCT02124239Phase 1
• A Multi-Centre Clinical Trial to Evaluate a Left-Right Design in Adults With Mild to Moderate Atopic DermatitisCompletedNCT02103725Phase 1
• Assessment of Treatment Success and Quality of Life in Patients With Actinic Keratoses Under Therapy With Ingenol Mebutate in a Period of 8 WeeksCompletedNCT02090465
• An Observational Study to Assess Patient Satisfaction and Control of Psoriasis With Calcipotriene/Betamethasone Dipropionate (Taclonex®) Topical Suspension, and Effect on Quality of LifeCompletedNCT01982552
• A Vasoconstriction Study With LEO 90100CompletedNCT01946386Phase 1
• Combined Cumulative Irritation Potential and Repeat Insult Patch Test of LEO 90100CompletedNCT01935869Phase 1
• Histological Confirmation of Clinical Clearance of Actinic Keratoses Following Treatment With Ingenol Mebutate Gel, 0.05%CompletedNCT01892137Phase 1
• Safety, Tolerability and Pharmacokinetics in AD Subjects and Healthy Subjects of Cutaneous Application of LEO 39652 CreamCompletedNCT01850849Phase 1
• An Exploratory Psoriasis Plaque Test Study With Different Dose Combinations of Calcipotriol Plus Betamethasone Dipropionate in the Daivobet® Gel Vehicle in Psoriasis VulgarisCompletedNCT01837576Phase 1
• Safety and Dose Finding Study of New Vehicle Formulations Containing Ingenol Mebutate to Treat Actinic Keratosis on the ForearmCompletedNCT01803477Phase 1/2
• Prescription and Utilization of Low Molecular Weight Heparin in Usual Medical Practice for the Curative Treatment of Venous Thromboembolism in Patients With CancerCompletedNCT01803022
• Cromoglicate in PsoriasisCompletedNCT01722812Phase 2
• Safety and Tolerability of Different Concentrations of an Ingenol Derivative Field Therapy in the Treatment of Actinic KeratosisCompletedNCT01703078Phase 1
• Cromoglicate in MastocytosisTerminatedNCT01701843Phase 2
• Study on Thrombosis Therapy in German Cancer PatientsCompletedNCT01559883
• An Exploratory Psoriasis Plaque Test Study With LEO 29102 Plus Calcipotriol, Ointment, in Psoriasis VulgarisCompletedNCT01466478Phase 1
• Safety, Tolerability and Pharmacokinetics of LEO 29102 Cream in Atopic Dermatitis.TerminatedNCT01447758Phase 1
• Human Repeated Insult Patch Test (HRIPT) of Azelaic Acid Pre Foam FormulationCompletedNCT01430533Phase 1
• 21 Day Irritancy Test of Azelaic Acid Pre-foam FormulationCompletedNCT01430312Phase 1
• Safety, Tolerability and Pharmacokinetic Study in Healthy Subjects by Dermal Application of a LEO 29102CompletedNCT01423656Phase 1
• PEP005 Gel - Biological Effects in Actinic Keratosis Assessed by HistologyCompletedNCT01387711Phase 1
• PEP005 Gel - Evaluation of the Safety and Efficacy of Ingenol Mebutate Gel on a Superficial Basal Cell Carcinoma on the Trunk or ExtremitiesCompletedNCT01325688Phase 2
• Efficacy, Tolerability and Handling of Daivobet® Gel in Patients With Psoriasis VulgarisCompletedNCT01320774
• LEO 32731 - A Study in Healthy Male SubjectsCompletedNCT01310049Phase 1
• PEP005 Gel - Evaluation of Local Tolerability After Exposure to Ingenol Mebutate Gel Followed by Hand Washing in Healthy SubjectsCompletedNCT01302925Phase 1
• A Psoriasis Plaque Test on LEO 27989 Ointment and Calcipotriol Plus LEO 27989 Ointment in Patients With Psoriasis VulgarisCompletedNCT01297166Phase 1
• A Study Evaluating the Safety of LEO 90105 and Its Vehicle, After Multiple Administration on Intact Skin of Healthy Japanese Male SubjectsCompletedNCT01293383Phase 1
• A Study Evaluating Skin Irritation, Phototoxicity and Safety After Administration of LEO 90105 on Intact Skin of Healthy Japanese Male SubjectsCompletedNCT01293357Phase 1
• Preventive Treatment of VETD in Patients With Multiple Myeloma Receiving Chemotherapy With Thalidomide or Lenalinomide.CompletedNCT01268774
• Safety and Pharmacokinetics of Azelaic Acid Foam, 15% in Papulopustular RosaceaCompletedNCT01257919Phase 1
• Effect of LEO 80185 Gel on the HPA Axis and Calcium Metabolism in Subjects With Extensive Psoriasis VulgarisCompletedNCT01229098Phase 2
• Study to Evaluate the Safety and Efficacy of PEP005 (Ingenol Mebutate) Gel, 0.015%, in Patients With Photo-damaged SkinCompletedNCT01214577Phase 2

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