Institute of Cancer Research, United Kingdom: all 113 studies

Page 1 of 2. Open to participants first (27), then studies with results posted, then the rest; newest registration first within each.

• Understanding the Genetic and Biological Factors That Influence Cancer Treatment Response and Resistance in Patients With Advanced Solid Tumours Through Sample AnalysisRecruitingNCT07737509
• Investigating the Combination of Bexmarilimab and Nivolumab in Solid Tumours, Melanoma and NSCLCRecruitingNCT07718243Phase 1/2
• The BALANCE Study: BlAck and Mixed Men's Lived Experience With Prostate cANCEr-Diversity in Prostate Cancer PROMS StudyNot yet recruitingNCT07529418
• 5G-PEARL: Paxalisib in Malignant Brain TumoursRecruitingNCT07391215Phase 1/2
• The eValuation of Sources of vIBRAtioN for Vibrational Shear Wave elasTographyNot yet recruitingNCT07098819
• Investigating SX-682 in Combination With Apalutamide in Metastatic Castration-resistant Prostate CancerRecruitingNCT07002320Phase 1/2
• Investigating Idetrexed and Olaparib in Patients With Ovarian CancerRecruitingNCT06976892Phase 1
• The COherence of Scatter Identification and Exclusion Algorithm StudyRecruitingNCT06975579
• The i4i PRODICT® Study: Evaluation of the i4i PRODICT® Test in Different Ethnic Groups (The i4i PRODICT® Study).RecruitingNCT06636526
• 5G-RUBY: Avutometinib and Defactinib in Malignant Brain TumoursRecruitingNCT06630260Phase 1/2
• Microbiome Molecular CharaterisationRecruitingNCT06423976
• Deployment and Clinical Evaluation of an AI-powered Digital Oncology Biomarker Tool to guidE Treatment in TNBCNot yet recruitingNCT06396754
• Combination Study of Antibiotics With Enzalutamide (PROMIZE)RecruitingNCT06126731Phase 1/2
• SBRT Alone or Followed by Niraparib for Oligometastases or Oligoprogression in Ovarian Cancer Following PARPi TherapyRecruitingNCT05990192Phase 2
• Myeloma Novel Drug Discovery Ver 1.2RecruitingNCT05968417
• The Active Surveillance StudyRecruitingNCT05810467
• A Trial of 5 Fraction Prostate SBRT Versus 5 Fraction Prostate and Pelvic Nodal SBRTRecruitingNCT05613023Phase 3
• The GENPET Study - An Imaging Study of FCH-PET-CT in Men With Prostate Cancer and a DNA Repair Gene Mutation.RecruitingNCT05097274
• Precision Medicine in the Prostate Cancer Care PathwayRecruitingNCT04763317
• Hypofractionated Expedited Radiotherapy for Men With localisEd proState CancerRecruitingNCT04595019Not applicable
• PHOENIX DDR/Anti-PD-L1 Trial: A Pre-surgical Window of Opportunity and Post-surgical Adjuvant Biomarker Study of DNA Damage Response Inhibition With or Without Anti-PD-L1 Immunotherapy in Patients With Neoadjuvant Treatment Resistant Residual Triple Negative Breast CancerRecruitingNCT03740893Phase 2
• Prospective Evaluation of Radiotherapy Using Magnetic Resonance Image Guided TreatmentRecruitingNCT03727698Not applicable
• Trial of Pembrolizumab in Metastatic Castration Resistant Prostate CancerRecruitingNCT03506997Phase 2
• PUMA (Paediatric Osseous Marrow Assessment)RecruitingNCT03466944
• PRIMER: Development of Daily Online Magnetic Resonance Imaging for Magnetic Resonance Image Guided RadiotherapyRecruitingNCT02973828
• Analysing Outcomes After Prostate Cancer Diagnosis and Treatment in Carriers of Rare Germline MutationsRecruitingNCT02705846
• The PROFILE Study: Germline Genetic Profiling: Correlation With Targeted Prostate Cancer Screening and TreatmentRecruitingNCT02543905
• Study of Weekly Radiotherapy for Bladder CancerCompletedNCT01810757Not applicableResults posted
• A Phase II Study of Axitinib in Patients With Metastatic Renal Cell Cancer Unsuitable for NephrectomyCompletedNCT01693822Phase 2Results posted
• Study of Faslodex +/- Concomitant Arimidex v Exemestane Following Progression on Non-steroidal Aromatase InhibitorsCompletedNCT00253422Phase 3Results posted
• 5G-EMERALD: Amivantamab in Malignant Brain TumoursActive, not recruitingNCT06632236Phase 1
• POTENT - Tepotinib in Combination With Pembrolizumab in NSCLCActive, not recruitingNCT05782361Phase 1
• ASTEROID: A Trial of ASTX660 in Combination With PembrolizumabActive, not recruitingNCT05082259Phase 1
• Digital Delivery of Information About Genetic Testing for Breast CancerCompletedNCT04842799Not applicable
• Exploring the Mechanisms and Dynamics of Clonal Evolution Leading to Recurrence in Prostate CancerStatus unknownNCT04686188
• CORONADO (Circulating tumOur pROtein quaNtification cApillary blooD cOvid-19)Status unknownNCT04659252
• PreOperative Endocrine Therapy for Individualised Care With AbemaciclibActive, not recruitingNCT04584853Phase 3
• Abiraterone Acetate in Combination With TildrakizumabTerminatedNCT04458311Phase 1/2
• ATr Inhibitor in Combination With Olaparib/Durvalumab (MEDI4736) in Gynaecological Cancers With ARId1A Loss or no LossActive, not recruitingNCT04065269Phase 2
• Exploring the Link Between Cancer Genetics and PPSPStatus unknownNCT04007861
• KORTUC Phase II - Intra-tumoural Radiation Sensitizer in Patients With Locally Advanced/Recurrent Breast CancerActive, not recruitingNCT03946202Phase 2
• Molecular Stratification Profiling Protocol in Metastatic Castration Resistant Prostate Cancer (mCRPC) - MAESTROStatus unknownNCT03934164
• Phase I Trial of Defactinib and VS-6766.Active, not recruitingNCT03875820Phase 1
• The BARCODE 1 Study (Full Study): The Use of Genetic Profiling to Guide Prostate Cancer Targeted Screening.Active, not recruitingNCT03857477
• Transcriptional Responses as an Indicator of Individualised Responses to Radiation Effects (RTGene 2)Active, not recruitingNCT03809377
• A Trial of Ipatasertib in Combination With AtezolizumabActive, not recruitingNCT03673787Phase 1/2
• The eValuation of Image Guidance of Stereotactic Body Radiotherapy Using Ultrasound: Assessment in LiverStatus unknownNCT03592550
• Magnetic Resonance Guided High Intensity Focused Ultrasound (MRgHIFU) for Pain Palliation of Bone MetastasesWithdrawnNCT03479151Not applicable
• The Role of Hypoxia as a Selective Pressure for TP53 MutationsTerminatedNCT03466034
• Utilising CTC Counts to Optimize Systemic Therapy of Metastatic Prostate CancerTerminatedNCT03327662Phase 3
• Pimo Study: Extracellular Vesicle-based Liquid Biopsy to Detect Hypoxia in TumoursCompletedNCT03262311Not applicable
• Stereotactic Body Radiotherapy for the Treatment of OPDActive, not recruitingNCT03256981Phase 2/3
• The UK Plasma Based Molecular Profiling of Advanced Breast Cancer to Inform Therapeutic CHoices (plasmaMATCH) TrialStatus unknownNCT03182634Phase 2
• Combination Study of AZD5069 and Enzalutamide.TerminatedNCT03177187Phase 1/2
• The BARCODE 1 Pilot StudyActive, not recruitingNCT03158922
• A Trial Using ctDNA Blood Tests to Detect Cancer Cells After Standard Treatment to Trigger Additional Treatment in Early Stage Triple Negative Breast Cancer PatientsStatus unknownNCT03145961Phase 2
• The BARCODE 2 Study - The Use of Genetic Profiling to Guide Prostate Cancer TreatmentActive, not recruitingNCT02955082Phase 2
• Feasibility Study Testing Transcriptional Responses as an Indicator of Individualised Responses to Radiation EffectsCompletedNCT02780375
• KORTUC: Intra-tumoural Hydrogen Peroxide as a Radiation Sensitizer in Patients With Locally Advanced/Recurrent Breast Cancer in Terms of Toxicity and Tumour ResponseCompletedNCT02757651Phase 1/2
• Imaging NSCLC Treatment Response to ImmunotherapyCompletedNCT02753569
• MR-HIFU for Recurrent Gynaecological CancerCompletedNCT02714621Not applicable
• Assessing Treatment Response in Breast Cancer With Functional ImagingCompletedNCT02688257
• Imaging in Clinical Trials - a Questionnaire Study to Assess Impact of Imaging Regimes on Patient ParticipationCompletedNCT02541266
• A Study of Enzalutamide in Combination With AZD5363 in Patients With mCRPCStatus unknownNCT02525068Phase 2
• Study of Tumour Focused Radiotherapy for Bladder CancerActive, not recruitingNCT02447549Phase 2
• Imageguided Theranostics in Multiple MyelomaCompletedNCT02403102
• Evaluation of Clarity Ultrasound Guidance for Prostate TherapyCompletedNCT02388308
• Quantification of Breast RadioTherapy Associated Late Toxicity Using Novel UltraSound TechniquesCompletedNCT02388230
• Trial of Perioperative Endocrine Therapy - Individualising CareActive, not recruitingNCT02338310Phase 3
• International Penile Advanced Cancer Trial (International Rare Cancers Initiative Study)Active, not recruitingNCT02305654Phase 3
• Evolution of Resistance to Systemic Therapies in Patients With Breast CancerTerminatedNCT02257775
• Investigating Bladder Chemotherapy Instead of Surgery for Low Risk Bladder CancerStatus unknownNCT02070120Phase 2
• A Phase II Trial of Vinflunine Chemotherapy in Locally-advanced and Metastatic Carcinoma of the Penis (VinCaP)CompletedNCT02057913Phase 2
• A Phase III Randomised Trial of Peri-Operative Chemotherapy Versus sUrveillance in Upper Tract Urothelial Cancer (POUT)Status unknownNCT01993979Phase 3
• MR-HIFU for Bone MetastasesCompletedNCT01964677Not applicable
• Apparent Diffusion Coefficient as a Prognostic Biomarker in Cervical CancerCompletedNCT01937533
• Preoperative Imaging in Retroperitoneal SarcomaCompletedNCT01902667
• Lactate Imaging as a Tumour BiomarkerCompletedNCT01881386
• Magnetic Resonance Imaging Screening in Li Fraumeni SyndromeCompletedNCT01737255
• UK Genetic Prostate Cancer Study: Epidemiology and Molecular Genetics StudiesActive, not recruitingNCT01737242
• Trial of 1 Cycle of Adjuvant BEP Chemotherapy in High Risk, Stage 1 Non-seminomatous Germ Cell Testis TumoursCompletedNCT01726374Phase 3
• A Study of Prostate and pelvIs Versus prOsTate Alone Treatment for Locally Advanced Prostate CancerStatus unknownNCT01685190Phase 2
• TOPARP: A Phase II Trial of Olaparib in Patients With Advanced Castration Resistant Prostate CancerStatus unknownNCT01682772Phase 2
• MR Characterisation/Localisation of Breast CancerCompletedNCT01567137
• Diffusion-weighted Imaging Study in Cancer of the OvaryCompletedNCT01505829
• A Trial Looking at Nilotinib to Treat Acral and Mucosal Melanoma Skin Cancer That Has SpreadCompletedNCT01395121Phase 2
• A Trial of Cediranib in the Treatment of Patients With Alveolar Soft Part Sarcoma (CASPS)Status unknownNCT01337401Phase 2
• Intensity-Modulated Radiation Therapy or 3-Dimensional Conformal Radiation Therapy in Decreasing Hearing Loss in Patients Who Have Undergone Surgery for Parotid TumorsStatus unknownNCT01216800Phase 3
• 3-Dimensional Conformal Radiation Therapy in Treating Patients With Bladder Cancer Who Have Undergone Transurethral Resection of the BladderStatus unknownNCT01124682Phase 1
• Trastuzumab or Lapatinib Ditosylate in Treating Women With Early Breast CancerActive, not recruitingNCT01104571Phase 3
• Study of Blood and Tumor Samples From Men With an Inherited Risk of Prostate CancerStatus unknownNCT00959023
• Radiation Therapy or Surgery in Treating Patients Receiving Chemotherapy for Bladder CancerCompletedNCT00867347Phase 3
• Radiation Therapy in Treating Women Who Have Undergone Breast Conservation Surgery and Systemic Therapy for Early Breast CancerStatus unknownNCT00818051Phase 3
• Radiation Therapy in Women With Low Risk Early-Stage Breast Cancer Who Have Undergone Breast Conservation SurgeryStatus unknownNCT00814567Not applicable
• Triple Negative Breast Cancer TrialStatus unknownNCT00532727Phase 3
• Intensity-Modulated Radiation Therapy in Treating Patients With Localized Prostate CancerStatus unknownNCT00392535Not applicable
• Combination Chemotherapy in Treating Patients With Early Stage Breast Cancer That Has Been Removed By SurgeryStatus unknownNCT00301925Phase 3
• Short-term Presurgical Study to Assess Molecular Predictors of Lapatinib's Effects in Primary Breast CancerCompletedNCT00299286Phase 2
• The IMPACT Study - Identification of Men With a Genetic Predisposition to ProstAte CancerActive, not recruitingNCT00261456
• Combination Chemotherapy With or Without Surgery and Radiation Therapy in Treating Patients With Mesothelioma That Can Be Removed By SurgeryStatus unknownNCT00253409Not applicable

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