Duke University: Tobacco Use Disorder trials

The registry lists 26 Tobacco Use Disorder studies with Duke University as lead sponsor. 2 are open to participants now and 13 have results posted.

Early Phase 1 1Phase 1 4Phase 2 8Phase 3 3No phase 12(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Project Q: Cue-based Treatment Intervention to Promote Cessation Among People Who Smoke Lightly or Non-dailyRecruitingNCT07425119Not applicable
• Neurobehavioral Mechanisms Linking Childhood Adversity to Increased Risk for SmokingRecruitingNCT05665465Early Phase 1
• Learn to Quit-HIV Pilot StudyCompletedNCT04609514Not applicableResults posted
• The Role of Nicotine Dose and Route of Delivery in Affecting Adoption of E-cigarettes and Reducing Exposure to Toxic Combustion ProductsCompletedNCT03492463Phase 2Results posted
• Self-activation in Individuals With and Without Nicotine DependenceTerminatedNCT03170258Not applicableResults posted
• Feasibility Trial of a Tailored Smoking Cessation App for People With Serious Mental IllnessCompletedNCT03069482Phase 1Results posted
• Combination Nicotine Patch / Lorcaserin for Smoking CessationCompletedNCT02906644Phase 2Results posted
• Adaptive Pharmacotherapy for Smoking CessationCompletedNCT02501265Phase 2Results posted
• Acute and Chronic Nicotine Modulation of Reinforcement LearningCompletedNCT01830842Not applicableResults posted
• Combination Bupropion / Varenicline for Smoking Cessation in Male SmokersCompletedNCT01806779Phase 2Results posted
• Tailored Smoking Cessation Treatment for LIVE FOR LIFE® ParticipantsTerminatedNCT01560507Phase 2/3Results posted
• Mechanistic Evaluations of Pre-Cessation Therapies for Smoking CessationCompletedNCT01406223Phase 3Results posted
• Concurrent Bupropion / Varenicline for Smoking CessationCompletedNCT01303861Phase 3Results posted
• A Controlled Laboratory Study of the Effects on Cue-Induced Craving in Dependent SmokersCompletedNCT00901459Phase 2Results posted
• Attention Deficit Hyperactivity Disorder (ADHD) Smoking Cessation StudyCompletedNCT00736255Not applicableResults posted
• Impact of New Standards for Tobacco Products Among Dual E-Cigarette/Combusted Cigarette Users - Project 2CompletedNCT05473585Not applicable
• Stage Ib Trial of mSMART With VareniclineWithdrawnNCT03069768Phase 1
• Reactions to Reduced Nicotine Cigarettes in Young Adult Low-Frequency SmokersCompletedNCT02989038Not applicable
• Study on Smoking Cessation and Cost Outcomes in the Duke Smoking Cessation ProgramTerminatedNCT02845687
• Study on Sit to Quit Phone InterventionCompletedNCT02840435Not applicable
• Stage Ib Trial of mSMART for Smoking Cessation Medication AdherenceStatus unknownNCT02635919Not applicable
• Effects of Nicotine Reduction on Smoking Behavior in ADHD SmokersTerminatedNCT02599571Not applicable
• The Role of Nicotine and Non-Nicotine Alkaloids in E-Cigarette Use and DependenceCompletedNCT02590393Phase 1/2
• Electronic Nicotine Delivery Systems as a Smoking Cessation TreatmentWithdrawnNCT02487953Phase 2
• p16 Methylation for Smoking CessationCompletedNCT01038492Not applicable
• Extinction Based Treatment for Nicotine DependenceCompletedNCT00831155Phase 1