5-HT3 antagonists: all 422 studies that test it
Page 4 of 5. Open to participants first (39), then studies with results posted, then the rest; newest registration first within each.
- Antagonism Research Between Antiemetics Agents and Acetaminophen in Thyroidectomy's Post-operative Analgesia.CompletedNCT01679093Phase 3
- Effects of Different Kinds, Different Doses of 5-HT3 Receptor Antagonists on Prevention of HypotensionStatus unknownNCT01669213Not applicable
- Ondansetron VS Doxylamine and Pyridoxine in Treating Nausea of PregnancyCompletedNCT01668069Not applicable
- Phase 4 Trial to Evaluate the Efficacy and Safety of Sancuso Patch in CINV (Chemotherapy-induced Nausea and Vomiting) Associated With the Administration of MEC (Moderately Emetogenic Chemotherapy)Status unknownNCT01662687Phase 4
- Efficacy of Aprepitant (Emend®) in ChildrenCompletedNCT01661335Phase 3
- Phase 4 Trial to Evaluate the Efficacy and Safety of Sancuso Patch in Chemotherapy-induced Nausea and Vomiting Associated With the Administration of Highly Emetogenic Chemotherapy (HEC)CompletedNCT01659775Phase 4
- The Effect of Palonosetron on the QTc Interval During Perioperative PeriodCompletedNCT01650961Not applicable
- Fosaprepitant Dimeglumine and Granisetron Transdermal System in Preventing Nausea and Vomiting in Patients With Breast Cancer Undergoing ChemotherapyTerminatedNCT01649258Phase 1
- Evaluation of Safety and Efficacy of Nasea(R)/Ramosetron Inj. in Patients Undergoing Facial Bone Fracture OperationsTerminatedNCT01637545Phase 4
- Randomized Double Blind Placebo Control Study in Patients with SchizophreniaCompletedNCT01602029Phase 2
- Safety and Pharmacokinetics of Sancuso and IV Granisetron in Patients Aged 2 to 5 YearsWithdrawnNCT01596426Phase 1
- Pharmacokinetics and Safety of Sancuso and IV Granisetron in Pediatrics Aged 6 to 12 YearsWithdrawnNCT01596413Phase 1
- Safety and Pharmacokinetics of Sancuso and IV Granisetron in Patients Aged 13 to 17 YearsCompletedNCT01596400Phase 1
- Pharmacogenetic Treatments for AlcoholismWithdrawnNCT01591291Phase 2/3
- Phase 1 Safety, Tolerability and PK Study of Ondansetron and Hylenex Recombinant in Healthy VolunteersCompletedNCT01572012Phase 1
- Therapeutic Efficacy and Safety of Palonosetron in Treatment of Postoperative Nausea and VomitingCompletedNCT01568268Phase 3
- Ramosetron, Aprepitant and Dexamethasone Versus Ondansetron, Aprepitant and DexamethasoneStatus unknownNCT01536691Phase 3
- Bioequivalence Study of Ondansetron Orally Disintegrating Tablets 8mg Under Fed ConditionsCompletedNCT01523119Not applicable
- Bioequivalence Study of Ondansetron Orally Disintegrating Tablets 8mg Under Fasting ConditionsCompletedNCT01523093Not applicable
- Bioequivalence Study for Ondansetron Hydrochloride Tablets 8 mg Under Fed ConditionCompletedNCT01511718Phase 1
- Bioequivalence Study for Ondansetron Hydrochloride Tablets 8 mg Under Fasting ConditionCompletedNCT01511705Phase 1
- Efficacy and Safety of Palonosetron Hydrochloride in the Prevention of Nausea and VomitingCompletedNCT01481831Phase 4
- The Effect of Ondansetron During Intramuscular Ketamine Use in Children: A Trial in Emergency DepartmentStatus unknownNCT01477242Not applicable
- To Investigate the Effect of Intravenous Ondansetron on Cardiac Conduction as Compared to Placebo and Moxifloxacin in Healthy Adult SubjectsCompletedNCT01449188Phase 1
- Comparison of Three Different Prophylactic Treatments of Postoperative Nausea and Vomiting (PONV) in ChildrenCompletedNCT01434017Phase 4
- Drug Interactions Between Paracetamol and Setrons in Pain ManagementCompletedNCT01432977Phase 3
- Effect of Ramosetron on Bowel Motility After Colorectal ResectionStatus unknownNCT01427127Phase 4
- Intravenous Ondansetron to Attenuate the Hypotensive, Bradycardic Response to Spinal Anesthesia in Healthy ParturientsCompletedNCT01414777Phase 2/3
- A Study to Compare Oral Absorption of YM060 Between Orally-disintegrating Tablet and Conventional Tablet Under With Water IntakeCompletedNCT01394653Phase 1
- A Study to Compare Oral Absorption of YM060 Between Orally-disintegrating Tablet (Without Water) and Conventional TabletCompletedNCT01392794Phase 1
- PHASE IIA: Trial of a Novel Ondansetron Formulation (OND-PR002) and Immediate-Release Methylphenidate (Ritalin®)(OND003IND)CompletedNCT01377662Phase 2
- Granisetron Versus Ondansetron: Comparative Effects on ECG, QTcCompletedNCT01352130Phase 4
- Ondansetron Augmentation in Treatment-resistant OCDCompletedNCT01303536Phase 4
- Efficacy and Safety Study of Low-Dose Ondansetron For Adjunctive Therapy In Adult Patients With Obsessive-Compulsive DisorderTerminatedNCT01275248Phase 2
- A Study to Evaluate Efficacy of YM060 on Diarrhea-predominant Irritable Bowel Syndrome (D-IBS) in Female PatientsCompletedNCT01274000Phase 2
- Symptomatic Treatment of Acute GastroenteritisCompletedNCT01257672Phase 3
- A Study to Evaluate Efficacy of Ramosetron on Diarrhea-predominant Irritable Bowel Syndrome (IBS) in Male PatientsCompletedNCT01225237Phase 4
- Prophylactic Effects of Ondansetron, Ramosetron, and Palonosetron on Patient-Controlled Analgesia Related Nausea and Vomiting After Urologic Laparoscopic SurgeryCompletedNCT01169805Not applicable
- Double Blind, Placebo-Controlled, Randomised Investigation of Ondansetron in SchizophreniaCompletedNCT01121042Phase 3
- Matching Genotypes and Serotonergic Medications for AlcoholismCompletedNCT01113164Phase 1
- Aprepitant for Prevention of Acute and Delayed Nausea and Vomiting in Patients Receiving a High-emetogenic Dose of Cyclophosphamide for Peripheral Blood Stem Cells HarvestingStatus unknownNCT01088022Phase 3
- Effect of External Heat on a Transdermal Granisetron Patch in Pharmacokinetics (PK) of Healthy SubjectsCompletedNCT01073696Phase 1
- Rescue Emetic Therapy for Children Having Elective SurgeryWithdrawnNCT01067677Not applicable
- Scottish and Newcastle Anti-emetic Pre-treatment for Paracetamol Poisoning Study (SNAP)CompletedNCT01050270Phase 4
- Ramosetron, Aprepitant and Dexamethasone (RAD) in Solid CancerStatus unknownNCT01046461Phase 2
- Pharmacokinetic Evaluation of Subcutaneous Versus Intravenous Palonosetron in Cancer Treated With ChemotherapyCompletedNCT01046240Phase 1/2
- The Effect of Oral and Intravenous Ramosetron During Laparoscopic CholecystectomyStatus unknownNCT01041183Not applicable
- Pharmacokinetic Study of Ondansetron Administered as IR (Zofran) and MR (EUR1025)CompletedNCT01036854Phase 1
- Study With Palonosetron Alone in Preventing Chemotherapy-induced Nausea and Vomiting in Untreated Patients With Aggressive Non Hodgkin's Lymphomas Who Underwent Moderately Emetogenic ChemotherapyCompletedNCT01018758Phase 2
- Efficacy of Dexamethasone Added to Ramosetron for Preventing Postoperative Nausea and Vomiting in Highly Susceptible Patients Following Spine SurgeryCompletedNCT01013012Phase 4
- Bioavailability Study of Anti Nausea Medication With and Without Food (EUR-1025)CompletedNCT00981487Phase 1
- Ramosetron Versus Ondansetron for Radiotherapy Induced Nausea and VomitingCompletedNCT00971399Phase 3
- Effectiveness of Aprepitant in Addition to Ondansetron in the Prevention of Nausea and Vomiting Caused by Upper Abdominal RadiotherapyCompletedNCT00970905Phase 2
- The Central Analgesic Effects of Paracetamol on Serotonergic PathwaysCompletedNCT00970450Not applicable
- To Demonstrate the Relative Bioavailability Study of Ondansetron HCl 24 mg Tablets Under Non-Fasting ConditionsCompletedNCT00947128Phase 1
- To Demonstrate the Relative Bioavailability Study of Ondansetron HCl 24 mg Tablets Under Fasting ConditionsCompletedNCT00946387Phase 1
- Role of Anti-Inflammatory Agents in Patients With SchizophreniaCompletedNCT00929955Phase 1
- A Preliminary Study to Explore Clinical Endpoints in Patients (Male) With Diarrhea-predominant Irritable Bowel SyndromeCompletedNCT00918411Phase 4
- Late Onset Postoperative Nausea and VomitingCompletedNCT00918190Not applicable
- Bioavailability Study of Anti Nausea Medication With and Without FoodCompletedNCT00905190Phase 1
- Safety Study of Electrocardiogram (ECG) Effects of Sancuso® (Granisetron TDS)CompletedNCT00890565Phase 1
- Ondansetron for the Treatment of Heavy Drinking Among Emerging AdultsTerminatedNCT00890149Phase 2
- PK, Tolerability and Safety of the Co-administration of Sancuso® (Transdermal Granisetron) and IV GranisetronCompletedNCT00873197Phase 1
- An Investigation on the Effect of Age and BMI on the Pharmacokinetics of Transdermal GranisetronCompletedNCT00868764Phase 1
- Dexamethasone for Postoperative Nausea and VomitingCompletedNCT00825071Phase 4
- Efficacy of Dolasetron in Patients With FibromyalgiaCompletedNCT00820326Phase 3
- Ondansetron in Treatment Resistant Obsessive Compulsive Disorder (OCD)CompletedNCT00796497Phase 4
- Depth of Hypnosis and Postoperative Nausea and Vomiting During Xenon AnaesthesiaCompletedNCT00793663Phase 4
- Uncomplicated Nausea and Vomiting in the Emergency DepartmentCompletedNCT00778011Phase 4
- Combined Pharmacotherapies for AlcoholismCompletedNCT00768508Phase 3
- Ondansetron for the Treatment of IBS With Diarrhoea (IBS-D)CompletedNCT00745004Phase 4
- Combination Antiemetic Regimen for Prevention of PONV in Breast Surgery PatientsCompletedNCT00738621Phase 4
- Efficacy Study of IV Fluids Only vs Ondansetron to Treat DehydrationWithdrawnNCT00691275Not applicable
- Palonosetron Plus Dexamethasone in Moderately Emetogenic Chemotherapy Induced Nausea and Vomiting (Study P04594)CompletedNCT00687011Phase 4
- Palonosetron in Moderately and Highly Emetogenic Chemotherapy Induced Nausea and Vomiting (Study P04935)(COMPLETED)CompletedNCT00684463Phase 4
- Ondansetron With Olanzapine for the Treatment of Alcohol Dependence: A Preliminary Clinical TrialCompletedNCT00678457Phase 2
- An Efficacy and Safety Study of Palonosetron in Preventing Chemotherapy-Induced Nausea and Vomiting (CINV) in the Chinese Cancer PatientsCompletedNCT00666783Phase 2
- Bioavailability Study of Ondansetron 16 mg Orally Disintegrating Tablets Under Fasting ConditionsCompletedNCT00659685Phase 1
- Bioavailability Study of Ondansetron 24 mg Orally Disintegrating Tablets Under Fasting ConditionsCompletedNCT00659074Phase 1
- Bioavailability Study of Ondansetron Orally Disintegrating Tablets Under Fasting ConditionsCompletedNCT00654277Phase 1
- Bioavailability Study of Ondansetron Orally Disintegrating Tablets Under Fed ConditionsCompletedNCT00653458Phase 1
- Fasting Study of Ondansetron Tablets 24 mg and Zofran® Tablets 24 mgCompletedNCT00649532Phase 1
- Food Study of Ondansetron Tablets 24 mg and Zofran® Tablets 24 mgCompletedNCT00648583Phase 1
- The Effects of the Anti Nausea Drugs Droperidol and Ondansetron on the Way the Heart Recovers Between BeatsCompletedNCT00624208Not applicable
- A Single Dose, 4-Period, 2-Treatment Replicate Design Bioequivalency Study of Granisetron Hydrochloride 1 mg Tablets Under Fasting ConditionsCompletedNCT00618254Not applicable
- A Single Dose, 4-Period, 2-Treatment Replicate Design Bioequivalency Study of Granisetron Hydrochloride 1 mg Tablets Under Fed ConditionsCompletedNCT00618111Not applicable
- Pharmacotherapy for HIV+ Stimulant Dependent IndividualsStatus unknownNCT00599573Not applicable
- The Pharmacokinetic Interaction Between Oral Casopitant and Oral Dolasetron, Granisetron or Rosiglitazone in SubjectsCompletedNCT00511823Phase 1
- Safety and Efficacy of Palonosetron in Preventing Chemotherapy-induced Nausea and VomitingCompletedNCT00503386Phase 2
- The Antigagging Effect of Granisetron (Kytril), an Antiemetic Drug, in Dental SituationsStatus unknownNCT00502437Not applicable
- Aprepitant or Ondansetron in Treating Nausea and Vomiting Caused By Opioids in Patients With CancerWithdrawnNCT00499668Not applicable
- Clinical Confirmation of a Pharmacodynamic Interaction Between Tropisetron and ParacetamolCompletedNCT00487110Phase 4
- Randomized Crossover Pharmacokinetic Evaluation of Subcutaneous Versus Intravenous Granisetron in Cancer PatientsCompletedNCT00450853Phase 2
- A Study to Assess the Safety & Interaction Between GW679769, Dexamethasone, & Ondansetron When Taken by Healthy AdultsCompletedNCT00437229Phase 1
- A RCT of Ondansetron and Promethazine in the Treatment of Nausea and Vomiting in the Emergency DepartmentCompletedNCT00429832Phase 4
- AMENO-2: Aprepitant Plus Palonosetron Versus Granisetron in the Prevention of Nausea and the Emesis Induced by Chemotherapy in Patients Treated With Haematopoietic ProgenitorsCompletedNCT00415103Phase 4
- Ondansetron Reduce Vomiting Associated With Ketamine PSACompletedNCT00387556Not applicable
- Pharmacological Treatment for AlcoholismCompletedNCT00382642Phase 3
- Comparative Study of Palonosetron With Granisetron as a Control in Patients Receiving Highly Emetogenic ChemotherapyCompletedNCT00359567Phase 3
- Safety and Efficacy Study for the Prevention of Nausea and Vomiting in Multiple Myeloma Patients Receiving Stem Cell Transplantation.CompletedNCT00306735Phase 2