An observational study in Childhood Acute Erythroleukemia (M6), Childhood Acute Megakaryocytic Leukemia (M7) and Childhood Acute Minimally Differentiated Myeloid Leukemia (M0), sponsored by Children's Oncology Group. Completed at 1 site in United States. Open to participants aged Up to 21 Years. Per ClinicalTrials.gov, last updated 2016-05-17.
Sponsored by Children's Oncology Group · Observational
This research study is studying identification of de novo Fanconi anemia in younger patients with newly diagnosed acute myeloid leukemia. Studying samples of tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to Fanconi anemia in patients with acute myeloid leukemia.
PRIMARY OBJECTIVES:
I. Identify children with newly diagnosed acute myeloid leukemia (AML) treated on COG-2961 and COG-AAML03P1 who are at high risk of having de novo Fanconi anemia.
II. Procure diagnostic samples from the COG AML Biology Repository and identify Fanconi anemia patients using western blot techniques.
OUTLINE:
Previously collected cryopreserved cells are analyzed via western blot to identify patients with Fanconi anemia.
5,441 studies on the registry are indexed under Leukemia; 636 are open to participants now.
This study's enrollment of 20 is below the median of 120 across 744 observational studies indexed under Leukemia.
Browse Leukemia studies →Children's Oncology Group is the lead sponsor of 436 studies on the registry; 34 are open to participants now.
Of its 12 completed or terminated interventional studies of FDA-regulated products, 11 (92%) have results posted.
Counted across the registry records on this site, refreshed daily.
Patients treated on trials COG-2961 or COG-AAML03P1. Also patients at high risk of having Fanconi anemia meeting other criteria.
Inclusion Criteria:
At high risk of having Fanconi anemia, defined as meeting one the following groups of clinical criteria:
Previously collected cryopreserved cells are analyzed via western blot to identify patients with Fanconi anemia.
Other: laboratory biomarker analysis
Correlative studies
Identification of children at high risk of having Fanconi anemia
Time frame: Up to 5 months
Identification of Fanconi anemia patients
Time frame: Up to 5 months
This study is completed, as verified in May 2016. You cannot join it, but the record below documents what was studied.
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Children's Oncology Group