Trientine clinical trials
Also written Syprine.
- studies test it
- 9
- open now
- 0
- in phase 3
- 0
- first study started
- 2010
How each study uses Trientine is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
Approvals
The first approval found in each region, with its record
- United States
- 8 Nov 1985 · SYPRINE · NDA 019194 (FDA, Drugs@FDA)
- European Union
- 5 Sept 2017 · Cuprior · EMEA/H/C/004005 (EMA)
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
How studies write it
Studies that test it under each name
Studies by the year they started
8 studies that test it; most in 2010 (3)
| Year | Studies |
|---|---|
| 2010 | 3 |
| 2012 | 1 |
| 2013 | 1 |
| 2014 | 1 |
| 2016 | 1 |
| 2020 | 1 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 2 · Other 7
Univar BV (2) · University of British Columbia (2) · Manchester University NHS Foundation Trust (1) · National Cheng-Kung University Hospital (1) · Yale University (1) · M.D. Anderson Cancer Center (1) · Duke University (1)
Often tested with
Tested in the same studies.
Carboplatin (2) · Liposomal doxorubicin (1) · Doxorubicin (1) · Vemurafenib (1)
Related medicines
As reviewed, each with the page that says it.
- One of Chelating Agents source
Studies
Open first, then newest update. How each study uses Trientine is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 9
- The Efficacy and Mechanism of Trientine in Patients With Hypertrophic CardiomyopathyCompletedPhase 2Manchester University NHS Foundation TrustNCT04706429Written as Trientine
- Trial of Trientine Plus Pegylated Liposomal Doxorubicin and Carboplatin in Epithelial Ovarian CancerCompletedPhase 1/2National Cheng-Kung University HospitalNCT03480750Written as trientine dihydrochloride
- Single Daily Dosage of Trientine for Maintenance Treatment for Wilson DiseaseCompletedNot applicableYale UniversityNCT01472874Written as Once a day Trientine
- A Pilot Study of Trientine With Vemurafenib for the Treatment BRAF Mutated Metastatic MelanomaWithdrawnPhase 1Duke UniversityNCT02068079Written as Vemurafenib and Trientine
- Trientine Hydrochloride for the Prevention of Macular Edema After Cataract Surgery in Patients With Type 2 Diabetes MellitusWithdrawnPhase 2University of British ColumbiaNCT01295073Written as Trientine Hydrochloride
- Study to Assess Long-Term Outcomes of Trientine in Wilson Disease Patients Withdrawn From Therapy With d-PenicillamineStatus unknownPhase 4Univar BVNCT02426905Written as trientine dihydrochloride
- Trientine and Carboplatin in Advanced MalignanciesCompletedPhase 1M.D. Anderson Cancer CenterNCT01178112Written as Trientine
- A Phase 1 Study to Assess the Effects in the Body of a Single Dose of Trientine Dihydrochloride in Wilson's Disease PatientsCompletedPhase 1Univar BVNCT01874028Written as trientine dihydrochloride
- Trientine Hydrochloride for the Prevention of Macular Edema Associated With Pan-retinal Photocoagulation for Severe Non-proliferative and Proliferative Diabetic RetinopathyTerminatedNot applicableUniversity of British ColumbiaNCT01213888Written as Trientine Hydrochloride
Codes
What other systems call Trientine · ClinicalTrials.gg INT008354
- MeSH (NLM) D014266TrientineConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) SJ76Y07H5FTRIENTINEConfirmed FDA, NLM
- RxNorm 10798One source FDA
- NCI Thesaurus C66633TrientineOne source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D014266 | Trientine | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | SJ76Y07H5F | TRIENTINE | Confirmed FDA, NLM |
| RxNorm | 10798 | — | One source FDA |
| NCI Thesaurus | C66633 | Trientine | One source FDA |
Also registered as trientine hydrochloride (UNII HC3NX54582 · RxNorm 235370).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.