Selective Serotonin Reuptake Inhibitors: all 1,366 studies that test it

Page 3 of 14. Open to participants first (105), then studies with results posted, then the rest; newest registration first within each.

• SSRI Effects on Depression and Immunity in HIV/AIDSCompletedNCT02620150Phase 4Results posted
• The Effects of Antipsychotic Drugs on Brain Metabolism in Healthy IndividualsCompletedNCT02536846Phase 4Results posted
• Vortioxetine for Binge Eating DisorderCompletedNCT02528409Phase 2Results posted
• PTSD Prevention Study Examining the Efficacy of Sertraline in Burn VictimsTerminatedNCT02520726Phase 4Results posted
• Exercise and Pharmacotherapy for Anxiety in Cardiac PatientsCompletedNCT02516332Not applicableResults posted
• Serotonin Selective Reuptake Inhibitor Treatment of Dual Diagnosis Post-traumatic Stress Disorder and Alcohol ProblemsCompletedNCT02504931Phase 4Results posted
• Aprepitant ,Olanzapine,Palonosetron and Dexamethasone for the Prevention of Chemotherapy-induced Nausea and VomitingCompletedNCT02484911Phase 3Results posted
• The Serotonin Transporter Availability for Prognosing Major Depressive Disorder (MDD) Treatment and Detecting MDDCompletedNCT02473783Phase 2Results posted
• Prediction of Clinical Response to SSRI Treatment in Bipolar Disorder Using Serotonin 1A Receptor PET ImagingCompletedNCT02473250Phase 4Results posted
• A Study to Assess the Clinical Utility of Antipsychotic Medication Levels in Plasma as Determined by Liquid Chromatography-Tandem Mass SpectrometryTerminatedNCT02462473Phase 2Results posted
• eIMPACT Trial: Modernized Collaborative Care to Reduce the Excess CVD Risk of Older Depressed PatientsCompletedNCT02458690Phase 2Results posted
• Role of Enhancing Serotonin Receptors Activity for Sleep Apnea Treatment in Patients With SCICompletedNCT02458469Phase 2Results posted
• A Study of Vilazodone in Pediatric Patients With Major Depressive DisorderCompletedNCT02436239Phase 3Results posted
• A Phase 3 Study of Lu AA21004 in Patients With Major Depressive DisorderCompletedNCT02389816Phase 3Results posted
• 16-week Comparative Effectiveness Trial of Lamotrigine vs. Fluoxetine for Bipolar DepressionTerminatedNCT02389712Phase 4Results posted
• Stress and Inflammation in Late-Life DepressionCompletedNCT02389465Phase 4Results posted
• A Trial of Sertraline in Young Children With Autism Spectrum DisorderCompletedNCT02385799Phase 2Results posted
• Safety and Efficacy of Vilazodone in Pediatric Patients With Major Depressive Disorder (VLZ-MD-22)CompletedNCT02372799Phase 3Results posted
• Vortioxetine, 5, 10, and 20 mg, Relapse Prevention Study in Adults With Major Depressive Disorder (MDD)CompletedNCT02371980Phase 4Results posted
• Fluoxetine vs Aripiprazole Comparative Trial (FACT)TerminatedNCT02357849Phase 4Results posted
• Connectivity Affecting the Antidepressant REsponse StudyCompletedNCT02332291Phase 4Results posted
• Investigating the Effect of Vortioxetine in Adult ADHD PatientsCompletedNCT02327013Phase 2Results posted
• Prophylactic Use of Postpartum Sertraline to Prevent Postpartum DepressionTerminatedNCT02235064Not applicableResults posted
• Vortioxetine for Menopausal DepressionCompletedNCT02234362Phase 4Results posted
• Effects rTMS Combined With Fluoxetine on Motor Recovery in Stroke PatientsCompletedNCT02208466Phase 2Results posted
• Treatment of Pediatric Anxiety Disorders by Predicting Treatment Response Through Biocellular Markers and SleepTerminatedNCT02189213Not applicableResults posted
• Pharmacokinetics, Safety and Tolerability of Vortioxetine in Normal Hepatic Function or Severe Hepatic ImpairmentCompletedNCT02170220Phase 1Results posted
• A Study of ALKS 3831 in Subjects With Schizophrenia and Alcohol Use DisorderCompletedNCT02161718Phase 2Results posted
• Escitalopram Effects on CSF Amyloid BetaCompletedNCT02161458Phase 4Results posted
• The ISLAND Study: InSuLa Assessed Needs for DepressionCompletedNCT02137369Phase 4Results posted
• Olanzapine for Prevention of Chemotherapy-induced Nausea and Vomiting in Children: A Multi-Centre Feasibility StudyCompletedNCT02129478Phase 2Results posted
• Antiemetic Therapy With or Without Olanzapine in Preventing Chemotherapy-Induced Nausea and Vomiting in Patients With Cancer Receiving Highly Emetogenic ChemotherapyCompletedNCT02116530Phase 3Results posted
• Pilot Study of Olanzapine and Aprepitant to Prevent Nausea and Vomiting in Children Receiving ChemotherapyCompletedNCT02097823Phase 2Results posted
• Developing New Clinical Management StrategiesCompletedNCT02082392Phase 4Results posted
• Brain Function and Structure in Cocaine DependenceCompletedNCT02080832Phase 2Results posted
• An Adaptive Treatment Strategy for Adolescent Depression-ContinuationCompletedNCT02017535Phase 1/2Results posted
• Switching From Generic Selective Serotonin Reuptake Inhibitors (SSRIs) and Selective Serotonin and Norepinephrine Reuptake Inhibitors (SNRIs) to Three Different Dose Initiation Strategies With VilazodoneCompletedNCT02015546Phase 3Results posted
• Vilazodone for Separation Anxiety DisorderCompletedNCT01999920Phase 4Results posted
• Sequencing CBT for Child Anxiety: CBT Plus Sertraline Versus Switch to SertralineTerminatedNCT01977729Phase 2Results posted
• A Phase 3 Study of Fluvoxamine (SME3110) in Pediatric/Adolescent Patients With Obsessive Compulsive DisorderCompletedNCT01933919Phase 3Results posted
• Mechanisms of Antidepressant Non-Response in Late-Life DepressionCompletedNCT01931202Not applicableResults posted
• Assessment and Comparison of Metabolic Changes in Non-psychotic Adults Taking Iloperidone or Olanzapine or PlaceboCompletedNCT01920802Phase 4Results posted
• Placebo Effects in the Treatment of Depression: Cognitive and Neural MechanismsCompletedNCT01919216Phase 4Results posted
• Frontal Hypoperfusion Effects on Antidepressant Outcomes in Late-Life DepressionCompletedNCT01896934Phase 4Results posted
• Safety and Efficacy of Vilazodone in Adolescent Patients With Major Depressive DisorderCompletedNCT01878292Phase 3Results posted
• Memantine Plus Es-citalopram in Elderly Depressed Patients With Cognitive ImpairmentCompletedNCT01876823Phase 2/3Results posted
• A Study to Evaluate the Impact of Escitalopram on Quality of Life and Social Functionality in Patients With Major Depressive Disorder With Anxiety SymptomCompletedNCT01870843Phase 4Results posted
• Safety, Efficacy and Tolerability of Vilazodone in (GAD) Generalized Anxiety DisorderCompletedNCT01844115Phase 3Results posted
• Pharmacokinetic Evaluation of Brisdelle™ (Formerly Known as Mesafem) Following Single & Repeat Oral Administration in Healthy Postmenopausal WomenCompletedNCT01829919Phase 1Results posted
• Vilazodone for Corticosteroid-Induced Memory ImpairmentCompletedNCT01828515Phase 2Results posted
• The Effects of Trazodone on Sleep Apnea SeverityCompletedNCT01817907Not applicableResults posted
• Differentiating Unipolar and Bipolar Depression in Young Adults Using fMRICompletedNCT01811147Phase 4Results posted
• A Study of Fluoxetine in Major Depressive Disorder (MDD) Long-Term DosingCompletedNCT01808651Phase 3Results posted
• A Study of Fluoxetine in Major Depressive Disorder (MDD) Short-Term DosingCompletedNCT01808612Phase 3Results posted
• An Adaptive Treatment Strategy for Adolescent DepressionCompletedNCT01802437Phase 1/2Results posted
• Adjunctive Sertraline for the Treatment of HIV-Associated Cryptococcal MeningitisCompletedNCT01802385Phase 3Results posted
• A Trial Examining the Efficacy of Escitalopram Oxalate Upon Depressive Symptoms and Fatigue in HIV Seropositive WomenTerminatedNCT01797380Phase 4Results posted
• Effects of Cerebral Hypoperfusion and Its Reversal on Late-Life DepressionTerminatedNCT01794455Phase 4Results posted
• Neurobiological Bases of Placebo Response in Major Depressive DisorderTerminatedNCT01787240Phase 4Results posted
• Evaluation of [11C]Cimbi-36 as an Agonist PET Radioligand for Imaging of 5-HT2A ReceptorsCompletedNCT01778686Not applicableResults posted
• Paroxetine/Bupropion in Depression With Suicide Attempt or Thoughts: fMRI StudyCompletedNCT01748955Phase 4Results posted
• Double-Blind Treatment of Major Depressive Disorder With VilazodoneCompletedNCT01742832Phase 2Results posted
• Emotional and Cognitive Control in Late-Onset DepressionCompletedNCT01728194Phase 4Results posted
• An Objective Double-blind Evaluation of Bupropion and Citalopram in an Individual With Friedreich AtaxiaCompletedNCT01716221Phase 4Results posted
• Characterization and Sequential Pharmacotherapy of Severe Mood DysregulationCompletedNCT01714310Phase 2Results posted
• A Study of Olanzapine and Fluoxetine for Treatment-resistant DepressionTerminatedNCT01687478Phase 3Results posted
• Neural Circuits in Women With Abuse and Posttraumatic Stress DisorderCompletedNCT01681849Phase 4Results posted
• Vilazodone for Menopausal Hot FlashesCompletedNCT01680900Not applicableResults posted
• Comparison of Quetiapine and Trazodone Treatment for Insomnia in Dually Diagnosed VeteransTerminatedNCT01662297Phase 4Results posted
• Combination Treatment Study for Memory Impairment and DepressionCompletedNCT01658228Phase 4Results posted
• Citalopram Effects on Craving and Dopamine Receptor Availability in AlcoholicsCompletedNCT01657760Phase 1Results posted
• Sequenced Therapies for Comorbid and Primary InsomniasCompletedNCT01651442Not applicableResults posted
• Homeopathic Treatment for Depression in Peri- and Postmenopausal WomenCompletedNCT01635218Phase 2Results posted
• Safety, Efficacy and Tolerability of Vilazodone in Generalized Anxiety DisorderCompletedNCT01629966Phase 3Results posted
• A Pilot Study on the Efficacy and Safety of Olanzapine in GastroparesisTerminatedNCT01625923Not applicableResults posted
• Vilazodone for Treatment of Geriatric DepressionCompletedNCT01608295Phase 4Results posted
• Vilazodone Treatment for Marijuana DependenceCompletedNCT01574183Phase 2Results posted
• Study of Vortioxetine (Lu AA21004) in Major Depressive Disorder in Asian CountriesCompletedNCT01571453Phase 3Results posted
• A Study of LY110140 in Healthy Japanese Male ParticipantsCompletedNCT01569126Phase 1Results posted
• Efficacy of Lu AA21004 on Cognitive Dysfunction in Major Depressive DisorderCompletedNCT01564862Phase 2Results posted
• Glutamatergic and GABAergic Mediators of Antidepressant Response in Major DepressionCompletedNCT01557946Phase 4Results posted
• Repeated Partial Sleep Deprivation to Augment SSRI Response in DepressionCompletedNCT01545843Phase 2Results posted
• Citalopram for Cocaine DependenceCompletedNCT01535573Phase 2Results posted
• PROlonGed ExpoSure SertralineCompletedNCT01524133Phase 4Results posted
• Metabolic Effects of Olanzapine in Healthy MalesCompletedNCT01496183Not applicableResults posted
• Pharmacokinetics and Tolerability of Vortioxetine (Lu AA21004) in Child and Adolescent Patients With Depressive or Anxiety DisorderCompletedNCT01491035Phase 2Results posted
• A Study of Vortioxetine (Lu AA21004) in Comparison to Agomelatine in Adults Suffering From Major Depression With Inadequate Response to Previous MedicationCompletedNCT01488071Phase 3Results posted
• Trial of Sertraline to Treat Children With Fragile X SyndromeCompletedNCT01474746Phase 2Results posted
• Safety, Efficacy, and Tolerability of Vilazodone in Major Depressive DisorderCompletedNCT01473394Phase 4Results posted
• Safety and Efficacy of Vilazodone in Major Depressive DisorderCompletedNCT01473381Phase 4Results posted
• The Effects of Sertraline on Depression in Parkinson's DiseaseCompletedNCT01437189Not applicableResults posted
• Sustaining Remission of Psychotic DepressionCompletedNCT01427608Phase 4Results posted
• Efficacy Study of Vortioxetine on Cognitive Dysfunction in Adult Patients With Major Depressive DisorderCompletedNCT01422213Phase 3Results posted
• Establishing Moderators and Biosignatures of Antidepressant Response for Clinical Care for DepressionCompletedNCT01407094Phase 2Results posted
• Brain Imaging and Treatment Studies of the Night Eating SyndromeCompletedNCT01401595Phase 3Results posted
• Influence of Escitalopram on Fear ConditioningCompletedNCT01398514Phase 4Results posted
• A Study of LY2216684 in Participants With Major Depression DisorderCompletedNCT01370499Phase 3Results posted
• Lexapro for the Treatment of Traumatic Brain Injury (TBI) Depression & Other Psychiatric ConditionsCompletedNCT01368432Phase 2Results posted
• Vortioxetine (Lu AA21004) 10 and 20 mg for Treatment of Major Depressive Disorder With Sexual DysfunctionCompletedNCT01364649Phase 3Results posted
• Efficacy/Safety Study of Brisdelle™ (Formerly Known as Mesafem) in the Treatment of Vasomotor Symptoms (VMS)CompletedNCT01361308Phase 3Results posted

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