Duke University: Depressive Disorder trials

The registry lists 25 Depressive Disorder studies with Duke University as lead sponsor. 0 are open to participants now and 8 have results posted.

Phase 1 2Phase 2 5Phase 3 8Phase 4 1No phase 13(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Levomilnacipran ER vs. Adjunctive Quetiapine for Adults With Inadequate Relief With SSRIs in MDDCompletedNCT02720198Phase 3Results posted
• Switching From Generic Selective Serotonin Reuptake Inhibitors (SSRIs) and Selective Serotonin and Norepinephrine Reuptake Inhibitors (SNRIs) to Three Different Dose Initiation Strategies With VilazodoneCompletedNCT02015546Phase 3Results posted
• Antidepressant Plus Asenapine Versus Antidepressant Plus Placebo for DepressionCompletedNCT01670019Phase 4Results posted
• Trial of Collaborative Depression Care Management for HIV PatientsCompletedNCT01372605Not applicableResults posted
• Treatment of Mood and Marriage Study (TOMMS)CompletedNCT00612807Phase 1/2Results posted
• Pilot Study of Duloxetine in Psychological ResilienceCompletedNCT00331799Phase 2Results posted
• Exercise to Treat Depression in Individuals With Coronary Heart DiseaseCompletedNCT00302068Phase 3Results posted
• Antidepressant Medication Treatment for Depression in Individuals With Chronic Heart FailureCompletedNCT00078286Phase 2/3Results posted
• Latinx Teen Depression Treatment StudyCompletedNCT04819295
• Latina Adolescent Depression Treatment StudyCompletedNCT04164537
• Neurobehavioral Mechanisms of Emotion Regulation in Depression Across the Adult LifespanCompletedNCT03207503
• Predictors of Opioid-Induced Respiratory Depression (OIRD)CompletedNCT02473354Phase 1
• Treatment for Teens With Alcohol Abuse and DepressionCompletedNCT02227589Not applicable
• Perinatal Depression Treatment and Child DevelopmentCompletedNCT01826903
• Preliminary Study Examining Heart Failure Patients Responses to Depression EducationTerminatedNCT01794598Not applicable
• Cognitive Behavioral Treatments for Depression in Chronic IllnessCompletedNCT01208428Not applicable
• Escitalopram (Lexapro®) In Patients With Major Depression With Atypical FeaturesCompletedNCT00610506Phase 3
• Duke Conte Center for the Neuroscience of Depression in Late LifeCompletedNCT00576875
• Neurocognitive Outcomes of Depression in the ElderlyCompletedNCT00570583
• Antidepressant Safety in Kids StudyCompletedNCT00395213
• Effect of Brain Lesion Severity on Treatment Response in Late-Life DepressionCompletedNCT00339066Not applicable
• Exercise Training Versus Drug Therapy for Treating Depression in Older AdultsCompletedNCT00331305Phase 3
• Effects of Duloxetine vs. Escitalopram on Heart Rate Variability in DepressionCompletedNCT00215228Phase 2/3
• Modafinil for Atypical DepressionCompletedNCT00215176Phase 2/3
• Hostility, Depression, Social Environment and CHD RiskCompletedNCT00005533