Drug
Radium clinical trials
Includes 35 studies of Radium Ra 223 dichloride and 16 studies of Radium-223.
- studies test it
- 52
- open now
- 1
- in phase 3
- 7
- first study started
- 2004
Keep track of what changes. Save the Radium studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesStudies by the year they started
52 studies that test it; most in 2015 (8)
| Year | Studies |
|---|---|
| 2004 | 1 |
| 2005 | 1 |
| 2006 | 1 |
| 2007 | 1 |
| 2008 | 2 |
| 2010 | 1 |
| 2012 | 3 |
| 2013 | 4 |
| 2014 | 7 |
| 2015 | 8 |
| 2016 | 5 |
| 2017 | 4 |
| 2018 | 4 |
| 2019 | 1 |
| 2020 | 5 |
| 2022 | 1 |
| 2023 | 1 |
| 2024 | 1 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 1
- Phase 1
- 14
- Phase 2
- 33
- Phase 3
- 7
- Phase 4
- 2
- No phase
- 1
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 23 · Other 29
Bayer (22) · University of Utah (3) · M.D. Anderson Cancer Center (3) · Memorial Sloan Kettering Cancer Center (2) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (2) · National Cancer Institute (NCI) (1) · University of California, San Francisco (1) · European Organisation for Research and Treatment of Cancer - EORTC (1)
Often tested with
Tested in the same studies.
Docetaxel (2) · Enzalutamide (2) · Atezolizumab (2) · Nivolumab (1) · Dexamethasone (1) · Abiraterone Acetate (1) · Abiraterone (1) · Prednisone (1)
Studies
Open first, then newest update. How each study uses Radium is read from its arms, and is right about nine times in ten.
Testing it · 52
- Radium-223 for High-Volume Metastatic Hormone Sensitive Prostate CancerNot yet recruitingPhase 2Alianza multidisciplinar para la investigación de los tumores genitourinarios -GUARDNCT07717099Written as Ra223
- RADIANT: A Study of Radium-223 Dichloride (Xofigo) vs Enzalutamide or Abiraterone (ARPIs, Androgen Receptor Pathway Inhibitors) in Patients With Prostate Cancer That Has Spread to the Bones (mCRPC, Metastatic Castration-Resistant Prostate Cancer)Active, not recruitingPhase 4BayerNCT04597125Written as Radium-223 dichloride (Xofigo, BAY88-8223)
- Study of Nivolumab in Combination w Radium-223 in Men w Metastatic Castration Resistant Prostate CancerActive, not recruitingPhase 1University of UtahNCT04109729Written as Radium-223
- A Study to Test Radium-223 With Docetaxel in Patients With Prostate CancerActive, not recruitingPhase 3Memorial Sloan Kettering Cancer CenterNCT03574571Written as Radium-223
- Radium-223 in Combination With EnzalutamideCompletedPhase 2Cancer Trials IrelandNCT02225704Written as Radium-223 and enzalutamide
- Radium-223 in Biochemically Recurrent Prostate CancerActive, not recruitingPhase 2National Cancer Institute (NCI)NCT04206319Written as Radium-223
- A Phase III Study of Radium-223 Dichloride in Patients With Symptomatic Hormone Refractory Prostate Cancer With Skeletal MetastasesCompletedPhase 3BayerNCT00699751Written as Radium-223 dichloride (Xofigo, BAY88-8223)
- Efficacy of Ra-223 in PSMA PET Optimally Selected PatientsActive, not recruitingPhase 2University of California, San FranciscoNCT05924672Written as Radium-223
- RAdium-223 and SABR Versus SABR for Oligometastatic Prostate CancersCompletedPhase 2Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsNCT04037358Written as Radium-223
- Phase III Radium 223 mCRPC-PEACE IIIActive, not recruitingPhase 3European Organisation for Research and Treatment of Cancer - EORTCNCT02194842Written as Ra223
- A Study to Assess How Radium-223 Distributes in the Body of Patients With Prostate Cancer Which Spread to the BonesCompletedPhase 1BayerNCT04521361Written as Radium-223 dichloride (Xofigo, BAY88-8223)
- Radium-223 and Radiotherapy in Hormone-Naïve Men With Oligometastatic Prostate Cancer to BoneCompletedPhase 2University of UtahNCT03304418Written as Radium Ra 223 Dichloride
- Radium-223 Dichloride and Abiraterone Acetate Compared to Placebo and Abiraterone Acetate for Men With Cancer of the Prostate When Medical or Surgical Castration Does Not Work and When the Cancer Has Spread to the Bone, Has Not Been Treated With Chemotherapy and is Causing no or Only Mild SymptomsCompletedPhase 3BayerNCT02043678Written as Radium-223 dichloride (Xofigo, BAY88-8223)
- Combination of Radium-223 and Lutetium-177 PSMA-I&T in Men with Metastatic Castration-Resistant Prostate CancerActive, not recruitingPhase 1/2Peter MacCallum Cancer Centre, AustraliaNCT05383079Written as Radium-223
- Trial of Rad-223 Activity in Asymptomatic Patients With mCRPC While on Abiraterone or Enzalutamide Besides AR-V7 StatusCompletedPhase 2MedSIRNCT03002220Written as radium-223
- Study to Test the Safety and How Radium-223 Dichloride an Alpha Particle-emitting Radioactive Agent Works in Combination With Pembrolizumab an Immune Checkpoint Inhibitor in Patients With Stage IV Non-small Cell Lung Cancer With Bone MetastasesTerminatedPhase 1BayerNCT03996473Written as Radium-223 dichloride (Xofigo, BAY 88-8223)
- Sequencing of Radium-223 and Docetaxel in Symptomatic Bone-only Metastatic Castration-resistant Prostate CancerActive, not recruitingPhase 2Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCSNCT03230734Written as Radium-223
- Prostate Cancer Intensive, Non-Cross Reactive Therapy (PRINT) for Castration Resistant Prostate Cancer (CRPC)CompletedPhase 2Icahn School of Medicine at Mount SinaiNCT02903160Written as Radium-223 dichloride
- Radium-223 Combined With Dexamethasone as First-line Therapy in Patients With M+CRPCActive, not recruitingPhase 4University Health Network, TorontoNCT03432949Written as Dexamethasone plus Radium-223
- Study of Radium-223 Dichloride in Combination With Exemestane and Everolimus Versus Placebo in Combination With Exemestane and Everolimus in Subjects With Bone Predominant HER2 Negative Hormone Receptor Positive Metastatic Breast CancerCompletedPhase 2BayerNCT02258451Written as Radium-223 dichloride (Xofigo, BAY88-8223)
See all 52 studies that test Radium →
Given in every arm · 5 — Radium is usual care beside what is tested
- A Study of Stereotactic Body Radiation Therapy and Radium (Ra-223) Dichloride in Prostate Cancer That Has Spread to the BonesCompletedPhase 2Memorial Sloan Kettering Cancer CenterNCT05133440Written as Radium dichloride
- Study Evaluating the Addition of Pembrolizumab to Radium-223 in mCRPCCompletedPhase 2Dana-Farber Cancer InstituteNCT03093428Written as Radium-223
- Exploratory Study of Radium-223 and VEGF-Targeted Therapy in Patients With Metastatic Renal Cell Carcinoma and Bone MetsCompletedPhase 1Dana-Farber Cancer InstituteNCT02406521Written as Radium-223
- A Randomized Phase IIa Efficacy and Safety Study of Radium-223 Dichloride With Abiraterone Acetate or Enzalutamide in Metastatic Castration-resistant Prostate Cancer (CRPC)CompletedPhase 2BayerNCT02034552Written as Radium-223 dichloride (Xofigo, BAY88-8223)
- A Study of Alpharadin With Docetaxel in Patients With Bone Metastasis From Castration-Resistant Prostate Cancer (CRPC)CompletedPhase 1/2BayerNCT01106352Written as Radium-223 dichloride (Xofigo, BAY88-8223)
As the comparator · 3 — what is tested is compared with Radium
- AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)RecruitingPhase 3AstraZenecaNCT07611110Written as Radium-223
- ProBio: A Biomarker Driven Study in Patients With Metastatic Prostate CancerRecruitingPhase 3Karolinska InstitutetNCT03903835Written as Radium Chloride Ra-223
- Rhenium-188-HEDP vs. Radium-223-chloride in Patients With Advanced Prostate Cancer Refractory to Hormonal TherapyStatus unknownPhase 3Amsterdam UMC, location VUmcNCT03458559Written as Radium-223 chloride
Codes
What other systems call Radium · ClinicalTrials.gg INT008150
- MeSH (NLM) D011883RadiumConfirmed NLM, Wikidata
- UNII (FDA) W90AYD6R3QRADIUMConfirmed FDA, NLM, Wikidata
- RxNorm 1546450Confirmed FDA, Wikidata
- Wikidata Q1128radiumConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C2391RadiumOne source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D011883 | Radium | Confirmed NLM, Wikidata |
| UNII (FDA) | W90AYD6R3Q | RADIUM | Confirmed FDA, NLM, Wikidata |
| RxNorm | 1546450 | — | Confirmed FDA, Wikidata |
| Wikidata | Q1128 | radium | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C2391 | Radium | One source FDA |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.