Drug
Seltorexant clinical trials
Also written JNJ-42847922 and MIN-202;.
- studies test it
- 33
- open now
- 2
- in phase 3
- 5
- first study started
- 2014
Keep track of what changes. Save the seltorexant studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Development codes
Studies by the year they started
33 studies that test it; most in 2015 (7)
| Year | Studies |
|---|---|
| 2014 | 2 |
| 2015 | 7 |
| 2016 | 2 |
| 2017 | 4 |
| 2018 | 4 |
| 2019 | 1 |
| 2020 | 5 |
| 2021 | 4 |
| 2022 | 2 |
| 2024 | 1 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 23
- Phase 2
- 5
- Phase 3
- 5
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 33 · Other 0
Janssen Research & Development, LLC (27) · Janssen-Cilag International NV (4) · Janssen Cilag N.V./S.A. (1) · Janssen Pharmaceutical K.K. (1)
Often tested with
Tested in the same studies.
Zolpidem (2) · Diphenhydramine (1) · Ethinyl Estradiol (1) · Levonorgestrel (1) · Zopiclone (1) · Rabeprazole (1) · Rifampin (1) · Itraconazole (1)
Studies
Open first, then newest update. How each study uses seltorexant is read from its arms, and is right about nine times in ten.
Testing it · 33
- A Study of Seltorexant as Monotherapy in Adults and Elderly Participants With Major Depressive DisorderRecruitingPhase 3Janssen Research & Development, LLCNCT07573176Written as Seltorexant
- Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia SymptomsRecruitingPhase 3Janssen Research & Development, LLCNCT06559306Written as Seltorexant
- A Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant and Long-term Safety Extension Treatment With SeltorexantCompletedPhase 3Janssen Research & Development, LLCNCT04533529Written as Seltorexant
- A Study of Seltorexant Compared to Quetiapine XR as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant TherapyCompletedPhase 3Janssen Research & Development, LLCNCT04513912Written as Seltorexant
- A Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant TherapyTerminatedPhase 3Janssen Research & Development, LLCNCT04532749Written as Seltorexant
- A Study to Compare the Efficacy, Safety, and Tolerability of JNJ-42847922 Versus Quetiapine Extended-Release as Adjunctive Therapy to Antidepressants in Adult Participants With Major Depressive Disorder Who Have Responded Inadequately to Antidepressant TherapyCompletedPhase 2Janssen Research & Development, LLCNCT03321526Written as JNJ-42847922
- A Study to Evaluate the Efficacy and Safety of JNJ-42847922 as Adjunctive Therapy to Antidepressants in Adult Participants With Major Depressive Disorder Who Have Responded Inadequately to Antidepressant TherapyCompletedPhase 2Janssen Research & Development, LLCNCT03227224Written as JNJ-42847922
- A Study to Evaluate the Efficacy, Safety, and Tolerability of JNJ-42847922 in Participants With Insomnia DisorderCompletedPhase 2Janssen Research & Development, LLCNCT03375203Written as JNJ-42847922, 5 mg
- A Study of Seltorexant in Participants With Probable Alzheimer's DiseaseCompletedPhase 2Janssen Research & Development, LLCNCT05307692Written as Seltorexant
- A Study of Seltorexant (JNJ-42847922) After Single-Dose Administration in Healthy ParticipantsCompletedPhase 1Janssen Research & Development, LLCNCT03682380Written as Seltorexant High Dose
- A Study to Assess the Effect of Seltorexant Compared to Placebo on Respiration During Sleep in Adult Participants With Obstructive Sleep ApneaCompletedPhase 1Janssen Research & Development, LLCNCT03796026Written as Seltorexant 40 mg
- A Safety, Efficacy and Biomarker Study of JNJ-42847922 in Participants With Major Depressive DisorderCompletedPhase 1Janssen-Cilag International NVNCT02476058Written as JNJ-42847922
- A Study to Evaluate the Effect of Hepatic Impairment on JNJ-42847922 in Adult ParticipantsCompletedPhase 1Janssen Research & Development, LLCNCT04960124Written as JNJ-42847922
- A Study of JNJ-42847922 (Seltorexant) in Healthy ParticipantsCompletedPhase 1Janssen Research & Development, LLCNCT05236868Written as Seltorexant
- Study to Evaluate Efficacy, Safety and Tolerability of JNJ-42847922 in Participants With Insomnia Disorder Without Psychiatric ComorbidityCompletedPhase 2Janssen Research & Development, LLCNCT02464046Written as JNJ-42847922
- A Study of Seltorexant in Healthy ParticipantsCompletedPhase 1Janssen Research & Development, LLCNCT04553042Written as Seltorexant
- A Study to Evaluate the Effect of Multiple Oral Doses of JNJ-42847922 on the Steady-state Pharmacokinetics of an Oral Contraceptive Containing Ethinyl Estradiol and Levonorgestrel in Healthy Female Adult ParticipantsCompletedPhase 1Janssen-Cilag International NVNCT03249402Written as JNJ-42847922
- A Study of Oral Seltorexant as an add-on Medication to an Antidepressant on On-road Driving Performance in Participants With Major Depressive DisorderCompletedPhase 1Janssen Research & Development, LLCNCT04451187Written as Seltorexant Dose 1
- A Study to Investigate the Antidepressant Mechanism-of-action of JNJ-42847922 in Participants With Major Depressive DisorderCompletedPhase 1Janssen Research & Development, LLCNCT03374475Written as JNJ-42847922 20mg
- A Study to Evaluate the Effects of Single-dose Seltorexant on Electrocardiogram Intervals in Healthy Adult ParticipantsCompletedPhase 1Janssen Research & Development, LLCNCT03494907Written as Seltorexant
Codes
What other systems call seltorexant · ClinicalTrials.gg INT001223
- MeSH (NLM) C000655226seltorexantOne source NLM
- UNII (FDA) AIS8N3O50BSELTOREXANTConfirmed FDA, NLM, Wikidata
- Wikidata Q27273944seltorexantConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C152326SeltorexantOne source FDA
- DrugBank DB14961One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C000655226 | seltorexant | One source NLM |
| UNII (FDA) | AIS8N3O50B | SELTOREXANT | Confirmed FDA, NLM, Wikidata |
| Wikidata | Q27273944 | seltorexant | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C152326 | Seltorexant | One source FDA |
| DrugBank | DB14961 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.